Protein: TRI32
E3 ubiquitin-protein ligase TRIM32 (EC 2.3.2.27) (72 kDa Tat-interacting protein) (RING-type E3 ubiquitin transferase TRIM32) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)

Gene: TRI32, TRIM32
Organism: Homo sapiens
Interactions: 202
UniProt ID: Q13049

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000209 - protein polyubiquitination
GO:0001894 - tissue homeostasis
GO:0003713 - transcription coactivator activity
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1093343

TRI32
E3 ubiquitin-protein ligase TRIM32

11

17

Small-scale

0.978

High

957724

UBE2N
Ubiquitin-conjugating enzyme E2 N

6

20

Small-scale

0.958

High

906652

UB2D1
Ubiquitin-conjugating enzyme E2 D1

5

20

Small-scale

0.917

High

1093448

UBQL1
Ubiquilin-1

4

12

High-throughput

0.911

High

1093345

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

4

20

Small-scale

0.906

High

1093429

AKTIP
AKT-interacting protein

4

20

High-throughput

0.905

High

909311

UB2E1
Ubiquitin-conjugating enzyme E2 E1

4

20

Small-scale

0.896

High

957068

UB2D3
Ubiquitin-conjugating enzyme E2 D3

4

20

Small-scale

0.885

High

507901

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

17

Small-scale

0.845

High

1093443

UBQL2
Ubiquilin-2

3

12

High-throughput

0.843

High

982174

UB2D2
Ubiquitin-conjugating enzyme E2 D2

3

20

Small-scale

0.840

High

1093365

UBE2U
Ubiquitin-conjugating enzyme E2 U

2

20

High-throughput

0.834

High

571952

TRI27
Zinc finger protein RFP

2

16

Small-scale

0.791

High

1093402

UB2E2
Ubiquitin-conjugating enzyme E2 E2

2

20

Small-scale

0.767

High

1093439

ABI2
Abl interactor 2

9

5

Small-scale

0.760

High

1093437

UBQL4
Ubiquilin-4

1

15

High-throughput

0.752

High

1093416

TRIM5
Tripartite motif-containing protein 5

1

18

High-throughput

0.733

High

303325

PDE9A
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

8

0

High-throughput

0.726

High

1093357

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

20

Small-scale

0.713

High

1093398

DTBP1
Dysbindin

4

4

Small-scale

0.702

High

140245

SDCB1
Syntenin-1

4

5

High-throughput

0.698

High

1093379

STING
Stimulator of interferon genes protein

4

8

Small-scale

0.692

High

547953

UTER
Uteroglobin

5

0

High-throughput

0.689

High

1053653

PTN11
Tyrosine-protein phosphatase non-receptor type 11

3

4

High-throughput

0.676

High

1093364

SYT6
Synaptotagmin-6

3

3

High-throughput

0.675

High

1093377

KCTD9
BTB/POZ domain-containing protein KCTD9

3

6

High-throughput

0.675

High

1093383

CLIP4
CAP-Gly domain-containing linker protein 4

3

5

High-throughput

0.675

High

1093457

S23IP
SEC23-interacting protein

3

2

High-throughput

0.667

High

1093454

SRPRB
Signal recognition particle receptor subunit beta

3

3

High-throughput

0.667

High

1093390

PTCD2
Pentatricopeptide repeat-containing protein 2, mitochondrial

3

4

High-throughput

0.654

High

729792

1433B
14-3-3 protein beta/alpha

3

20

Small-scale

0.650

High

1093372

TRI72
Tripartite motif-containing protein 72

1

17

Small-scale

0.647

High

1093438

EXOC1
Exocyst complex component 1

3

0

High-throughput

0.646

High

927268

ATX1
Ataxin-1

2

2

High-throughput

0.643

High

131059

TULP2
Tubby-related protein 2

2

1

High-throughput

0.628

High

712196

TKT
Transketolase

2

2

High-throughput

0.628

High

1093453

CRYL1
Lambda-crystallin homolog

2

5

High-throughput

0.628

High

1093348

SQSTM
Sequestosome-1

2

10

Small-scale

0.624

High

1093354

IQCB1
IQ calmodulin-binding motif-containing protein 1

2

1

Small-scale

0.624

High

783253

TRI23
E3 ubiquitin-protein ligase TRIM23

1

5

Small-scale

0.621

High

1093392

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

20

Small-scale

0.621

High

1093446

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

18

Small-scale

0.621

High

241548

PRKN
E3 ubiquitin-protein ligase parkin

1

16

High-throughput

0.618

High

1093374

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.618

High

1093352

SEPT6
Septin-6

3

4

High-throughput

0.609

High

563704

CFTR
Cystic fibrosis transmembrane conductance regulator

2

3

High-throughput

0.608

High

170501

RAB7L
Ras-related protein Rab-7L1

2

8

High-throughput

0.606

High

933833

GEM
GTP-binding protein GEM

2

8

High-throughput

0.606

High

1009645

NGAL
Neutrophil gelatinase-associated lipocalin

2

1

High-throughput

0.606

High

1093385

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

10

High-throughput

0.606

High

1093399

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

4

High-throughput

0.606

High

1093408

DERL1
Derlin-1

2

2

High-throughput

0.606

High

1093433

NGB
Neuroglobin

2

0

High-throughput

0.602

High

730554

1433S
14-3-3 protein sigma

2

20

Small-scale

0.601

High

1049246

1433F
14-3-3 protein eta

2

20

Small-scale

0.584

High

1093351

CUL3
Cullin-3

2

17

Small-scale

0.584

High

254284

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

2

0

High-throughput

0.580

High

1093428

MOB1A
MOB kinase activator 1A

2

0

High-throughput

0.580

High

1093431

PELI2
E3 ubiquitin-protein ligase pellino homolog 2

2

0

High-throughput

0.580

High

1093450

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

905552

IRAK1
Interleukin-1 receptor-associated kinase 1

1

5

High-throughput

0.578

High

396017

ESR1
Estrogen receptor

2

18

High-throughput

0.571

High

406124

MYCN
N-myc proto-oncogene protein

1

7

Small-scale

0.561

High

761656

HSP74
Heat shock 70 kDa protein 4

1

11

Small-scale

0.561

High

1022703

XIAP
E3 ubiquitin-protein ligase XIAP

1

7

Small-scale

0.561

High

1093414

GLIS2
Zinc finger protein GLIS2

1

15

Small-scale

0.561

High

1093366

TTC23
Tetratricopeptide repeat protein 23

2

3

High-throughput

0.553

High

1093353

BTG3
Protein BTG3

1

1

High-throughput

0.541

High

1093420

RN208
RING finger protein 208

1

18

High-throughput

0.541

High

1093423

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

1

High-throughput

0.541

High

1093427

RNF41
E3 ubiquitin-protein ligase NRDP1

1

18

High-throughput

0.541

High

295577

CIB2
Calcium and integrin-binding family member 2

1

1

High-throughput

0.536

High

296772

ST1C4
Sulfotransferase 1C4

1

1

High-throughput

0.536

High

300649

KRT37
Keratin, type I cuticular Ha7

1

16

High-throughput

0.536

High

300752

KRT38
Keratin, type I cuticular Ha8

1

16

High-throughput

0.536

High

334178

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

3

High-throughput

0.536

High

346991

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

857436

NOTC1
Neurogenic locus notch homolog protein 1

1

3

High-throughput

0.536

High

1006243

CTG1B
Cancer/testis antigen 1

1

2

High-throughput

0.536

High

1041746

PPARD
Peroxisome proliferator-activated receptor delta

1

18

High-throughput

0.536

High

1093362

KLH22
Kelch-like protein 22

1

5

High-throughput

0.536

High

1093393

FBXW5
F-box/WD repeat-containing protein 5

1

2

High-throughput

0.536

High

1093396

KLH29
Kelch-like protein 29

1

6

High-throughput

0.536

High

1093405

DNJC7
DnaJ homolog subfamily C member 7

1

5

High-throughput

0.536

High

1093406

TBA1C
Tubulin alpha-1C chain

1

16

High-throughput

0.536

High

1093413

DUS16
Dual specificity protein phosphatase 16

1

5

High-throughput

0.536

High

1093415

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

1093421

GHC2
Mitochondrial glutamate carrier 2

1

7

High-throughput

0.536

High

1093358

EREP1
Endosomal transmembrane epsin interactor 1

2

1

Small-scale

0.526

High

75473

B3KPU6
Pentatricopeptide repeat-containing protein 2, mitochondrial

1

4

High-throughput

0.515

High

191327

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.513

High

289771

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.513

High

1091918

SEC20
Vesicle transport protein SEC20

1

0

High-throughput

0.513

High

1093356

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.513

High

1093359

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.513

High

1093363

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1093384

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1093389

TP4AP
Short transient receptor potential channel 4-associated protein

1

0

High-throughput

0.513

High

1093401

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

1093407

ABHEA
Protein ABHD14A

1

0

High-throughput

0.513

High

1093411

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

1093455

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

327982

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

12

Small-scale

0.501

High

952140

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

12

Small-scale

0.501

High

1093382

PIAS4
E3 SUMO-protein ligase PIAS4

1

12

Small-scale

0.501

High

1093412

MLP3C
Microtubule-associated protein 1 light chain 3 gamma

1

12

Small-scale

0.501

High

1093418

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

12

Small-scale

0.501

High

1093419

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

12

Small-scale

0.501

High

1093425

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

12

Small-scale

0.501

High

1093456

PIAS3
E3 SUMO-protein ligase PIAS3

1

12

Small-scale

0.501

High

252677

TSN3
Tetraspanin-3

1

1

High-throughput

0.489

High

261490

B4GT2
Beta-1,4-galactosyltransferase 2

1

1

High-throughput

0.489

High

416611

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.489

High

690016

CRBB3
Beta-crystallin B3

1

1

High-throughput

0.489

High

1010460

EREP3
Protein ENTREP3

1

1

High-throughput

0.489

High

1093360

INF2
Inverted formin-2

1

1

High-throughput

0.489

High

1093400

LOXL4
Lysyl oxidase homolog 4

1

3

High-throughput

0.489

High

1093435

CRAC1
Cartilage acidic protein 1

1

3

High-throughput

0.489

High

1093449

NDRG2
Protein NDRG2

1

0

Small-scale

0.480

High

144137

F16P2
Fructose-1,6-bisphosphatase isozyme 2

1

1

Small-scale

0.479

High

186744

P73
Tumor protein p73

1

10

Small-scale

0.479

High

252859

EXOC3
Exocyst complex component 3

1

1

High-throughput

0.479

High

279149

ULK1
Serine/threonine-protein kinase ULK1

1

9

Small-scale

0.479

High

330923

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

341563

EYA4
Protein phosphatase EYA4

1

2

High-throughput

0.479

High

345062

RIGI
Antiviral innate immune response receptor RIG-I

1

15

Small-scale

0.479

High

371907

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

413737

P53
Cellular tumor antigen p53

1

10

Small-scale

0.479

High

461418

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

466658

GLI1
Zinc finger protein GLI1

1

13

Small-scale

0.479

High

468318

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

519998

ANDR
Androgen receptor

1

16

High-throughput

0.479

High

520569

RARA
Retinoic acid receptor alpha

1

17

Small-scale

0.479

High

521331

ARAF
Serine/threonine-protein kinase A-Raf

1

12

Small-scale

0.479

High

625806

RXRA
Retinoic acid receptor RXR-alpha

1

14

Small-scale

0.479

High

668577

APC
Adenomatous polyposis coli protein

1

7

Small-scale

0.479

High

690961

1433T
14-3-3 protein theta

1

20

Small-scale

0.479

High

827765

STAT3
Signal transducer and activator of transcription 3

1

6

Small-scale

0.479

High

830653

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

840693

RS27
Small ribosomal subunit protein eS27

1

2

High-throughput

0.479

High

861142

MAP1B
Microtubule-associated protein 1B

1

6

High-throughput

0.479

High

861590

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

7

Small-scale

0.479

High

888019

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

904660

MECP2
Methyl-CpG-binding protein 2

1

6

High-throughput

0.479

High

930870

HSP72
Heat shock-related 70 kDa protein 2

1

10

High-throughput

0.479

High

966259

1433G
14-3-3 protein gamma

1

20

Small-scale

0.479

High

971465

1433E
14-3-3 protein epsilon

1

4

Small-scale

0.479

High

990165

1433Z
14-3-3 protein zeta/delta

1

20

Small-scale

0.479

High

1028173

MDM2
E3 ubiquitin-protein ligase Mdm2

1

5

Small-scale

0.479

High

1035581

KIF23
Kinesin-like protein KIF23

1

16

High-throughput

0.479

High

1060161

B2CL1
Bcl-2-like protein 1

1

6

Small-scale

0.479

High

1090610

TRAF2
TNF receptor-associated factor 2

1

18

Small-scale

0.479

High

1093344

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

14

High-throughput

0.479

High

1093346

BIRC3
Baculoviral IAP repeat-containing protein 3

1

6

Small-scale

0.479

High

1093347

BIRC2
Baculoviral IAP repeat-containing protein 2

1

12

Small-scale

0.479

High

1093350

STIM1
Stromal interaction molecule 1

1

1

Small-scale

0.479

High

1093355

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

1093380

GOLI
E3 ubiquitin-protein ligase RNF130

1

6

High-throughput

0.479

High

1093391

B2CL2
Bcl-2-like protein 2

1

6

Small-scale

0.479

High

1093394

OTUL
Ubiquitin thioesterase otulin

1

1

Small-scale

0.479

High

1093395

ARMC5
Armadillo repeat-containing protein 5

1

5

High-throughput

0.479

High

1093403

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

1093409

CP250
Centrosome-associated protein CEP250

1

9

High-throughput

0.479

High

1093410

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

10

High-throughput

0.479

High

1093417

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

7

Small-scale

0.479

High

1093422

EPN3
Epsin-3

1

10

High-throughput

0.479

High

1093424

CHM4B
Charged multivesicular body protein 4b

1

5

High-throughput

0.479

High

1093426

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.479

High

1093430

ECT2
Protein ECT2

1

6

High-throughput

0.479

High

1093432

PIDD1
p53-induced death domain-containing protein 1

1

5

Small-scale

0.479

High

1093441

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

6

Small-scale

0.479

High

1093442

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1093445

XPO7
Exportin-7

1

6

High-throughput

0.479

High

1093447

FBW1B
F-box/WD repeat-containing protein 11

1

7

High-throughput

0.479

High

1093451

FBW1A
F-box/WD repeat-containing protein 1A

1

7

High-throughput

0.479

High

1093381

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.458

High

1093397

GASP2
G-protein coupled receptor-associated sorting protein 2

1

0

High-throughput

0.458

High

1093436

METL5
rRNA N(6)-adenosine-methyltransferase METTL5

1

0

Small-scale

0.458

High

1093440

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1093434

CASS4
Cas scaffolding protein family member 4

1

3

High-throughput

0.457

High

727559

SC6A4
Sodium-dependent serotonin transporter

1

1

High-throughput

0.445

High

1093349

TBB3
Tubulin beta-3 chain

1

9

High-throughput

0.445

High

1093361

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

2

High-throughput

0.445

High

1093367

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.445

High

1093375

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

2

High-throughput

0.445

High

1093376

TBA1A
Tubulin alpha-1A chain

1

16

High-throughput

0.445

High

1093388

MSPD2
Motile sperm domain-containing protein 2

1

0

High-throughput

0.426

High

541987

TOP1
DNA topoisomerase 1

1

2

Small-scale

0.408

High

943514

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

1

High-throughput

0.407

High

1093369

ZNT6
Zinc transporter 6

1

1

High-throughput

0.407

High

1093370

NPAL3
NIPA-like protein 3

1

1

High-throughput

0.407

High

1093373

PKHG7
Pleckstrin homology domain-containing family G member 7

1

7

High-throughput

0.407

High

1093378

NIPA1
Magnesium transporter NIPA1

1

1

High-throughput

0.407

High

1093452

S27A6
Long-chain fatty acid transport protein 6

1

3

High-throughput

0.407

High

1093444

PRAF1
Prenylated Rab acceptor protein 1

4

0

High-throughput

0.370

High

249308

G137B
Integral membrane protein GPR137B

2

0

High-throughput

0.316

High

1093386

FADS6
Fatty acid desaturase 6

2

0

High-throughput

0.316

High

1093371

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1093404

YI001
Uncharacterized protein FLJ30774

1

0

High-throughput

0.249

Low

1093368

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low

1093387

CI163
Uncharacterized protein C9orf163

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025