HitPredict

Interactor 1: FOXL1 (Q12952)
Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7)
Gene: FOXL1

Interactor 2: KMT2C (Q8NEZ4)
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)
Gene: KMT2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 4911
+	Hs
		877807 FOXA1_HUMAN (5-320): 1.41e-80: 255: 30.27		KMT2C_HUMAN (1-4911): 0: 2416: 100.00
+	Hs
		1021235 FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02		KMT2C_HUMAN (1-4911): 0: 2416: 100.00
+	Hs
		877733 FOXA1_HUMAN (5-320): 1.41e-80: 255: 30.27		CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56
+	Hs
		877716 FOXA1_HUMAN (5-320): 1.41e-80: 255: 30.27		CHD3_HUMAN (390-526): 1.86e-31: 139: 21.38
+	Hs
		152638 FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82
+	Hs
		1021109 FOXC1_HUMAN (9-280): 1.15e-53: 186: 35.86		CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56
+	Hs
		877612 FOXG1_HUMAN (48-224): 2.13e-52: 182: 40.68		CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56
+	Hs
		964181 FOXK2_HUMAN (1-245): 2.81e-51: 182: 32.45		CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56
+	Hs
		126461 FOXE1_HUMAN (6-312): 1.36e-52: 179: 33.86		CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56
+	Hs
		964284 FOXK2_HUMAN (1-245): 2.81e-51: 182: 32.45		SET1B_HUMAN (4778-4911): 3.56e-24: 115: 51.11
+	Hs
		1021240 FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02		DPF1_HUMAN (350-435): 3.04e-13: 77: 40.45
+	Hs
		964282 FOXK2_HUMAN (1-245): 2.81e-51: 182: 32.45		KMT2B_HUMAN (1985-2617): 4.3e-09: 65.8: 12.11
+	Hs
		152626 FOXK2_HUMAN (1-245): 2.81e-51: 182: 32.45		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82
+	Hs
		1021241 FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02		REQU_HUMAN (359-435): 2.72e-12: 74.3: 41.25
+	Hs
		952846 FOXK1_HUMAN (7-281): 1.72e-46: 169: 29.83		REQU_HUMAN (359-435): 2.72e-12: 74.3: 41.25
+	Hs
		152637 FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82