Protein: RBM6
RNA-binding protein 6 (Lung cancer antigen NY-LU-12) (Protein G16) (RNA-binding motif protein 6) (RNA-binding protein DEF-3)

Gene: RBM6
Organism: Homo sapiens
Interactions: 127
UniProt ID: P78332

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0006396 - RNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1005498

DDX23
Probable ATP-dependent RNA helicase DDX23

2

20

High-throughput

0.789

High

289500

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

20

High-throughput

0.691

High

608540

DDX5
Probable ATP-dependent RNA helicase DDX5

1

13

High-throughput

0.691

High

1005470

DDX42
ATP-dependent RNA helicase DDX42

1

13

High-throughput

0.691

High

1005469

ZCH18
Zinc finger CCCH domain-containing protein 18

3

17

High-throughput

0.675

High

485052

ROA1
Heterogeneous nuclear ribonucleoprotein A1

3

20

High-throughput

0.650

High

269105

MITF
Microphthalmia-associated transcription factor

2

1

High-throughput

0.628

High

854820

RECQ1
ATP-dependent DNA helicase Q1

1

20

High-throughput

0.618

High

1005447

DHX8
ATP-dependent RNA helicase DHX8

1

17

High-throughput

0.618

High

1005472

DHX40
Probable ATP-dependent RNA helicase DHX40

1

16

High-throughput

0.618

High

1005489

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

2

19

High-throughput

0.611

High

1005496

CDC5L
Cell division cycle 5-like protein

2

8

High-throughput

0.611

High

1005518

PRP19
Pre-mRNA-processing factor 19

2

16

High-throughput

0.611

High

775005

FUS
RNA-binding protein FUS

2

20

High-throughput

0.601

High

1005458

MARE2
Microtubule-associated protein RP/EB family member 2

3

3

High-throughput

0.597

High

385643

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

5

High-throughput

0.584

High

1005513

ZRAN1
Ubiquitin thioesterase ZRANB1

2

11

High-throughput

0.584

High

395879

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

687965

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.549

High

1005456

SF3B3
Splicing factor 3B subunit 3

1

4

High-throughput

0.541

High

163742

TCRG1
Transcription elongation regulator 1

1

7

High-throughput

0.536

High

212209

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

4

High-throughput

0.536

High

222467

PLRG1
Pleiotropic regulator 1

1

17

High-throughput

0.536

High

297960

SPF27
Pre-mRNA-splicing factor SPF27

1

1

High-throughput

0.536

High

477991

SNRPA
U1 small nuclear ribonucleoprotein A

1

20

High-throughput

0.536

High

541942

TOP1
DNA topoisomerase 1

1

4

High-throughput

0.536

High

765372

BMI1
Polycomb complex protein BMI-1

1

19

High-throughput

0.536

High

846232

MATR3
Matrin-3

1

14

High-throughput

0.536

High

909531

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

20

High-throughput

0.536

High

935488

MFAP1
Microfibrillar-associated protein 1

1

2

High-throughput

0.536

High

968251

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

10

High-throughput

0.536

High

1005437

ERH
Enhancer of rudimentary homolog

1

2

High-throughput

0.536

High

1005441

NCBP1
Nuclear cap-binding protein subunit 1

1

4

High-throughput

0.536

High

1005444

SNW1
SNW domain-containing protein 1

1

5

High-throughput

0.536

High

1005452

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.536

High

1005462

PRP8
Pre-mRNA-processing-splicing factor 8

1

4

High-throughput

0.536

High

1005474

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

7

High-throughput

0.536

High

1005479

ZBT44
Zinc finger and BTB domain-containing protein 44

1

2

High-throughput

0.536

High

1005483

CTCFL
Transcriptional repressor CTCFL

1

4

High-throughput

0.536

High

1005485

CTBL1
Beta-catenin-like protein 1

1

1

High-throughput

0.536

High

1005490

THOC1
THO complex subunit 1

1

1

High-throughput

0.536

High

1005494

RBM14
RNA-binding protein 14

1

18

High-throughput

0.536

High

1005495

ALS2
Alsin

1

4

High-throughput

0.536

High

1005501

PININ
Pinin

1

4

High-throughput

0.536

High

1005519

TR150
Thyroid hormone receptor-associated protein 3

1

13

High-throughput

0.536

High

1005520

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

9

High-throughput

0.536

High

1005457

TAF7
Transcription initiation factor TFIID subunit 7

1

0

High-throughput

0.518

High

1005439

STP2
Nuclear transition protein 2

1

0

High-throughput

0.513

High

1005454

PLEC
Plectin

1

0

High-throughput

0.493

High

1005461

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

0

High-throughput

0.493

High

1005443

GAGE5
G antigen 5

1

1

High-throughput

0.489

High

1005451

EMC2
ER membrane protein complex subunit 2

1

7

High-throughput

0.489

High

1005471

EPHX4
Epoxide hydrolase 4

1

2

High-throughput

0.489

High

1005476

EMC5
ER membrane protein complex subunit 5

1

2

High-throughput

0.489

High

1005497

FEM1A
Protein fem-1 homolog A

1

4

High-throughput

0.489

High

1005510

PAK5
Serine/threonine-protein kinase PAK 5

1

6

High-throughput

0.489

High

889549

CLK2
Dual specificity protein kinase CLK2

1

15

High-throughput

0.481

High

142929

NFIB
Nuclear factor 1 B-type

1

7

High-throughput

0.479

High

170078

AURKA
Aurora kinase A

1

10

High-throughput

0.479

High

349034

LATS1
Serine/threonine-protein kinase LATS1

1

7

High-throughput

0.479

High

370630

FOS
Protein c-Fos

1

6

High-throughput

0.479

High

371730

MYC
Myc proto-oncogene protein

1

18

High-throughput

0.479

High

406040

MYCN
N-myc proto-oncogene protein

1

17

High-throughput

0.479

High

413600

P53
Cellular tumor antigen p53

1

8

High-throughput

0.479

High

429707

JUN
Transcription factor Jun

1

9

High-throughput

0.479

High

473906

NFIC
Nuclear factor 1 C-type

1

9

High-throughput

0.479

High

798980

BRCA1
Breast cancer type 1 susceptibility protein

1

17

High-throughput

0.479

High

904581

MECP2
Methyl-CpG-binding protein 2

1

12

High-throughput

0.479

High

1005436

RBM6
RNA-binding protein 6

1

16

High-throughput

0.479

High

1005438

TF65
Transcription factor p65

1

5

High-throughput

0.479

High

1005442

NFIA
Nuclear factor 1 A-type

1

10

High-throughput

0.479

High

1005446

RBM39
RNA-binding protein 39

1

19

High-throughput

0.479

High

1005449

NFIX
Nuclear factor 1 X-type

1

10

High-throughput

0.479

High

1005453

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.479

High

1005459

ELAV1
ELAV-like protein 1

1

16

High-throughput

0.479

High

1005460

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

3

High-throughput

0.479

High

1005467

RHG22
Rho GTPase-activating protein 22

1

6

High-throughput

0.479

High

1005473

SMC5
Structural maintenance of chromosomes protein 5

1

15

High-throughput

0.479

High

1005475

SLX4
Structure-specific endonuclease subunit SLX4

1

11

High-throughput

0.479

High

1005477

SIR6
NAD-dependent protein deacylase sirtuin-6

1

8

High-throughput

0.479

High

1005480

PAPD5
Terminal nucleotidyltransferase 4B

1

3

High-throughput

0.479

High

1005486

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

4

High-throughput

0.479

High

1005487

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1005488

CELF1
CUGBP Elav-like family member 1

1

20

High-throughput

0.479

High

1005492

FUBP3
Far upstream element-binding protein 3

1

20

High-throughput

0.479

High

1005500

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.479

High

1005505

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

8

High-throughput

0.479

High

1005507

RNC
Ribonuclease 3

1

8

High-throughput

0.479

High

1005512

NXF1
Nuclear RNA export factor 1

1

5

High-throughput

0.479

High

1005521

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.479

High

442664

RB
Retinoblastoma-associated protein

1

1

High-throughput

0.445

High

529605

TAU
Microtubule-associated protein tau

1

18

High-throughput

0.445

High

1005448

CASP8
Caspase-8

1

1

High-throughput

0.445

High

1005478

SERB1
SERPINE1 mRNA-binding protein 1

1

4

High-throughput

0.445

High

657531

GCSP
Glycine dehydrogenase

1

4

High-throughput

0.437

High

977672

ACTA
Actin, aortic smooth muscle

1

5

High-throughput

0.437

High

1005445

KLF5
Krueppel-like factor 5

1

8

High-throughput

0.437

High

1005450

CUL7
Cullin-7

1

11

High-throughput

0.437

High

1005463

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.437

High

1005465

ASB18
Ankyrin repeat and SOCS box protein 18

1

4

High-throughput

0.437

High

1005468

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

2

High-throughput

0.437

High

1005484

ASB12
Ankyrin repeat and SOCS box protein 12

1

6

High-throughput

0.437

High

1005491

RN185
E3 ubiquitin-protein ligase RNF185

1

10

Small-scale

0.437

High

1005493

SNX27
Sorting nexin-27

1

6

High-throughput

0.437

High

1005499

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

8

High-throughput

0.437

High

1005502

TXNIP
Thioredoxin-interacting protein

1

10

Small-scale

0.437

High

1005503

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1005504

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

7

High-throughput

0.437

High

1005515

NUP50
Nuclear pore complex protein Nup50

1

4

High-throughput

0.437

High

1005517

HECD1
E3 ubiquitin-protein ligase HECTD1

1

14

High-throughput

0.437

High

1005511

CPNE7
Copine-7

1

0

High-throughput

0.426

High

109144

G4U4J3
Terminal nucleotidyltransferase 4B

1

2

High-throughput

0.407

High

1005455

PGFRL
Platelet-derived growth factor receptor-like protein

1

5

High-throughput

0.407

High

1005516

PNMA2
Paraneoplastic antigen Ma2

1

4

High-throughput

0.407

High

1005440

FGL1
Fibrinogen-like protein 1

3

0

High-throughput

0.347

High

1005514

NAGK
N-acetyl-D-glucosamine kinase

2

0

High-throughput

0.328

High

1005523

CEPT1
Choline/ethanolaminephosphotransferase 1

2

0

High-throughput

0.328

High

251881

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

0

High-throughput

0.279

Low

1005464

K0408
Uncharacterized protein KIAA0408

1

0

High-throughput

0.279

Low

1005506

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.279

Low

1005508

ACER3
Alkaline ceramidase 3

1

0

High-throughput

0.279

Low

1005509

TM45A
Transmembrane protein 45A

1

0

High-throughput

0.279

Low

1005522

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

1005481

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

1005466

T2R42
Taste receptor type 2 member 42

1

0

High-throughput

0.232

Low

1005482

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025