HitPredict

Interactor 1: MERTK (Q12866)
Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)
Gene: MERTK

Interactor 2: GAS6 (Q14393)
Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand)
Gene: GAS6

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 8939948, 9160883
Identification Methods pull down, surface plasmon resonance
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_CA~fn3, Ig_3~Laminin_G_1
Common GO terms GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0006468 - protein phosphorylation
GO:0006909 - phagocytosis
GO:0007166 - cell surface receptor signaling pathway
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 999
Hs

1 678
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024