HitPredict

Interactor 1: PRP1 (Q12381)
Pre-mRNA-splicing factor prp1
Gene: PRP1

Interactor 2: BRR2 (Q9UT24)
Pre-mRNA-splicing factor brr2 (EC 3.6.4.13) (Pre-mRNA-splicing factor spp41) (Pre-mRNA-splicing helicase BRR2)
Gene: BRR2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	16133344, 15755920
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DEAD~TPR_8
Common GO terms	GO:0005634 - nucleus GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 906 Sp			1 2176
+	Hs
		271991 PRP6_HUMAN (5-717): 1.7e-41: 166: 16.15		U520_HUMAN (21-2167): 0: 1780: 48.24
+	Sp
		953585 CLF1_SCHPO (453-904): 1.48e-49: 188: 17.28		BRR2_SCHPO (1-2176): 0: 1739: 100.00
+	At
		98519 F4JZX8_ARATH (453-904): 5.02e-53: 199: 17.90		DEXHC_ARATH (17-2165): 0: 1702: 46.03
+	Sp
		1350845 SYF1_SCHPO (243-700): 4.43e-19: 94.5: 13.55		BRR2_SCHPO (1-2176): 0: 1739: 100.00
+	Dm
		54175 SYF1_DROME (423-905): 1.12e-27: 122: 11.61		U520_DROME (21-2166): 0: 1705: 47.80
+	At
		1338521 Q9LKU3_ARATH (341-902): 4.42e-20: 98: 12.01		DEXHC_ARATH (17-2165): 0: 1702: 46.03
+	Sc
		586385 PRP6_YEAST (6-904): 3.92e-107: 353: 25.35		BRR2_YEAST (19-2165): 0: 1349: 41.32
+	Sc
		697276 CLF1_YEAST (298-870): 3.23e-38: 154: 15.19		BRR2_YEAST (19-2165): 0: 1349: 41.32
+	Sp
		143158 PRP1_SCHPO (1-906): 0: 554: 100.00		YE02_SCHPO (388-1013): 1.8e-93: 330: 19.97
+	Hs
		175083 OGT1_HUMAN (109-539): 1.16e-49: 192: 12.81		DDX17_HUMAN (1279-1772): 9.55e-100: 341: 11.49
+	Hs
		133770 OGT1_HUMAN (109-539): 1.16e-49: 192: 12.81		DDX3X_HUMAN (1297-1770): 2.99e-98: 334: 12.92
+	Hs
		174608 OGT1_HUMAN (109-539): 1.16e-49: 192: 12.81		DDX5_HUMAN (1278-1767): 3.54e-97: 329: 11.38
+	Sp
		143121 CLF1_SCHPO (453-904): 1.48e-49: 188: 17.28		YE02_SCHPO (388-1013): 1.8e-93: 330: 19.97
+	Hs
		300219 PRP6_HUMAN (5-717): 1.7e-41: 166: 16.15		DDX17_HUMAN (1279-1772): 9.55e-100: 341: 11.49
+	Hs
		1074469 SKI3_HUMAN (471-903): 1.99e-22: 106: 11.07		SKI2_HUMAN (388-941): 6.8e-98: 348: 21.31
+	Hs
		300254 PRP6_HUMAN (5-717): 1.7e-41: 166: 16.15		DDX23_HUMAN (1271-1785): 6.11e-77: 276: 12.75
+	Sp
		143198 SYF1_SCHPO (243-700): 4.43e-19: 94.5: 13.55		YE02_SCHPO (388-1013): 1.8e-93: 330: 19.97
+	Sc
		810915 RRP5_YEAST (267-489): 2.01e-10: 67.1: 15.10		MTR4_YEAST (431-1027): 2.92e-99: 349: 18.15
+	Hs
		1058019 RRP5_HUMAN (549-903): 2.7e-24: 112: 13.95		DDX23_HUMAN (1271-1785): 6.11e-77: 276: 12.75
+	Hs
		1160966 CTR9_HUMAN (25-518): 4.93e-14: 78.8: 11.09		DDX23_HUMAN (1271-1785): 6.11e-77: 276: 12.75