Interactor 1: MED20 (P91641)
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (Protein trf-proximal) (dMED20) (dTrap26) (dTrfp)
Gene: MED20

Interactor 2: MED18 (Q9XZT1)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (dp28b)
Gene: MED18

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 14605208, 37061542, 22036573, unassigned2874, 38944040
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med18~Med20
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 252
Dm

1 217
+ Hs

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Last updated: 11Aug2025