HitPredict

Interactor 1: CAF1B (Q13112)
Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7)
Gene: CHAF1B

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33306668
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 559 Hs			1 496
+	Dm
		1358859 WDS_DROME (2-97): 6.43e-15: 78.5: 23.47		FBXW7_DROME (20-496): 6.04e-89: 298: 17.46
+	Hs
		1309163 TBL1R_HUMAN (211-422): 1.4e-24: 109: 7.93		TBL1Y_HUMAN (99-430): 2.64e-70: 234: 16.20
+	Hs
		793026 KTNB1_HUMAN (59-549): 3.11e-36: 145: 16.60		LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68
+	Hs
		792935 LIS1_HUMAN (222-474): 9.92e-34: 134: 8.81		LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68
+	Mm
		925836 LIS1_MOUSE (222-474): 8.65e-34: 134: 8.81		LIS1_MOUSE (309-495): 5.38e-53: 185: 19.68
+	Hs
		245630 TBL1X_HUMAN (2-97): 2.19e-14: 78.1: 18.75		TBL1Y_HUMAN (99-430): 2.64e-70: 234: 16.20
+	Hs
		1346954 NLE1_HUMAN (329-440): 1.36e-17: 87.8: 10.71		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		1240442 POC1A_HUMAN (2-198): 1.48e-44: 164: 19.29		POC1B_HUMAN (31-259): 4.34e-30: 124: 13.19
+	Hs
		1016312 TBL3_HUMAN (11-372): 1.78e-20: 97.6: 16.59		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		792949 LIS1_HUMAN (222-474): 9.92e-34: 134: 8.81		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		903174 TBL3_HUMAN (11-372): 1.78e-20: 97.6: 16.59		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		903551 NLE1_HUMAN (329-440): 1.36e-17: 87.8: 10.71		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		903349 WDR5B_HUMAN (2-93): 5.07e-14: 75.4: 21.28		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		903077 WDR5_HUMAN (2-94): 9.73e-14: 74.3: 24.21		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Dm
		1358845 WDS_DROME (2-97): 6.43e-15: 78.5: 23.47		WDS_DROME (389-496): 1.28e-24: 106: 17.43
+	Hs
		245633 TBL1X_HUMAN (2-97): 2.19e-14: 78.1: 18.75		TBL1R_HUMAN (98-260): 6.38e-22: 100: 13.22
+	Hs
		903176 WDR5_HUMAN (2-94): 9.73e-14: 74.3: 24.21		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67