Interactor 1: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16

Interactor 2: APC1 (Q9H1A4)
Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)
Gene: ANAPC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.737

The method score is based on:

Property Details
Experiments 26496610, 28514442, 33961781, 35271311, 20360068, 11076961
Identification Methods affinity chromatography technology, biochemical, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0031145 - anaphase-promoting complex-dependent catabolic process
and 3 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 620
Hs

1 1944
+ Hs
+ Hs
+ Hs
+ At
+ At
+ At
+ Sp
+ Sp
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024