Protein: CE290
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)

Gene: CE290, CEP290
Organism: Homo sapiens
Interactions: 182
UniProt ID: O15078

Gene Ontology (top 5):
GO:0001822 - kidney development
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

176980

IQCB1
IQ calmodulin-binding motif-containing protein 1

10

9

Small-scale

0.758

High

176908

CP110
Centriolar coiled-coil protein of 110 kDa

7

2

Small-scale

0.742

High

177025

CEP76
Centrosomal protein of 76 kDa

6

1

Small-scale

0.722

High

177016

CEP97
Centrosomal protein of 97 kDa

5

4

Small-scale

0.703

High

176943

MCM7
DNA replication licensing factor MCM7

3

18

High-throughput

0.667

High

177010

PEG10
Retrotransposon-derived protein PEG10

3

1

High-throughput

0.667

High

177038

DTBP1
Dysbindin

3

1

High-throughput

0.667

High

176983

PCM1
Pericentriolar material 1 protein

4

5

Small-scale

0.666

High

177040

NEUL4
Neuralized-like protein 4

4

6

Small-scale

0.666

High

177077

CP131
Centrosomal protein of 131 kDa

3

20

Small-scale

0.650

High

176997

CE162
Centrosomal protein of 162 kDa

3

20

Small-scale

0.650

High

177055

BBLN
Bublin coiled-coil protein

3

0

High-throughput

0.646

High

177063

MED4
Mediator of RNA polymerase II transcription subunit 4

3

2

High-throughput

0.643

High

176918

CEP43
Centrosomal protein 43

2

1

High-throughput

0.635

High

177050

LZTS2
Leucine zipper putative tumor suppressor 2

2

20

High-throughput

0.628

High

177074

PNMA2
Paraneoplastic antigen Ma2

4

10

High-throughput

0.619

High

176915

OFD1
Centriole and centriolar satellite protein OFD1

2

2

High-throughput

0.612

High

176995

CE170
Centrosomal protein of 170 kDa

2

20

High-throughput

0.612

High

177001

CP135
Centrosomal protein of 135 kDa

2

20

High-throughput

0.611

High

177023

NEDD1
Protein NEDD1

2

18

High-throughput

0.611

High

177065

PICK1
PRKCA-binding protein

2

1

High-throughput

0.606

High

176972

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

2

3

High-throughput

0.588

High

177014

MIB1
E3 ubiquitin-protein ligase MIB1

2

12

High-throughput

0.588

High

177028

PIBF1
Progesterone-induced-blocking factor 1

2

1

High-throughput

0.588

High

177069

CEP72
Centrosomal protein of 72 kDa

2

12

High-throughput

0.588

High

177078

ADIP
Afadin- and alpha-actinin-binding protein

2

1

High-throughput

0.588

High

176994

CCD14
Coiled-coil domain-containing protein 14

2

0

High-throughput

0.585

High

176992

ZN423
Zinc finger protein 423

1

4

Small-scale

0.573

High

130307

SPT5H
Transcription elongation factor SPT5

2

9

High-throughput

0.571

High

176912

USO1
General vesicular transport factor p115

2

20

High-throughput

0.571

High

176917

PCNT
Pericentrin

2

19

High-throughput

0.571

High

176919

HERC2
E3 ubiquitin-protein ligase HERC2

2

17

High-throughput

0.571

High

176921

LDHA
L-lactate dehydrogenase A chain

2

10

High-throughput

0.571

High

176938

UBA1
Ubiquitin-like modifier-activating enzyme 1

2

1

High-throughput

0.571

High

176948

KC1E
Casein kinase I isoform epsilon

2

7

High-throughput

0.571

High

176950

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

2

1

High-throughput

0.571

High

176964

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

2

7

High-throughput

0.571

High

176965

AKA12
A-kinase anchor protein 12

2

17

High-throughput

0.571

High

176967

SSBP
Single-stranded DNA-binding protein, mitochondrial

2

3

High-throughput

0.571

High

176974

TADBP
TAR DNA-binding protein 43

2

14

High-throughput

0.571

High

176987

MARE1
Microtubule-associated protein RP/EB family member 1

2

13

High-throughput

0.571

High

176993

KIF7
Kinesin-like protein KIF7

2

8

High-throughput

0.571

High

177012

CAND1
Cullin-associated NEDD8-dissociated protein 1

2

8

High-throughput

0.571

High

177031

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

2

1

High-throughput

0.571

High

177049

CCD77
Coiled-coil domain-containing protein 77

2

0

High-throughput

0.547

High

176952

MK10
Mitogen-activated protein kinase 10

1

12

High-throughput

0.541

High

176953

TTC3
E3 ubiquitin-protein ligase TTC3

1

9

High-throughput

0.541

High

176923

FRIL
Ferritin light chain

1

2

High-throughput

0.536

High

176939

CRCM
Colorectal mutant cancer protein

1

18

High-throughput

0.536

High

176970

LG3BP
Galectin-3-binding protein

1

14

High-throughput

0.536

High

176998

FAXC
Failed axon connections homolog

1

3

High-throughput

0.536

High

177034

TRI52
E3 ubiquitin-protein ligase TRIM52

1

20

High-throughput

0.536

High

177073

KLHL3
Kelch-like protein 3

1

5

High-throughput

0.536

High

177075

NP1L2
Nucleosome assembly protein 1-like 2

1

5

High-throughput

0.536

High

177070

C2D2A
Coiled-coil and C2 domain-containing protein 2A

1

1

Small-scale

0.527

High

177027

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

2

9

High-throughput

0.521

High

176957

H2BFS
Histone H2B type F-S

1

20

High-throughput

0.515

High

176989

H31T
Histone H3.1t

1

16

High-throughput

0.515

High

177033

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.515

High

177048

H2A1J
Histone H2A type 1-J

1

15

High-throughput

0.515

High

177081

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

0

High-throughput

0.513

High

177017

CCD13
Coiled-coil domain-containing protein 13

1

20

Small-scale

0.484

High

177029

CBP
CREB-binding protein

1

13

Small-scale

0.481

High

163858

NDC80
Kinetochore protein NDC80 homolog

1

18

High-throughput

0.479

High

176906

CE290
Centrosomal protein of 290 kDa

1

19

Small-scale

0.479

High

176907

ARPC3
Actin-related protein 2/3 complex subunit 3

1

3

High-throughput

0.479

High

176909

CF410
Cilia- and flagella-associated protein 410

1

17

High-throughput

0.479

High

176913

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

18

High-throughput

0.479

High

176920

LATS1
Serine/threonine-protein kinase LATS1

1

20

High-throughput

0.479

High

176922

NB5R3
NADH-cytochrome b5 reductase 3

1

1

High-throughput

0.479

High

176924

ESR1
Estrogen receptor

1

20

Small-scale

0.479

High

176926

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

6

High-throughput

0.479

High

176927

HMGN1
Non-histone chromosomal protein HMG-14

1

2

High-throughput

0.479

High

176928

K1C18
Keratin, type I cytoskeletal 18

1

20

High-throughput

0.479

High

176929

HS90B
Heat shock protein HSP 90-beta

1

11

High-throughput

0.479

High

176930

K1C19
Keratin, type I cytoskeletal 19

1

18

High-throughput

0.479

High

176933

BIP
Endoplasmic reticulum chaperone BiP

1

20

High-throughput

0.479

High

176936

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

4

High-throughput

0.479

High

176937

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

1

High-throughput

0.479

High

176941

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

3

High-throughput

0.479

High

176946

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

9

High-throughput

0.479

High

176947

MDHC
Malate dehydrogenase, cytoplasmic

1

10

High-throughput

0.479

High

176949

BAP31
B-cell receptor-associated protein 31

1

11

High-throughput

0.479

High

176951

RM12
Large ribosomal subunit protein bL12m

1

1

High-throughput

0.479

High

176954

KAD2
Adenylate kinase 2, mitochondrial

1

2

High-throughput

0.479

High

176955

FOXA1
Hepatocyte nuclear factor 3-alpha

1

4

High-throughput

0.479

High

176958

MTPN
Myotrophin

1

20

High-throughput

0.479

High

176959

RAB8A
Ras-related protein Rab-8A

1

11

Small-scale

0.479

High

176960

RAB2A
Ras-related protein Rab-2A

1

13

High-throughput

0.479

High

176961

H4
Histone H4

1

13

High-throughput

0.479

High

176962

H31
Histone H3.1

1

16

High-throughput

0.479

High

176963

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

20

High-throughput

0.479

High

176966

DYST
Dystonin

1

19

High-throughput

0.479

High

176968

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

176971

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

20

High-throughput

0.479

High

176973

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

20

High-throughput

0.479

High

176975

MTA1
Metastasis-associated protein MTA1

1

10

High-throughput

0.479

High

176976

SQSTM
Sequestosome-1

1

18

High-throughput

0.479

High

176977

DSG2
Desmoglein-2

1

12

High-throughput

0.479

High

176978

DCTN1
Dynactin subunit 1

1

20

High-throughput

0.479

High

176979

SUZ12
Polycomb protein SUZ12

1

3

High-throughput

0.479

High

176981

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

176982

EEA1
Early endosome antigen 1

1

20

High-throughput

0.479

High

176985

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

8

High-throughput

0.479

High

176988

EZH2
Histone-lysine N-methyltransferase EZH2

1

18

High-throughput

0.479

High

176990

CSPP1
Centrosome and spindle pole-associated protein 1

1

1

High-throughput

0.479

High

176996

CCD18
Coiled-coil domain-containing protein 18

1

20

High-throughput

0.479

High

176999

CE350
Centrosome-associated protein 350

1

20

High-throughput

0.479

High

177000

RN123
E3 ubiquitin-protein ligase RNF123

1

20

High-throughput

0.479

High

177003

SAS6
Spindle assembly abnormal protein 6 homolog

1

19

High-throughput

0.479

High

177004

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

1

10

High-throughput

0.479

High

177006

CE128
Centrosomal protein of 128 kDa

1

20

High-throughput

0.479

High

177008

HAUS6
HAUS augmin-like complex subunit 6

1

1

High-throughput

0.479

High

177011

LUZP1
Leucine zipper protein 1

1

20

High-throughput

0.479

High

177013

CEP57
Centrosomal protein of 57 kDa

1

1

High-throughput

0.479

High

177015

LRC49
Leucine-rich repeat-containing protein 49

1

10

High-throughput

0.479

High

177019

NIN
Ninein

1

19

High-throughput

0.479

High

177021

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

177022

RN149
E3 ubiquitin-protein ligase RNF149

1

13

High-throughput

0.479

High

177024

THOC2
THO complex subunit 2

1

19

High-throughput

0.479

High

177026

CIP2A
Protein CIP2A

1

17

High-throughput

0.479

High

177030

RPGR
X-linked retinitis pigmentosa GTPase regulator

1

13

Small-scale

0.479

High

177032

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

19

Small-scale

0.479

High

177036

HAUS1
HAUS augmin-like complex subunit 1

1

1

High-throughput

0.479

High

177037

TBC31
TBC1 domain family member 31

1

20

High-throughput

0.479

High

177039

PAWR
PRKC apoptosis WT1 regulator protein

1

1

High-throughput

0.479

High

177043

NEK1
Serine/threonine-protein kinase Nek1

1

20

High-throughput

0.479

High

177051

GPTC1
G patch domain-containing protein 1

1

6

High-throughput

0.479

High

177054

TCHP
Trichoplein keratin filament-binding protein

1

20

High-throughput

0.479

High

177059

DDX47
Probable ATP-dependent RNA helicase DDX47

1

12

High-throughput

0.479

High

177060

CCDC8
Coiled-coil domain-containing protein 8

1

10

High-throughput

0.479

High

177064

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.479

High

177067

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

2

High-throughput

0.479

High

177068

HYPK
Huntingtin-interacting protein K

1

1

Small-scale

0.479

High

177071

E2AK4
eIF-2-alpha kinase GCN2

1

4

High-throughput

0.479

High

177072

WRP73
WD repeat-containing protein WRAP73

1

20

High-throughput

0.479

High

177076

CC14A
Dual specificity protein phosphatase CDC14A

1

13

High-throughput

0.479

High

177079

NINL
Ninein-like protein

1

20

High-throughput

0.479

High

177082

NDK7
Nucleoside diphosphate kinase homolog 7

1

4

High-throughput

0.479

High

176911

CE104
Centrosomal protein of 104 kDa

1

0

High-throughput

0.458

High

176934

GYS1
Glycogen [starch] synthase, muscle

1

0

High-throughput

0.458

High

176935

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

176940

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.458

High

176942

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.458

High

176945

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.458

High

176969

PLP2
Proteolipid protein 2

1

0

High-throughput

0.458

High

176984

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.458

High

176986

TESK1
Dual specificity testis-specific protein kinase 1

1

0

High-throughput

0.458

High

176991

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

177002

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.458

High

177005

TPGS1
Tubulin polyglutamylase complex subunit 1

1

0

High-throughput

0.458

High

177035

ISOC1
Isochorismatase domain-containing protein 1

1

0

High-throughput

0.458

High

177042

CEP20
Centrosomal protein 20

1

0

High-throughput

0.458

High

177046

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.458

High

177047

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.458

High

177053

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.458

High

177058

PIP30
PSME3-interacting protein

1

0

High-throughput

0.458

High

177061

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.458

High

177062

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

1

0

High-throughput

0.458

High

177083

CCD61
Centrosomal protein CCDC61

1

0

High-throughput

0.458

High

177045

CDC5L
Cell division cycle 5-like protein

1

9

High-throughput

0.457

High

177066

DISC1
Disrupted in schizophrenia 1 protein

1

9

High-throughput

0.457

High

176916

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

1

High-throughput

0.445

High

176931

CALM2
Calmodulin-2

1

4

High-throughput

0.445

High

176932

CALM3
Calmodulin-3

1

4

High-throughput

0.445

High

176944

BMI1
Polycomb complex protein BMI-1

1

20

High-throughput

0.445

High

176956

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

20

High-throughput

0.445

High

177007

TBA1A
Tubulin alpha-1A chain

1

10

High-throughput

0.445

High

177020

POC5
Centrosomal protein POC5

1

8

Small-scale

0.445

High

177044

CK5P2
CDK5 regulatory subunit-associated protein 2

1

20

High-throughput

0.445

High

104857

APRIO
Alternative prion protein

1

9

High-throughput

0.437

High

176914

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.437

High

176925

GBA1
Lysosomal acid glucosylceramidase

1

1

Small-scale

0.437

High

177052

WDR83
WD repeat domain-containing protein 83

1

20

High-throughput

0.437

High

176910

KATIP
Katanin-interacting protein

1

0

High-throughput

0.426

High

177018

BBS5
BBSome complex member BBS5

1

0

Small-scale

0.426

High

177056

TALD3
Protein TALPID3

1

0

Small-scale

0.426

High

177057

BBS2
BBSome complex member BBS2

1

0

Small-scale

0.426

High

177009

K1328
Protein hinderin

2

0

High-throughput

0.316

High

177041

CC138
Coiled-coil domain-containing protein 138

2

0

High-throughput

0.307

High

177080

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025