HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35271311, 36089195
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006997 - nucleus organization GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 2115
+	Hs
		998327 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		NUMA1_HUMAN (1-2115): 3.94e-159: 544: 100.00
+	Hs
		1134622 H32_HUMAN (1-136): 5.34e-59: 180: 97.06		NUMA1_HUMAN (1-2115): 3.94e-159: 544: 100.00
+	Hs
		176962 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		CE290_HUMAN (257-2069): 1.44e-48: 194: 12.21
+	Hs
		176989 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		CE290_HUMAN (257-2069): 1.44e-48: 194: 12.21
+	Hs
		772736 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		MYH9_HUMAN (1033-1891): 1.2e-33: 145: 10.62
+	Hs
		773155 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		MYH10_HUMAN (1257-2089): 8.04e-33: 142: 11.87
+	Hs
		773213 H32_HUMAN (1-136): 5.34e-59: 180: 97.06		MYH10_HUMAN (1257-2089): 8.04e-33: 142: 11.87
+	Hs
		1143133 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		PLEC_HUMAN (628-2114): 9.11e-27: 122: 10.00
+	Hs
		998966 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		MYH15_HUMAN (973-1671): 5.7e-09: 63.9: 20.39