HitPredict

Interactor 1: STRN3 (Q13033)
Striatin-3 (Cell cycle autoantigen SG2NA) (S/G2 antigen)
Gene: STRN3

Interactor 2: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 797 Hs			1 487
+	Hs
		1022814 STRN3_HUMAN (1-797): 0: 626: 100.00		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		215222 STRN_HUMAN (19-797): 7.44e-179: 534: 62.45		STK4_HUMAN (1-487): 7.89e-170: 489: 100.00
+	Hs
		1022891 STRN3_HUMAN (1-797): 0: 626: 100.00		STK24_HUMAN (19-367): 1.13e-121: 364: 45.20
+	Hs
		131567 STRN3_HUMAN (1-797): 0: 626: 100.00		STK25_HUMAN (14-327): 8.86e-120: 359: 48.74
+	Hs
		1022877 STRN3_HUMAN (1-797): 0: 626: 100.00		STK26_HUMAN (25-390): 1.4e-119: 358: 43.82
+	Hs
		1022843 STRN3_HUMAN (1-797): 0: 626: 100.00		Q8NBY1_HUMAN (25-364): 1.87e-119: 357: 46.22
+	Hs
		215226 STRN_HUMAN (19-797): 7.44e-179: 534: 62.45		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		215296 STRN_HUMAN (19-797): 7.44e-179: 534: 62.45		STK24_HUMAN (19-367): 1.13e-121: 364: 45.20
+	Hs
		131539 STRN_HUMAN (19-797): 7.44e-179: 534: 62.45		STK25_HUMAN (14-327): 8.86e-120: 359: 48.74
+	Hs
		215282 STRN_HUMAN (19-797): 7.44e-179: 534: 62.45		STK26_HUMAN (25-390): 1.4e-119: 358: 43.82
+	Hs
		215253 STRN_HUMAN (19-797): 7.44e-179: 534: 62.45		Q8NBY1_HUMAN (25-364): 1.87e-119: 357: 46.22
+	Mm
		949415 STRN3_MOUSE (1-797): 0: 634: 95.86		TNIK_MOUSE (8-309): 1.1e-73: 254: 44.80
+	Hs
		72974 STRN3_HUMAN (1-797): 0: 626: 100.00		B4DR80_HUMAN (21-309): 6.11e-82: 261: 49.49
+	Hs
		1022881 STRN3_HUMAN (1-797): 0: 626: 100.00		TNIK_HUMAN (8-309): 2.1e-73: 254: 44.80
+	Hs
		1022840 STRN3_HUMAN (1-797): 0: 626: 100.00		MINK1_HUMAN (10-336): 5.97e-73: 252: 42.32
+	Hs
		131609 STRN4_HUMAN (14-797): 2.83e-156: 475: 47.88		STK25_HUMAN (14-327): 8.86e-120: 359: 48.74
+	Hs
		72970 STRN_HUMAN (19-797): 7.44e-179: 534: 62.45		B4DR80_HUMAN (21-309): 6.11e-82: 261: 49.49
+	Hs
		215286 STRN_HUMAN (19-797): 7.44e-179: 534: 62.45		TNIK_HUMAN (8-309): 2.1e-73: 254: 44.80
+	Hs
		215251 STRN_HUMAN (19-797): 7.44e-179: 534: 62.45		MINK1_HUMAN (10-336): 5.97e-73: 252: 42.32
+	Mm
		223076 STRN_MOUSE (19-797): 1.91e-176: 528: 62.58		TNIK_MOUSE (8-309): 1.1e-73: 254: 44.80