HitPredict

Interactor 1: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Interactor 2: CLTR2 (Q9NS75)
Cysteinyl leukotriene receptor 2 (CysLTR2) (G-protein coupled receptor GPCR21) (hGPCR21) (G-protein coupled receptor HG57) (HPN321)
Gene: CYSLTR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	24550280, 30126976, 26617989, 21525870
Identification Methods	phage display, p8 filamentous phage display, tandem affinity purification, ubiquitin reconstruction
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 904 Hs			1 346
+	Hs
		626682 DLG1_HUMAN (1-904): 0: 725: 100.00		ADA1D_HUMAN (41-316): 2.42e-66: 220: 16.62
+	Hs
		676802 DLG1_HUMAN (1-904): 0: 725: 100.00		SSR1_HUMAN (31-324): 6.72e-68: 219: 25.42
+	Hs
		1271030 DLG3_HUMAN (139-904): 0: 585: 66.28		CLTR2_HUMAN (1-346): 1.04e-70: 225: 100.00
+	Hs
		697561 PALS2_HUMAN (421-899): 2.36e-108: 346: 23.48		SSR3_HUMAN (1-338): 9.72e-69: 222: 25.36
+	Hs
		1329017 PALS2_HUMAN (421-899): 2.36e-108: 346: 23.48		P2Y12_HUMAN (20-321): 1.23e-30: 120: 29.26
+	Rn
		677767 DLG4_RAT (86-493): 2.93e-24: 111: 15.40		P2RY1_RAT (36-323): 3.49e-81: 253: 31.65
+	Hs
		159275 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		CLTR2_HUMAN (1-346): 1.04e-70: 225: 100.00
+	Rn
		677498 DLG4_RAT (86-493): 2.93e-24: 111: 15.40		SSR4_RAT (3-325): 6.07e-74: 235: 23.26
+	Hs
		159159 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		ADA1D_HUMAN (41-316): 2.42e-66: 220: 16.62
+	Rn
		495779 DLG4_RAT (86-493): 2.93e-24: 111: 15.40		ADRB2_RAT (6-342): 2.68e-72: 232: 17.12
+	Mm
		830267 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		SSR4_MOUSE (3-325): 3.65e-72: 230: 21.99
+	Hs
		942386 DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64		CLTR2_HUMAN (1-346): 1.04e-70: 225: 100.00
+	Mm
		676812 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		SSR1_MOUSE (31-324): 7.9e-70: 224: 25.42
+	Hs
		1050073 SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49		CLTR2_HUMAN (1-346): 1.04e-70: 225: 100.00
+	Mm
		676818 DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07		SSR2_MOUSE (7-345): 1.56e-68: 220: 24.64
+	Hs
		697554 SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49		SSR3_HUMAN (1-338): 9.72e-69: 222: 25.36
+	Mm
		830268 DLG2_MOUSE (393-627): 3.09e-21: 101: 24.48		SSR4_MOUSE (3-325): 3.65e-72: 230: 21.99
+	Hs
		626687 SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49		ADA1D_HUMAN (41-316): 2.42e-66: 220: 16.62
+	Mm
		676813 DLG2_MOUSE (393-627): 3.09e-21: 101: 24.48		SSR1_MOUSE (31-324): 7.9e-70: 224: 25.42
+	Hs
		697556 PALS1_HUMAN (1-397): 1.55e-20: 99.1: 14.74		SSR3_HUMAN (1-338): 9.72e-69: 222: 25.36