Protein: TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L) (PCAF-associated factor 65 beta) (PAF65-beta)

Gene: TAF5L
Organism: Homo sapiens
Interactions: 104
UniProt ID: O75529

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0006282 - regulation of DNA repair
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

284973

TADA1
Transcriptional adapter 1

5

1

High-throughput

0.919

High

284971

KAT2A
Histone acetyltransferase KAT2A

5

20

Small-scale

0.912

High

284972

KAT2B
Histone acetyltransferase KAT2B

5

20

Small-scale

0.912

High

284985

TAF9B
Transcription initiation factor TFIID subunit 9B

4

10

High-throughput

0.895

High

284944

TAF10
Transcription initiation factor TFIID subunit 10

4

5

Small-scale

0.873

High

284994

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

3

10

High-throughput

0.861

High

284999

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

3

7

High-throughput

0.861

High

284969

SP20H
Transcription factor SPT20 homolog

4

0

High-throughput

0.836

High

284996

TRRAP
Transformation/transcription domain-associated protein

2

11

High-throughput

0.789

High

284954

TAF9
Transcription initiation factor TFIID subunit 9

2

10

Small-scale

0.754

High

284948

AT7L3
Ataxin-7-like protein 3

8

1

Small-scale

0.748

High

284974

SGF29
SAGA-associated factor 29

7

3

High-throughput

0.747

High

284773

TADA3
Transcriptional adapter 3

5

7

High-throughput

0.714

High

284965

TAD2B
Transcriptional adapter 2-beta

5

14

High-throughput

0.714

High

283585

SUPT3
Transcription initiation protein SPT3 homolog

5

6

Small-scale

0.709

High

284949

SF3B3
Splicing factor 3B subunit 3

1

14

High-throughput

0.691

High

284953

TAF12
Transcription initiation factor TFIID subunit 12

4

6

High-throughput

0.691

High

284962

FOXR2
Forkhead box protein R2

3

8

High-throughput

0.667

High

284991

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

2

High-throughput

0.665

High

284923

H2AX
Histone H2AX

1

9

High-throughput

0.656

High

284911

MYC
Myc proto-oncogene protein

3

20

High-throughput

0.640

High

284921

MYCL
Protein L-Myc

2

17

High-throughput

0.628

High

284939

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.618

High

67118

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

1

10

High-throughput

0.618

High

284937

H4
Histone H4

1

7

High-throughput

0.618

High

284938

H2B1C
Histone H2B type 1-C/E/F/G/I

1

7

High-throughput

0.618

High

284952

EZH2
Histone-lysine N-methyltransferase EZH2

1

15

Small-scale

0.618

High

284963

UBP51
Ubiquitin carboxyl-terminal hydrolase 51

1

15

High-throughput

0.618

High

284983

CSR2B
Cysteine-rich protein 2-binding protein

1

7

High-throughput

0.618

High

284995

WDR37
WD repeat-containing protein 37

1

20

High-throughput

0.618

High

184669

ATX7
Ataxin-7

2

9

Small-scale

0.611

High

284986

ENY2
Transcription and mRNA export factor ENY2

2

1

High-throughput

0.611

High

284957

TBB8
Tubulin beta-8 chain

3

19

High-throughput

0.609

High

186155

LX15B
Polyunsaturated fatty acid lipoxygenase ALOX15B

2

0

High-throughput

0.602

High

284908

ST65G
STAGA complex 65 subunit gamma

1

0

High-throughput

0.586

High

284924

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.578

High

284917

PAI2
Plasminogen activator inhibitor 2

2

5

High-throughput

0.574

High

284968

PCD20
Protocadherin-20

2

1

High-throughput

0.574

High

284914

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

219673

FOXO3
Forkhead box protein O3

1

13

High-throughput

0.554

High

284982

PKHA4
Pleckstrin homology domain-containing family A member 4

1

15

High-throughput

0.553

High

284951

CEBPE
CCAAT/enhancer-binding protein epsilon

1

8

High-throughput

0.541

High

284926

TBP
TATA-box-binding protein

1

8

High-throughput

0.536

High

284930

KI67
Proliferation marker protein Ki-67

1

8

High-throughput

0.536

High

284934

IMA5
Importin subunit alpha-5

1

6

High-throughput

0.536

High

284940

NOTC2
Neurogenic locus notch homolog protein 2

1

8

High-throughput

0.536

High

284946

TBB3
Tubulin beta-3 chain

1

19

High-throughput

0.536

High

284980

SF3B5
Splicing factor 3B subunit 5

1

2

High-throughput

0.536

High

284955

H31T
Histone H3.1t

1

11

High-throughput

0.527

High

284979

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.514

High

284931

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.513

High

284975

CSRN1
Cysteine/serine-rich nuclear protein 1

1

0

High-throughput

0.513

High

284925

ANXA7
Annexin A7

1

2

High-throughput

0.508

High

284927

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

High-throughput

0.508

High

284950

T22D1
TSC22 domain family protein 1

1

18

High-throughput

0.508

High

817

A0A096LNW4
PRAME family member 9

1

1

High-throughput

0.489

High

270866

CLAP2
CLIP-associating protein 2

1

4

High-throughput

0.489

High

284920

CCL3
C-C motif chemokine 3

1

2

High-throughput

0.489

High

284956

HFE
Hereditary hemochromatosis protein

1

2

High-throughput

0.489

High

284981

CAD23
Cadherin-23

1

1

High-throughput

0.489

High

284993

TFR2
Transferrin receptor protein 2

1

1

High-throughput

0.489

High

284997

PCDB3
Protocadherin beta-3

1

1

High-throughput

0.489

High

284998

PCDGH
Protocadherin gamma-B5

1

1

High-throughput

0.489

High

142758

NFIB
Nuclear factor 1 B-type

1

14

High-throughput

0.479

High

283405

TAD2A
Transcriptional adapter 2-alpha

1

20

High-throughput

0.479

High

284909

KLF8
Krueppel-like factor 8

1

17

High-throughput

0.479

High

284910

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

11

High-throughput

0.479

High

284915

P53
Cellular tumor antigen p53

1

4

Small-scale

0.479

High

284918

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

284922

MYOD1
Myoblast determination protein 1

1

2

High-throughput

0.479

High

284928

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

284929

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

284932

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.479

High

284933

MECP2
Methyl-CpG-binding protein 2

1

7

High-throughput

0.479

High

284935

KLF3
Krueppel-like factor 3

1

17

High-throughput

0.479

High

284936

MAX
Protein max

1

20

Small-scale

0.479

High

284941

SOX4
Transcription factor SOX-4

1

20

High-throughput

0.479

High

284942

NFIA
Nuclear factor 1 A-type

1

19

High-throughput

0.479

High

284943

TP53B
TP53-binding protein 1

1

5

High-throughput

0.479

High

284947

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

284960

EDC4
Enhancer of mRNA-decapping protein 4

1

9

High-throughput

0.479

High

284964

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

284966

JAZF1
Juxtaposed with another zinc finger protein 1

1

2

High-throughput

0.479

High

284967

ZZZ3
ZZ-type zinc finger-containing protein 3

1

2

High-throughput

0.479

High

284970

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

284977

ELF4
ETS-related transcription factor Elf-4

1

18

High-throughput

0.479

High

284978

KLF6
Krueppel-like factor 6

1

16

High-throughput

0.479

High

284987

MBIP1
MAP3K12-binding inhibitory protein 1

1

3

High-throughput

0.479

High

284988

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

284990

ZMYM2
Zinc finger MYM-type protein 2

1

4

High-throughput

0.479

High

284992

YETS2
YEATS domain-containing protein 2

1

20

High-throughput

0.479

High

284961

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

230227

CREB3
Cyclic AMP-responsive element-binding protein 3

1

6

High-throughput

0.445

High

284976

CDC5L
Cell division cycle 5-like protein

1

6

High-throughput

0.445

High

284959

AT7L2
Ataxin-7-like protein 2

1

2

High-throughput

0.437

High

284989

HECW2
E3 ubiquitin-protein ligase HECW2

1

2

High-throughput

0.437

High

284913

FRIL
Ferritin light chain

1

3

High-throughput

0.407

High

284919

RAP2A
Ras-related protein Rap-2a

1

4

High-throughput

0.407

High

284984

PLAC1
Placenta-specific protein 1

3

0

High-throughput

0.347

High

284916

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

0

High-throughput

0.279

Low

284945

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

284958

H1BP3
HCLS1-binding protein 3

1

0

High-throughput

0.279

Low

284912

TTHY
Transthyretin

1

0

High-throughput

0.265

Low

190695

MPPD1
Metallophosphoesterase domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025