Protein: PEBB
Core-binding factor subunit beta (CBF-beta) (Polyomavirus enhancer-binding protein 2 beta subunit) (PEA2-beta) (PEBP2-beta) (SL3-3 enhancer factor 1 subunit beta) (SL3/AKV core-binding factor beta subunit)

Gene: PEBB, CBFB
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q13951

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000209 - protein polyubiquitination
GO:0001649 - osteoblast differentiation
GO:0003713 - transcription coactivator activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

964325

RUNX1
Runt-related transcription factor 1

20

8

Small-scale

0.988

High

1045122

RUNX3
Runt-related transcription factor 3

6

8

Small-scale

0.942

High

1047408

RUNX2
Runt-related transcription factor 2

5

8

Small-scale

0.922

High

1047454

CUL5
Cullin-5

6

1

Small-scale

0.842

High

542012

ETS1
Protein C-ets-1

1

1

High-throughput

0.618

High

1041314

CUL2
Cullin-2

1

1

High-throughput

0.618

High

1047436

PEBB
Core-binding factor subunit beta

1

1

High-throughput

0.618

High

1047440

ELOC
Elongin-C

3

0

Small-scale

0.613

High

670884

GFRP
GTP cyclohydrolase 1 feedback regulatory protein

2

0

High-throughput

0.602

High

1047468

RBX2
RING-box protein 2

2

1

Small-scale

0.595

High

886927

T2R41
Taste receptor type 2 member 41

2

0

High-throughput

0.585

High

1033640

IKZF1
DNA-binding protein Ikaros

2

2

Small-scale

0.584

High

1047471

IKZF3
Zinc finger protein Aiolos

2

2

Small-scale

0.584

High

1047458

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

2

0

High-throughput

0.559

High

1047441

ELOB
Elongin-B

2

0

Small-scale

0.547

High

717805

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.536

High

1021072

FOXF2
Forkhead box protein F2

1

1

High-throughput

0.536

High

1047453

HS105
Heat shock protein 105 kDa

1

2

High-throughput

0.536

High

64054

AQ12B
Aquaporin-12B

1

0

High-throughput

0.513

High

274091

XRP2
Protein XRP2

1

0

High-throughput

0.513

High

346745

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.513

High

1047437

LRC32
Transforming growth factor beta activator LRRC32

1

0

High-throughput

0.513

High

1047443

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

1047474

NIP7
60S ribosome subunit biogenesis protein NIP7 homolog

1

0

High-throughput

0.513

High

871563

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.493

High

1047465

INT13
Integrator complex subunit 13

1

0

High-throughput

0.493

High

320852

HS74L
Heat shock 70 kDa protein 4L

1

2

High-throughput

0.489

High

714221

HSP74
Heat shock 70 kDa protein 4

1

2

High-throughput

0.489

High

1047448

SESQ1
Sesquipedalian-1

1

2

High-throughput

0.489

High

1047464

COPRS
Coordinator of PRMT5 and differentiation stimulator

1

0

Small-scale

0.480

High

312601

ARI2
E3 ubiquitin-protein ligase ARIH2

1

1

High-throughput

0.479

High

317966

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

1

High-throughput

0.479

High

394697

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.479

High

401980

JUN
Transcription factor Jun

1

1

High-throughput

0.479

High

569707

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

668672

PML
Protein PML

1

1

High-throughput

0.479

High

831308

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.479

High

921258

RBX1
E3 ubiquitin-protein ligase RBX1

1

1

High-throughput

0.479

High

1021105

FOXC1
Forkhead box protein C1

1

1

High-throughput

0.479

High

1029403

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

1047470

IKZF2
Zinc finger protein Helios

1

2

High-throughput

0.479

High

1047476

ARI1
E3 ubiquitin-protein ligase ARIH1

1

1

High-throughput

0.479

High

118301

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

124207

TAF4
Transcription initiation factor TFIID subunit 4

1

0

High-throughput

0.458

High

177292

HDAC3
Histone deacetylase 3

1

0

High-throughput

0.458

High

214262

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

244417

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

253978

MTG16
Protein CBFA2T3

1

0

Small-scale

0.458

High

261506

NCOR1
Nuclear receptor corepressor 1

1

0

High-throughput

0.458

High

324392

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

376235

ANXA1
Annexin A1

1

0

High-throughput

0.458

High

545973

MYOD1
Myoblast determination protein 1

1

0

Small-scale

0.458

High

610396

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

610726

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

0

High-throughput

0.458

High

717072

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

734437

TCF7
Transcription factor 7

1

0

High-throughput

0.458

High

790395

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

799100

NKX21
Homeobox protein Nkx-2.1

1

0

High-throughput

0.458

High

801878

RECQ1
ATP-dependent DNA helicase Q1

1

0

High-throughput

0.458

High

835060

TSC2
Tuberin

1

0

High-throughput

0.458

High

838826

EMD
Emerin

1

0

High-throughput

0.458

High

852920

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

High-throughput

0.458

High

867698

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

974068

DYST
Dystonin

1

0

High-throughput

0.458

High

974557

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.458

High

975247

KMT2A
Histone-lysine N-methyltransferase 2A

1

0

Small-scale

0.458

High

977232

CEBPZ
CCAAT/enhancer-binding protein zeta

1

0

High-throughput

0.458

High

980749

TLE3
Transducin-like enhancer protein 3

1

0

High-throughput

0.458

High

1047439

HLTF
Helicase-like transcription factor

1

0

High-throughput

0.458

High

1047442

NEDD8
NEDD8

1

0

High-throughput

0.458

High

1047445

S4A10
Sodium-driven chloride bicarbonate exchanger

1

0

High-throughput

0.458

High

1047450

DCA11
DDB1- and CUL4-associated factor 11

1

0

High-throughput

0.458

High

1047451

PDC6I
Programmed cell death 6-interacting protein

1

0

High-throughput

0.458

High

1047455

RBM14
RNA-binding protein 14

1

0

High-throughput

0.458

High

1047457

HTF4
Transcription factor 12

1

0

High-throughput

0.458

High

1047459

BC11B
B-cell lymphoma/leukemia 11B

1

0

High-throughput

0.458

High

1047461

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

0

High-throughput

0.458

High

1047472

AKP8L
A-kinase anchor protein 8-like

1

0

High-throughput

0.458

High

1047475

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

0

High-throughput

0.458

High

1047462

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1047456

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

738754

SPB5
Serpin B5

2

0

High-throughput

0.318

High

1047449

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

2

0

High-throughput

0.318

High

1047460

S2532
Solute carrier family 25 member 32

2

0

High-throughput

0.318

High

1047467

HPBP1
Hsp70-binding protein 1

2

0

High-throughput

0.318

High

895073

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.292

High

393785

SCG1
Secretogranin-1

1

0

High-throughput

0.282

High

445781

ACM5
Muscarinic acetylcholine receptor M5

1

0

High-throughput

0.282

High

271927

FCN3
Ficolin-3

1

0

High-throughput

0.279

Low

1047446

FBW12
F-box/WD repeat-containing protein 12

1

0

High-throughput

0.279

Low

1047447

LHPL4
LHFPL tetraspan subfamily member 4 protein

1

0

High-throughput

0.279

Low

1047452

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

0

High-throughput

0.279

Low

1047466

RBM28
RNA-binding protein 28

1

0

High-throughput

0.279

Low

1047469

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

High-throughput

0.279

Low

164886

SC16A
Protein transport protein Sec16A

1

0

High-throughput

0.249

Low

242933

GAS7
Growth arrest-specific protein 7

1

0

High-throughput

0.249

Low

503284

MTAP2
Microtubule-associated protein 2

1

0

High-throughput

0.249

Low

590911

BTF3
Transcription factor BTF3

1

0

High-throughput

0.249

Low

599572

SYT1
Synaptotagmin-1

1

0

High-throughput

0.249

Low

671813

PDIA3
Protein disulfide-isomerase A3

1

0

High-throughput

0.249

Low

933441

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.249

Low

970673

CO7A1
Collagen alpha-1(VII) chain

1

0

High-throughput

0.249

Low

1030227

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.249

Low

1047438

SPRL1
SPARC-like protein 1

1

0

High-throughput

0.249

Low

1047463

ABC3G
DNA dC->dU-editing enzyme APOBEC-3G

1

0

Small-scale

0.249

Low

1047473

UBP18
Ubl carboxyl-terminal hydrolase 18

1

0

Small-scale

0.249

Low

1047477

YTHD2
YTH domain-containing family protein 2

1

0

High-throughput

0.249

Low

1047444

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024