HitPredict

Interactor 1: UBP4 (Q13107)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)
Gene: USP4

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	26411366, 30071870
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 488
+	Hs
		850131 UBP11_HUMAN (6-937): 0: 717: 44.60		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		850032 UBP11_HUMAN (6-937): 0: 717: 44.60		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		301427 UBP19_HUMAN (183-937): 6.87e-148: 474: 30.87		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		301388 UBP19_HUMAN (183-937): 6.87e-148: 474: 30.87		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1198261 UBP37_HUMAN (164-938): 7.6e-90: 309: 14.43		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1329994 UBP15_HUMAN (1-924): 0: 749: 58.17		Q9H368_HUMAN (212-429): 3.07e-78: 245: 51.80
+	Hs
		1038495 UBP37_HUMAN (164-938): 7.6e-90: 309: 14.43		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1163944 U17L2_HUMAN (737-935): 1.07e-56: 206: 26.50		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1174179 UBP43_HUMAN (488-663): 7.26e-13: 75: 6.22		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1038483 UBP43_HUMAN (488-663): 7.26e-13: 75: 6.22		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Mm
		1193546 UBP8_MOUSE (727-932): 8.66e-58: 218: 34.45		Q8CGC3_MOUSE (11-367): 2.52e-102: 332: 23.93