Protein: JAG2
Protein jagged-2 (Jagged2) (hJ2)

Gene: JAG2
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q9Y219

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001701 - in utero embryonic development
GO:0003016 - respiratory system process
GO:0005112 - Notch binding
GO:0005509 - calcium ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1232149

VASN
Vasorin

2

2

High-throughput

0.811

High

1047784

NOTC2
Neurogenic locus notch homolog protein 2

1

20

Small-scale

0.724

High

596547

CTLA4
Cytotoxic T-lymphocyte protein 4

1

1

High-throughput

0.691

High

607433

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

1

High-throughput

0.691

High

688648

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

12

High-throughput

0.691

High

841598

I12R1
Interleukin-12 receptor subunit beta-1

1

2

High-throughput

0.691

High

1360048

OIT3
Oncoprotein-induced transcript 3 protein

1

18

High-throughput

0.691

High

1363166

CLC2B
C-type lectin domain family 2 member B

1

12

High-throughput

0.691

High

1392401

PGCB
Brevican core protein

1

4

High-throughput

0.691

High

1419507

CNTP3
Contactin-associated protein-like 3

1

19

High-throughput

0.691

High

1430747

SIRPD
Signal-regulatory protein delta

1

1

High-throughput

0.691

High

1460479

BTNL2
Butyrophilin-like protein 2

1

5

High-throughput

0.691

High

1490437

ST14
Suppressor of tumorigenicity 14 protein

1

9

High-throughput

0.691

High

1348910

PLPR1
Phospholipid phosphatase-related protein type 1

3

1

High-throughput

0.667

High

1448854

TMPS4
Transmembrane protease serine 4

1

12

High-throughput

0.665

High

857599

NOTC1
Neurogenic locus notch homolog protein 1

1

19

Small-scale

0.647

High

1461969

NOTC3
Neurogenic locus notch homolog protein 3

1

20

Small-scale

0.647

High

476521

STS
Steryl-sulfatase

2

3

High-throughput

0.628

High

1349414

ADA32
Disintegrin and metalloproteinase domain-containing protein 32

2

8

High-throughput

0.628

High

568022

PRG2
Bone marrow proteoglycan

1

11

High-throughput

0.618

High

628475

KLK2
Kallikrein-2

1

9

High-throughput

0.618

High

663579

CMA1
Chymase

1

8

High-throughput

0.618

High

1177905

CL12B
C-type lectin domain family 12 member B

1

10

High-throughput

0.618

High

1432129

KLK15
Kallikrein-15

1

9

High-throughput

0.618

High

1286958

TM11B
Transmembrane protease serine 11B

1

10

High-throughput

0.618

High

1187230

CC50B
Cell cycle control protein 50B

2

0

High-throughput

0.602

High

1462138

AT1B4
Protein ATP1B4

2

0

High-throughput

0.585

High

1217778

GFI1B
Zinc finger protein Gfi-1b

1

17

High-throughput

0.573

High

1417989

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

20

High-throughput

0.541

High

64399

CDHR4
Cadherin-related family member 4

1

3

High-throughput

0.536

High

65957

LIRA5
Leukocyte immunoglobulin-like receptor subfamily A member 5

1

4

High-throughput

0.536

High

164782

GDF8
Growth/differentiation factor 8

1

5

High-throughput

0.536

High

231351

EFNA2
Ephrin-A2

1

5

High-throughput

0.536

High

341379

ECEL1
Endothelin-converting enzyme-like 1

1

2

High-throughput

0.536

High

480935

LEG1
Galectin-1

1

10

High-throughput

0.536

High

597018

TSHR
Thyrotropin receptor

1

4

High-throughput

0.536

High

699263

CALX
Calnexin

1

4

High-throughput

0.536

High

942170

WNT3A
Protein Wnt-3a

1

12

High-throughput

0.536

High

1102965

ITAD
Integrin alpha-D

1

1

High-throughput

0.536

High

1245946

BRID5
BRICHOS domain-containing protein 5

1

1

High-throughput

0.536

High

1248598

LYPD4
Ly6/PLAUR domain-containing protein 4

1

1

High-throughput

0.536

High

1324289

LYPD1
Ly6/PLAUR domain-containing protein 1

1

2

High-throughput

0.536

High

1382095

T106A
Transmembrane protein 106A

1

1

High-throughput

0.536

High

1390903

ASIC4
Acid-sensing ion channel 4

1

1

High-throughput

0.536

High

1392023

PLPR2
Phospholipid phosphatase-related protein type 2

1

1

High-throughput

0.536

High

1461072

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

12

High-throughput

0.536

High

1490435

PCDB3
Protocadherin beta-3

1

1

High-throughput

0.536

High

426153

PPB1
Alkaline phosphatase, placental type

1

0

High-throughput

0.513

High

519680

LYAG
Lysosomal alpha-glucosidase

1

0

High-throughput

0.513

High

1333793

TM87A
Transmembrane protein 87A

1

0

High-throughput

0.513

High

1458487

P2RX2
P2X purinoceptor 2

1

0

High-throughput

0.513

High

139756

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

4

High-throughput

0.508

High

928368

ATN1
Atrophin-1

1

5

High-throughput

0.508

High

1383743

MIB2
E3 ubiquitin-protein ligase MIB2

1

20

Small-scale

0.501

High

885451

HXA1
Homeobox protein Hox-A1

1

8

High-throughput

0.494

High

1460486

MBD1
Methyl-CpG-binding domain protein 1

1

5

High-throughput

0.494

High

570724

EDN3
Endothelin-3

1

2

High-throughput

0.489

High

1103117

MFAP5
Microfibrillar-associated protein 5

1

3

High-throughput

0.489

High

1159281

ZNF74
Zinc finger protein 74

1

15

High-throughput

0.489

High

1249694

IGFL3
Insulin growth factor-like family member 3

1

4

High-throughput

0.489

High

1355973

NET5
Netrin-5

1

14

High-throughput

0.489

High

1360169

PATE1
Prostate and testis expressed protein 1

1

1

High-throughput

0.489

High

1460866

FBX2
F-box only protein 2

1

14

High-throughput

0.489

High

1490436

LIPG
Endothelial lipase

1

1

High-throughput

0.489

High

126879

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

189936

STX7
Syntaxin-7

1

5

High-throughput

0.479

High

218972

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

376109

RASK
GTPase KRas

1

15

High-throughput

0.479

High

631569

RAB5A
Ras-related protein Rab-5A

1

7

High-throughput

0.479

High

774712

BASI
Basigin

1

6

High-throughput

0.479

High

901109

RAB5C
Ras-related protein Rab-5C

1

7

High-throughput

0.479

High

978412

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

1041377

CAV1
Caveolin-1

1

3

High-throughput

0.479

High

1058729

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.479

High

1087345

STX4
Syntaxin-4

1

5

High-throughput

0.479

High

1114680

CUL3
Cullin-3

1

12

High-throughput

0.479

High

1145179

RAB35
Ras-related protein Rab-35

1

4

High-throughput

0.479

High

1159910

OCLN
Occludin

1

2

High-throughput

0.479

High

1323047

CXD3
Gap junction delta-3 protein

1

4

High-throughput

0.479

High

184755

ATX7
Ataxin-7

1

2

High-throughput

0.464

High

1249337

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

339055

GTR10
Solute carrier family 2, facilitated glucose transporter member 10

1

1

High-throughput

0.445

High

870433

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

1

High-throughput

0.445

High

1236380

MFSD5
Molybdate-anion transporter

1

1

High-throughput

0.445

High

1310983

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

4

High-throughput

0.445

High

1460377

SO3A1
Solute carrier organic anion transporter family member 3A1

1

2

High-throughput

0.445

High

327506

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.437

High

417855

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

418519

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.437

High

847749

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.437

High

895162

EMD
Emerin

1

1

High-throughput

0.437

High

951527

SC61B
Protein transport protein Sec61 subunit beta

1

3

High-throughput

0.437

High

1293212

TMM17
Transmembrane protein 17

1

3

High-throughput

0.437

High

1334065

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.437

High

1382009

CK052
Uncharacterized protein C11orf52

1

2

High-throughput

0.437

High

1383182

LRC59
Leucine-rich repeat-containing protein 59

1

4

High-throughput

0.437

High

1404284

SEC62
Translocation protein SEC62

1

2

High-throughput

0.437

High

1436365

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.437

High

1452728

ELOV5
Very long chain fatty acid elongase 5

1

4

High-throughput

0.437

High

1454865

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.437

High

1242274

NPAL3
NIPA-like protein 3

1

1

High-throughput

0.407

High

1363490

S39A7
Zinc transporter SLC39A7

1

4

High-throughput

0.407

High

1392502

TECT2
Tectonic-2

2

0

High-throughput

0.328

High

342699

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

1181036

DB136
Defensin beta 136

1

0

High-throughput

0.279

Low

1248813

LYZL1
Lysozyme-like protein 1

1

0

High-throughput

0.279

Low

1347309

FIBIN
Fin bud initiation factor homolog

1

0

High-throughput

0.279

Low

1439382

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.279

Low

1490434

UST
Uronyl 2-sulfotransferase

1

0

High-throughput

0.279

Low

1335263

RB8NL
RBBP8 N-terminal-like protein

1

0

High-throughput

0.249

Low

1450139

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1453929

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025