HitPredict

Interactor 1: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Interactor 2: MOB1B (Q7L9L4)
MOB kinase activator 1B (Mob1 homolog 1A) (Mob1A) (Mob1B) (Mps one binder kinase activator-like 1A)
Gene: MOB1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 37536630, 24255178, 22863277
Identification Methods proximity labelling technology, affinity chromatography technology, protein kinase assay, anti tag coimmunoprecipitation
Interaction Type physical association, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0035329 - hippo signaling
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 487
Hs

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Last updated: 15 Jul 2024