HitPredict

Interactor 1: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Interactor 2: MPP2 (Q14168)
MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2)
Gene: MPP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Guanylate_kin~Guanylate_kin, Guanylate_kin~PDZ, Guanylate_kin~SH3_2, L27~L27_1, PDZ~PDZ, PDZ~SH3_2, Guanylate_kin~SH3_1, SH3_1~SH3_2
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005911 - cell-cell junction
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 904 Hs			1 576
+	Hs
		159200 DLG1_HUMAN (1-904): 0: 725: 100.00		CSKP_HUMAN (7-576): 4.46e-145: 443: 36.50
+	Mm
		251104 DLG1_MOUSE (1-904): 0: 720: 95.47		CSKP_MOUSE (7-576): 6.08e-145: 443: 36.50
+	Rn
		1144009 DLG1_RAT (1-904): 0: 701: 92.54		CSKP_RAT (7-576): 1.25e-141: 434: 36.23
+	Rn
		292499 DLG1_RAT (1-904): 0: 701: 92.54		MPP3_RAT (1-575): 3.03e-130: 395: 30.62
+	Hs
		91344 DLG1_HUMAN (1-904): 0: 725: 100.00		E5RI47_HUMAN (12-230): 1.18e-119: 353: 85.39
+	Hs
		159249 DLG3_HUMAN (139-904): 0: 585: 66.28		CSKP_HUMAN (7-576): 4.46e-145: 443: 36.50
+	Hs
		1021482 DLG1_HUMAN (1-904): 0: 725: 100.00		DLG1_HUMAN (1-248): 7.96e-18: 89.6: 13.88
+	Hs
		1021501 DLG1_HUMAN (1-904): 0: 725: 100.00		DLG2_HUMAN (153-253): 1.08e-14: 79.6: 18.58
+	Mm
		1143387 DLG1_MOUSE (1-904): 0: 720: 95.47		DLG4_MOUSE (111-248): 3.45e-16: 84.2: 18.62
+	Hs
		1021542 DLG1_HUMAN (1-904): 0: 725: 100.00		DLG3_HUMAN (162-247): 4.16e-11: 68: 22.58
+	Rn
		677787 DLG1_RAT (1-904): 0: 701: 92.54		DLG4_RAT (111-248): 3.3e-16: 84.2: 18.62
+	Mm
		1113136 Q3UP61_MOUSE (1-904): 0: 700: 92.38		DLG4_MOUSE (111-248): 3.45e-16: 84.2: 18.62
+	Rn
		1144014 DLG1_RAT (1-904): 0: 701: 92.54		DLG2_RAT (153-253): 4.86e-15: 80.7: 18.58
+	Rn
		1144010 DLG1_RAT (1-904): 0: 701: 92.54		DLG3_RAT (130-247): 1.58e-11: 69.2: 20.80
+	Rn
		677790 DLG3_RAT (99-904): 0: 590: 64.57		DLG4_RAT (111-248): 3.3e-16: 84.2: 18.62
+	Mm
		936180 DLG3_MOUSE (99-904): 0: 589: 64.69		DLG4_MOUSE (111-248): 3.45e-16: 84.2: 18.62
+	Mm
		936188 DLG3_MOUSE (99-904): 0: 589: 64.69		DLG2_MOUSE (153-253): 4.74e-15: 80.7: 18.58
+	Hs
		942364 DLG3_HUMAN (139-904): 0: 585: 66.28		DLG4_HUMAN (111-248): 3.57e-16: 84.2: 18.62