HitPredict

Interactor 1: H32 (P84228)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (H3-clustered histone 2) (H3-clustered histone 3) (H3-clustered histone 4) (H3-clustered histone 6) (H3-clustered histone 7)
Gene: H3c2

Interactor 2: RBBP4 (Q60972)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20211137
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	CAF1C_H4-bd~Histone, Histone~WD40
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Mm			1 425
+	Hs
		998249 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		RBBP4_HUMAN (1-425): 2.89e-121: 360: 100.00
+	Mm
		999026 H31_MOUSE (1-136): 3.1e-62: 188: 99.27		RBBP4_MOUSE (1-425): 2.89e-121: 360: 100.00
+	Hs
		1016804 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		RBBP4_HUMAN (1-425): 2.89e-121: 360: 100.00
+	Mm
		1017353 H33_MOUSE (1-136): 2.57e-61: 186: 97.06		RBBP4_MOUSE (1-425): 2.89e-121: 360: 100.00
+	Hs
		1066324 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		RBBP4_HUMAN (1-425): 2.89e-121: 360: 100.00
+	Hs
		998350 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		TAF5_HUMAN (2-226): 1.24e-38: 150: 15.22
+	Hs
		284955 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		TAF5L_HUMAN (2-246): 1.35e-39: 151: 13.78
+	Hs
		1016886 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		TAF5_HUMAN (2-226): 1.24e-38: 150: 15.22
+	Hs
		1149773 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		TAF5_HUMAN (2-226): 1.24e-38: 150: 15.22
+	Hs
		998364 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		RBBP7_HUMAN (9-210): 1.64e-35: 137: 12.56
+	Mm
		999023 H31_MOUSE (1-136): 3.1e-62: 188: 99.27		Q3UJI2_MOUSE (9-210): 3.75e-35: 136: 12.11
+	Hs
		1016894 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		RBBP7_HUMAN (9-210): 1.64e-35: 137: 12.56
+	Hs
		1158856 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		RBBP7_HUMAN (9-210): 1.64e-35: 137: 12.56
+	Hs
		964837 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		WDR5_HUMAN (267-425): 2.01e-35: 135: 25.61
+	Mm
		1017349 H33_MOUSE (1-136): 2.57e-61: 186: 97.06		Q3UJI2_MOUSE (9-210): 3.75e-35: 136: 12.11
+	Mm
		1016754 H32_MOUSE (1-136): 6.24e-61: 185: 100.00		Q3UJI2_MOUSE (9-210): 3.75e-35: 136: 12.11
+	Hs
		964848 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		WDR5_HUMAN (267-425): 2.01e-35: 135: 25.61
+	Hs
		964981 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		WDR5_HUMAN (267-425): 2.01e-35: 135: 25.61
+	Hs
		998741 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		GRWD1_HUMAN (263-425): 9.87e-26: 110: 23.56
+	Hs
		998532 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		DAW1_HUMAN (9-106): 5.39e-21: 96: 8.74