Protein: EIF3M
Eukaryotic translation initiation factor 3 subunit M (eIF3m) (Fetal lung protein B5) (hFL-B5) (PCI domain-containing protein 1)

Gene: EIF3M
Organism: Homo sapiens
Interactions: 178
UniProt ID: Q7L2H7

Gene Ontology (top 5):
GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005852 - eukaryotic translation initiation factor 3 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

124889

EIF3F
Eukaryotic translation initiation factor 3 subunit F

13

20

Small-scale

0.983

High

177046

EIF3H
Eukaryotic translation initiation factor 3 subunit H

11

20

Small-scale

0.979

High

1049586

EIF3A
Eukaryotic translation initiation factor 3 subunit A

8

2

Small-scale

0.969

High

888389

EIF3E
Eukaryotic translation initiation factor 3 subunit E

7

4

Small-scale

0.964

High

1184160

EIF3K
Eukaryotic translation initiation factor 3 subunit K

7

1

Small-scale

0.964

High

1184169

EIF3L
Eukaryotic translation initiation factor 3 subunit L

7

1

Small-scale

0.964

High

1184145

EIF3C
Eukaryotic translation initiation factor 3 subunit C

6

3

Small-scale

0.944

High

78310

EIFCL
Eukaryotic translation initiation factor 3 subunit C-like protein

4

3

High-throughput

0.903

High

122044

PSD12
26S proteasome non-ATPase regulatory subunit 12

3

20

High-throughput

0.871

High

879281

EIF3B
Eukaryotic translation initiation factor 3 subunit B

7

3

Small-scale

0.747

High

275900

EIF3G
Eukaryotic translation initiation factor 3 subunit G

6

1

Small-scale

0.733

High

1032114

EIF3I
Eukaryotic translation initiation factor 3 subunit I

6

2

Small-scale

0.733

High

176809

EIF3D
Eukaryotic translation initiation factor 3 subunit D

7

0

Small-scale

0.713

High

1173842

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

3

2

High-throughput

0.667

High

1051881

IF4A2
Eukaryotic initiation factor 4A-II

3

1

High-throughput

0.650

High

319894

HERC2
E3 ubiquitin-protein ligase HERC2

3

4

Small-scale

0.633

High

892837

IF4A1
Eukaryotic initiation factor 4A-I

2

2

High-throughput

0.628

High

418399

NPM
Nucleophosmin

2

1

High-throughput

0.611

High

586822

CSK22
Casein kinase II subunit alpha'

2

6

High-throughput

0.611

High

934274

CSK21
Casein kinase II subunit alpha

2

7

High-throughput

0.611

High

347151

MYC
Myc proto-oncogene protein

3

1

High-throughput

0.585

High

979933

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

2

1

Small-scale

0.584

High

1184156

ANLN
Anillin

2

1

High-throughput

0.584

High

369892

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

592338

RAB5A
Ras-related protein Rab-5A

2

1

High-throughput

0.571

High

1184143

SRPK1
SRSF protein kinase 1

1

2

High-throughput

0.569

High

276034

EIF3J
Eukaryotic translation initiation factor 3 subunit J

2

0

Small-scale

0.569

High

1184159

ABI3
ABI gene family member 3

2

1

High-throughput

0.553

High

235087

DOK2
Docking protein 2

2

0

High-throughput

0.547

High

388543

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.541

High

403267

LA
Lupus La protein

1

2

High-throughput

0.536

High

529324

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

717960

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.536

High

780731

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

1

High-throughput

0.536

High

828812

SRP09
Signal recognition particle 9 kDa protein

1

1

High-throughput

0.536

High

873853

IF5
Eukaryotic translation initiation factor 5

1

1

High-throughput

0.536

High

897763

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.536

High

929527

RACK1
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.536

High

984617

CALD1
Caldesmon

1

1

High-throughput

0.536

High

1077001

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.536

High

1184139

AURKB
Aurora kinase B

1

2

High-throughput

0.536

High

1184140

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.536

High

1184157

DDX21
Nucleolar RNA helicase 2

1

1

High-throughput

0.536

High

1184162

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.536

High

1184167

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.536

High

1159167

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.517

High

239598

EIF1B
Eukaryotic translation initiation factor 1b

1

2

High-throughput

0.515

High

283553

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.513

High

417001

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.513

High

447962

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

545874

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

0

High-throughput

0.513

High

736542

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

739752

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

806060

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

840976

MAP2
Methionine aminopeptidase 2

1

0

High-throughput

0.513

High

907988

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

911424

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

923079

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

951616

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

1019810

ILF3
Interleukin enhancer-binding factor 3

1

0

High-throughput

0.513

High

1053901

CAPR1
Caprin-1

1

0

High-throughput

0.513

High

1184119

GSTA5
Glutathione S-transferase A5

1

0

High-throughput

0.513

High

1184170

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.513

High

1184171

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.513

High

395023

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

1184123

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

2

Small-scale

0.501

High

452821

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

643363

HMGB2
High mobility group protein B2

1

2

High-throughput

0.489

High

726899

FUS
RNA-binding protein FUS

1

2

High-throughput

0.489

High

996729

SSRP1
FACT complex subunit SSRP1

1

2

High-throughput

0.489

High

1184129

PSD4
PH and SEC7 domain-containing protein 4

1

2

High-throughput

0.489

High

1184146

RBM42
RNA-binding protein 42

1

1

High-throughput

0.489

High

966427

EXOSX
Exosome complex component 10

1

0

High-throughput

0.486

High

125543

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.479

High

148981

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

203382

IF4G3
Eukaryotic translation initiation factor 4 gamma 3

1

1

High-throughput

0.479

High

227870

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

386988

P53
Cellular tumor antigen p53

1

1

Small-scale

0.479

High

504295

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

739999

TGFR2
TGF-beta receptor type-2

1

1

High-throughput

0.479

High

779640

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

813572

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.479

High

845934

RB27A
Ras-related protein Rab-27A

1

1

High-throughput

0.479

High

870837

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

High-throughput

0.479

High

908737

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

998838

EP300
Histone acetyltransferase p300

1

5

High-throughput

0.479

High

1030320

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.479

High

1035846

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1038217

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

1

High-throughput

0.479

High

1050230

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

3

High-throughput

0.479

High

1061479

CUL7
Cullin-7

1

3

High-throughput

0.479

High

1064434

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1116347

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

1146548

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1148648

VIR
Protein virilizer homolog

1

4

High-throughput

0.479

High

1184121

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.479

High

1184124

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.479

High

1184126

DDX60
Probable ATP-dependent RNA helicase DDX60

1

1

High-throughput

0.479

High

1184130

CSK23
Casein kinase II subunit alpha 3

1

6

High-throughput

0.479

High

1184133

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

1184138

OPTN
Optineurin

1

2

High-throughput

0.479

High

1184141

SNX27
Sorting nexin-27

1

4

High-throughput

0.479

High

1184152

ECT2
Protein ECT2

1

2

High-throughput

0.479

High

1184155

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1184161

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1184163

TNIK
TRAF2 and NCK-interacting protein kinase

1

3

High-throughput

0.479

High

1184165

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.479

High

1184166

UBQL1
Ubiquilin-1

1

11

High-throughput

0.479

High

1184174

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

1184175

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.479

High

607679

NDKB
Nucleoside diphosphate kinase B

1

0

High-throughput

0.458

High

618652

IF4B
Eukaryotic translation initiation factor 4B

1

0

Small-scale

0.458

High

640519

DDX6
Probable ATP-dependent RNA helicase DDX6

1

0

High-throughput

0.458

High

719530

MERL
Merlin

1

0

High-throughput

0.458

High

896477

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.458

High

961174

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1184122

SLN11
Schlafen family member 11

1

0

Small-scale

0.458

High

1184125

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.458

High

1184136

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1184137

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

1184144

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1184158

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

1184168

ANGE1
Protein angel homolog 1

1

0

High-throughput

0.458

High

1184172

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

0

High-throughput

0.458

High

1184173

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

374434

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.445

High

438301

HS90B
Heat shock protein HSP 90-beta

1

2

Small-scale

0.445

High

497231

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

532563

TCTP
Translationally-controlled tumor protein

1

1

Small-scale

0.445

High

1130246

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

1153268

PKHA7
Pleckstrin homology domain-containing family A member 7

1

5

High-throughput

0.445

High

1184147

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

1

High-throughput

0.445

High

244602

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.437

High

266377

TAD2A
Transcriptional adapter 2-alpha

1

1

High-throughput

0.437

High

294967

RECQ4
ATP-dependent DNA helicase Q4

1

4

High-throughput

0.437

High

303322

HEXI1
Protein HEXIM1

1

1

High-throughput

0.437

High

351762

SOMA
Somatotropin

1

1

High-throughput

0.437

High

380311

HG2A
HLA class II histocompatibility antigen gamma chain

1

1

High-throughput

0.437

High

385059

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

553032

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

651535

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

720774

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

749615

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.437

High

824136

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.437

High

1038243

4EBP2
Eukaryotic translation initiation factor 4E-binding protein 2

1

1

High-throughput

0.437

High

1139105

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.437

High

1170546

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1184118

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.437

High

1184120

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1184134

ESR2
Estrogen receptor beta

1

6

High-throughput

0.437

High

1184135

TP4A1
Protein tyrosine phosphatase type IVA 1

1

1

High-throughput

0.437

High

1184150

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

1184154

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.437

High

1124538

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.426

High

402188

JUN
Transcription factor Jun

1

6

High-throughput

0.407

High

1184153

GPBL1
Vasculin-like protein 1

2

0

High-throughput

0.328

High

275346

ZMY10
Zinc finger MYND domain-containing protein 10

2

0

High-throughput

0.316

High

1168461

ZN783
Zinc finger protein 783

2

0

High-throughput

0.316

High

1184128

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

0

High-throughput

0.316

High

509039

TOP2A
DNA topoisomerase 2-alpha

1

0

High-throughput

0.279

Low

830990

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.279

Low

1054399

RBM39
RNA-binding protein 39

1

0

High-throughput

0.279

Low

1184132

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.279

Low

1184142

RBM14
RNA-binding protein 14

1

0

High-throughput

0.279

Low

1184164

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.279

Low

100894

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

338615

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.249

Low

815263

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.249

Low

903328

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

929773

KCNJ2
Inward rectifier potassium channel 2

1

0

Small-scale

0.249

Low

1184127

CMTR1
Cap-specific mRNA

1

0

High-throughput

0.249

Low

1184149

ARP6
Actin-related protein 6

1

0

High-throughput

0.249

Low

1184151

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

0

High-throughput

0.249

Low

484155

CALM3
Calmodulin-3

1

0

High-throughput

0.232

Low

596577

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.232

Low

1134727

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low

1184131

TB22A
TBC1 domain family member 22A

1

0

Small-scale

0.232

Low

1184148

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024