HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	29568061, 34079125, 36089195, 34349018, 35271311
Identification Methods	proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 2115
+	Hs
		1016868 H33_HUMAN (1-136): 1.45e-61: 186: 96.32		NUMA1_HUMAN (1-2115): 3.94e-159: 544: 100.00
+	Hs
		1134622 H32_HUMAN (1-136): 3.8e-61: 186: 99.27		NUMA1_HUMAN (1-2115): 3.94e-159: 544: 100.00
+	Hs
		176962 H31_HUMAN (1-136): 1.85e-62: 189: 100.00		CE290_HUMAN (257-2069): 1.44e-48: 194: 12.21
+	Hs
		176989 H31T_HUMAN (1-136): 9.24e-62: 187: 97.06		CE290_HUMAN (257-2069): 1.44e-48: 194: 12.21
+	Hs
		772736 H31_HUMAN (1-136): 1.85e-62: 189: 100.00		MYH9_HUMAN (1033-1891): 1.2e-33: 145: 10.62
+	Hs
		773155 H31_HUMAN (1-136): 1.85e-62: 189: 100.00		MYH10_HUMAN (1257-2089): 8.04e-33: 142: 11.87
+	Hs
		773213 H32_HUMAN (1-136): 3.8e-61: 186: 99.27		MYH10_HUMAN (1257-2089): 8.04e-33: 142: 11.87
+	Hs
		1143133 H31T_HUMAN (1-136): 9.24e-62: 187: 97.06		PLEC_HUMAN (628-2114): 9.11e-27: 122: 10.00
+	Hs
		998966 H31_HUMAN (1-136): 1.85e-62: 189: 100.00		MYH15_HUMAN (973-1671): 5.7e-09: 63.9: 20.39