HitPredict

Interactor 1: CDC20 (Q12834)
Cell division cycle protein 20 homolog (p55CDC)
Gene: CDC20

Interactor 2: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	19826003, 22990118
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 499 Hs			1 2089
+	Hs
		1056932 SNR40_HUMAN (340-499): 1.5e-30: 123: 20.25		MDC1_HUMAN (1-2089): 0: 665: 100.00
+	Hs
		1057025 FZR1_HUMAN (315-495): 1.51e-24: 108: 19.02		MDC1_HUMAN (1-2089): 0: 665: 100.00
+	Hs
		801107 CDC20_HUMAN (1-499): 1.18e-136: 405: 100.00		KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53
+	Hs
		1017399 CDC20_HUMAN (1-499): 1.18e-136: 405: 100.00		PAXI1_HUMAN (1840-2081): 6.55e-55: 212: 27.56
+	Hs
		1346974 NLE1_HUMAN (64-471): 2.26e-89: 283: 18.93		NCOR2_HUMAN (149-1902): 1.48e-73: 276: 8.36
+	Hs
		801423 NLE1_HUMAN (64-471): 2.26e-89: 283: 18.93		KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53
+	Hs
		1173203 FBXW7_HUMAN (210-496): 2.2e-71: 242: 17.81		PAXI1_HUMAN (1840-2081): 6.55e-55: 212: 27.56
+	Hs
		1288413 SNR40_HUMAN (340-499): 1.5e-30: 123: 20.25		NCOR2_HUMAN (149-1902): 1.48e-73: 276: 8.36
+	Hs
		1346970 NLE1_HUMAN (64-471): 2.26e-89: 283: 18.93		SRRM2_HUMAN (133-1326): 2.15e-19: 98.4: 8.08
+	Hs
		801299 SNR40_HUMAN (340-499): 1.5e-30: 123: 20.25		KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53
+	Hs
		1281511 FBXW7_HUMAN (210-496): 2.2e-71: 242: 17.81		C170B_HUMAN (751-1981): 3.73e-25: 116: 8.69
+	Hs
		1302927 NLE1_HUMAN (64-471): 2.26e-89: 283: 18.93		MINT_HUMAN (159-1473): 1.72e-10: 68.9: 10.33
+	Hs
		1281391 FBXW7_HUMAN (210-496): 2.2e-71: 242: 17.81		PRR36_HUMAN (1354-1950): 2.23e-12: 74.9: 11.46
+	Hs
		1264784 SNR40_HUMAN (340-499): 1.5e-30: 123: 20.25		TITIN_HUMAN (175-1895): 2.81e-32: 141: 8.72
+	Hs
		1264822 FZR1_HUMAN (315-495): 1.51e-24: 108: 19.02		TITIN_HUMAN (175-1895): 2.81e-32: 141: 8.72
+	Hs
		793042 LIS1_HUMAN (337-498): 1.74e-37: 143: 16.56		SRRM2_HUMAN (133-1326): 2.15e-19: 98.4: 8.08
+	Hs
		1288394 SNR40_HUMAN (340-499): 1.5e-30: 123: 20.25		SRRM2_HUMAN (133-1326): 2.15e-19: 98.4: 8.08
+	Hs
		1288258 SNR40_HUMAN (340-499): 1.5e-30: 123: 20.25		MINT_HUMAN (159-1473): 1.72e-10: 68.9: 10.33
+	Hs
		1332354 FZR1_HUMAN (315-495): 1.51e-24: 108: 19.02		PRR36_HUMAN (1354-1950): 2.23e-12: 74.9: 11.46
+	Hs
		965173 FZR1_HUMAN (315-495): 1.51e-24: 108: 19.02		ANK2_HUMAN (608-1849): 1.3e-11: 72.7: 10.40