Interactor 1: TRI32 (Q13049)
E3 ubiquitin-protein ligase TRIM32 (EC 2.3.2.27) (72 kDa Tat-interacting protein) (RING-type E3 ubiquitin transferase TRIM32) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)
Gene: TRIM32

Interactor 2: TRI32 (Q13049)
E3 ubiquitin-protein ligase TRIM32 (EC 2.3.2.27) (72 kDa Tat-interacting protein) (RING-type E3 ubiquitin transferase TRIM32) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)
Gene: TRIM32

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 16816390, 25416956, 30884854, 32296183, 11331580, 17994549, 21628460, 19349376, 23444366, 22493164, unassigned1304
Identification Methods enzymatic study, two hybrid, pull down, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains NHL~NHL, zf-RING_UBOX~zf-RING_UBOX
Common GO terms GO:0000209 - protein polyubiquitination
GO:0001894 - tissue homeostasis
GO:0003713 - transcription coactivator activity
GO:0003723 - RNA binding
GO:0004842 - ubiquitin-protein transferase activity
and 52 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 653
Hs

1 653
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Last updated: 15 Jul 2024