Protein: PSIP1
PC4 and SFRS1-interacting protein (CLL-associated antigen KW-7) (Dense fine speckles 70 kDa protein) (DFS 70) (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52)

Gene: PSIP1
Organism: Homo sapiens
Interactions: 177
UniProt ID: O75475

Gene Ontology (top 5):
GO:0000395 - mRNA 5'-splice site recognition
GO:0000791 - euchromatin
GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

283067

H31
Histone H3.1

5

20

Small-scale

0.928

High

128671

MEN1
Menin

3

3

Small-scale

0.847

High

283047

HDGF
Hepatoma-derived growth factor

3

11

High-throughput

0.847

High

283113

HDGR2
Hepatoma-derived growth factor-related protein 2

2

13

High-throughput

0.789

High

283062

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.754

High

283070

H33
Histone H3.3

2

20

High-throughput

0.754

High

283022

H2AZ
Histone H2A.Z

1

14

High-throughput

0.691

High

283102

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.691

High

259213

BRD4
Bromodomain-containing protein 4

4

20

High-throughput

0.676

High

283077

KMT2A
Histone-lysine N-methyltransferase 2A

3

11

Small-scale

0.660

High

283028

HMGA1
High mobility group protein HMG-I/HMG-Y

2

3

Small-scale

0.641

High

277480

H2AY
Core histone macro-H2A.1

1

20

High-throughput

0.618

High

283044

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.618

High

283127

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.618

High

283049

HMGA2
High mobility group protein HMGI-C

2

2

Small-scale

0.611

High

283021

PARP1
Poly [ADP-ribose] polymerase 1

2

20

High-throughput

0.611

High

283156

KMT2B
Histone-lysine N-methyltransferase 2B

2

8

Small-scale

0.594

High

283065

SUMO1
Small ubiquitin-related modifier 1

1

4

Small-scale

0.586

High

283005

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

10

High-throughput

0.584

High

283026

XRCC6
X-ray repair cross-complementing protein 6

2

9

High-throughput

0.584

High

283027

RFA2
Replication protein A 32 kDa subunit

2

3

High-throughput

0.584

High

283033

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

6

High-throughput

0.584

High

283037

RFA3
Replication protein A 14 kDa subunit

2

5

High-throughput

0.584

High

283052

FOXA1
Hepatocyte nuclear factor 3-alpha

2

5

High-throughput

0.584

High

283130

CDA7L
Cell division cycle-associated 7-like protein

2

1

Small-scale

0.584

High

283080

SRSF1
Serine/arginine-rich splicing factor 1

1

18

Small-scale

0.578

High

283134

CTIP
DNA endonuclease RBBP8

1

1

Small-scale

0.561

High

283066

CSK21
Casein kinase II subunit alpha

1

8

High-throughput

0.550

High

133071

FOXE1
Forkhead box protein E1

1

7

High-throughput

0.536

High

283012

NPM
Nucleophosmin

1

6

High-throughput

0.536

High

283019

VIME
Vimentin

1

1

High-throughput

0.536

High

283032

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.536

High

283042

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

4

High-throughput

0.536

High

283069

CBX1
Chromobox protein homolog 1

1

19

High-throughput

0.536

High

283072

FOXK2
Forkhead box protein K2

1

6

High-throughput

0.536

High

283093

NUMA1
Nuclear mitotic apparatus protein 1

1

5

High-throughput

0.536

High

283143

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

1

High-throughput

0.536

High

283146

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

1

High-throughput

0.536

High

283147

TF7L2
Transcription factor 7-like 2

1

17

High-throughput

0.536

High

283025

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.515

High

283039

SMBP2
DNA-binding protein SMUBP-2

1

1

High-throughput

0.515

High

283132

ASPP1
Apoptosis-stimulating of p53 protein 1

1

6

High-throughput

0.515

High

283133

SCAFB
Protein SCAF11

1

3

High-throughput

0.515

High

283002

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.513

High

283079

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.513

High

283101

MK06
Mitogen-activated protein kinase 6

1

3

High-throughput

0.508

High

185292

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

283014

SP1
Transcription factor Sp1

1

3

Small-scale

0.501

High

283023

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

283050

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

2

Small-scale

0.501

High

283054

CDC42
Cell division control protein 42 homolog

1

7

High-throughput

0.501

High

283126

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

4

High-throughput

0.501

High

283006

ESR1
Estrogen receptor

1

20

High-throughput

0.500

High

283109

TM214
Transmembrane protein 214

1

0

High-throughput

0.493

High

283122

YLAT2
Y+L amino acid transporter 2

1

1

High-throughput

0.489

High

132416

CDC7
Cell division cycle 7-related protein kinase

1

4

High-throughput

0.479

High

142756

NFIB
Nuclear factor 1 B-type

1

13

High-throughput

0.479

High

156768

CTRO
Citron Rho-interacting kinase

1

9

High-throughput

0.479

High

222579

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

240288

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

271767

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.479

High

279079

ULK1
Serine/threonine-protein kinase ULK1

1

2

High-throughput

0.479

High

282997

BAF
Barrier-to-autointegration factor

1

1

Small-scale

0.479

High

282999

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

283000

KI20A
Kinesin-like protein KIF20A

1

6

High-throughput

0.479

High

283001

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

19

High-throughput

0.479

High

283004

MYC
Myc proto-oncogene protein

1

13

High-throughput

0.479

High

283007

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.479

High

283008

MYCN
N-myc proto-oncogene protein

1

11

High-throughput

0.479

High

283009

HMGN1
Non-histone chromosomal protein HMG-14

1

1

High-throughput

0.479

High

283011

ENOA
Alpha-enolase

1

2

High-throughput

0.479

High

283015

RHOC
Rho-related GTP-binding protein RhoC

1

8

High-throughput

0.479

High

283016

HS90B
Heat shock protein HSP 90-beta

1

2

High-throughput

0.479

High

283017

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

4

High-throughput

0.479

High

283018

NFIC
Nuclear factor 1 C-type

1

16

High-throughput

0.479

High

283029

CEBPB
CCAAT/enhancer-binding protein beta

1

10

High-throughput

0.479

High

283031

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.479

High

283034

APEX1
DNA repair nuclease/redox regulator APEX1

1

8

High-throughput

0.479

High

283036

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

High-throughput

0.479

High

283038

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

283041

GATA4
Transcription factor GATA-4

1

3

High-throughput

0.479

High

283043

SOX2
Transcription factor SOX-2

1

16

High-throughput

0.479

High

283046

MECP2
Methyl-CpG-binding protein 2

1

12

High-throughput

0.479

High

283048

IMA5
Importin subunit alpha-5

1

4

High-throughput

0.479

High

283051

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

3

High-throughput

0.479

High

283056

RHOA
Transforming protein RhoA

1

8

High-throughput

0.479

High

283057

WDR5
WD repeat-containing protein 5

1

11

High-throughput

0.479

High

283058

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

283060

RS6
Small ribosomal subunit protein eS6

1

4

High-throughput

0.479

High

283061

H4
Histone H4

1

10

High-throughput

0.479

High

283063

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

283064

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

6

High-throughput

0.479

High

283068

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.479

High

283071

VIGLN
Vigilin

1

4

High-throughput

0.479

High

283074

EWS
RNA-binding protein EWS

1

3

High-throughput

0.479

High

283075

PO5F1
POU domain, class 5, transcription factor 1

1

4

High-throughput

0.479

High

283076

MECOM
Histone-lysine N-methyltransferase MECOM

1

3

High-throughput

0.479

High

283078

TF65
Transcription factor p65

1

5

High-throughput

0.479

High

283081

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.479

High

283082

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

18

High-throughput

0.479

High

283083

REST
RE1-silencing transcription factor

1

1

High-throughput

0.479

High

283084

CBX3
Chromobox protein homolog 3

1

19

High-throughput

0.479

High

283085

IKZF1
DNA-binding protein Ikaros

1

2

High-throughput

0.479

High

283086

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

283087

SQSTM
Sequestosome-1

1

4

High-throughput

0.479

High

283089

RBM39
RNA-binding protein 39

1

3

High-throughput

0.479

High

283091

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

19

High-throughput

0.479

High

283092

NFIX
Nuclear factor 1 X-type

1

14

High-throughput

0.479

High

283094

CUL7
Cullin-7

1

4

High-throughput

0.479

High

283095

TNIP1
TNFAIP3-interacting protein 1

1

13

High-throughput

0.479

High

283096

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.479

High

283097

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

283098

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.479

High

283099

RBBP5
Retinoblastoma-binding protein 5

1

11

High-throughput

0.479

High

283100

EZH2
Histone-lysine N-methyltransferase EZH2

1

10

High-throughput

0.479

High

283105

BRDT
Bromodomain testis-specific protein

1

20

High-throughput

0.479

High

283106

HABP4
Intracellular hyaluronan-binding protein 4

1

4

High-throughput

0.479

High

283108

RN123
E3 ubiquitin-protein ligase RNF123

1

8

High-throughput

0.479

High

283111

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

10

High-throughput

0.479

High

283112

POGZ
Pogo transposable element with ZNF domain

1

9

High-throughput

0.479

High

283114

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

283115

ZCH18
Zinc finger CCCH domain-containing protein 18

1

7

High-throughput

0.479

High

283116

SMC5
Structural maintenance of chromosomes protein 5

1

10

High-throughput

0.479

High

283118

SERB1
SERPINE1 mRNA-binding protein 1

1

4

High-throughput

0.479

High

283119

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

283120

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

283121

DNJC9
DnaJ homolog subfamily C member 9

1

5

High-throughput

0.479

High

283123

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

283124

KAT6A
Histone acetyltransferase KAT6A

1

20

High-throughput

0.479

High

283125

KAT5
Histone acetyltransferase KAT5

1

5

Small-scale

0.479

High

283128

SH3K1
SH3 domain-containing kinase-binding protein 1

1

4

High-throughput

0.479

High

283129

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

283131

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.479

High

283135

CP250
Centrosome-associated protein CEP250

1

7

High-throughput

0.479

High

283137

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.479

High

283138

PDIP3
Polymerase delta-interacting protein 3

1

4

High-throughput

0.479

High

283141

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

283145

PRD16
Histone-lysine N-methyltransferase PRDM16

1

3

High-throughput

0.479

High

283148

ANLN
Anillin

1

4

High-throughput

0.479

High

283149

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

6

High-throughput

0.479

High

283151

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

6

High-throughput

0.479

High

283152

DBF4A
Protein DBF4 homolog A

1

1

High-throughput

0.479

High

283153

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

283154

IKZF3
Zinc finger protein Aiolos

1

2

High-throughput

0.479

High

283157

TR150
Thyroid hormone receptor-associated protein 3

1

12

High-throughput

0.479

High

283158

ZN330
Zinc finger protein 330

1

7

High-throughput

0.479

High

283159

CD2AP
CD2-associated protein

1

4

High-throughput

0.479

High

283160

HCFC2
Host cell factor 2

1

1

High-throughput

0.479

High

283161

SETBP
SET-binding protein

1

1

Small-scale

0.479

High

283040

GDF5
Growth/differentiation factor 5

1

1

High-throughput

0.470

High

283013

LDHB
L-lactate dehydrogenase B chain

1

0

High-throughput

0.458

High

283020

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

283030

PTMS
Parathymosin

1

0

High-throughput

0.458

High

283035

TKT
Transketolase

1

0

High-throughput

0.458

High

283053

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

283055

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

283059

RS14
Small ribosomal subunit protein uS11

1

0

High-throughput

0.458

High

283073

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

283090

NBR1
Next to BRCA1 gene 1 protein

1

0

Small-scale

0.458

High

283104

MIDN
Midnolin

1

0

High-throughput

0.458

High

283107

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

283136

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

283140

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.458

High

283010

JUN
Transcription factor Jun

1

8

High-throughput

0.445

High

283024

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.445

High

282998

RHBT1
Rho-related BTB domain-containing protein 1

1

11

High-throughput

0.437

High

283003

AGR2
Anterior gradient protein 2 homolog

1

3

High-throughput

0.437

High

283110

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.437

High

283139

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

283142

DYH6
Dynein axonemal heavy chain 6

1

3

High-throughput

0.437

High

283144

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

283150

DYH2
Dynein axonemal heavy chain 2

1

3

High-throughput

0.437

High

283155

HECD1
E3 ubiquitin-protein ligase HECTD1

1

8

High-throughput

0.437

High

283045

CEBPA
CCAAT/enhancer-binding protein alpha

1

10

High-throughput

0.408

High

283103

LETM2
LETM1 domain-containing protein LETM2, mitochondrial

1

1

High-throughput

0.407

High

283088

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

283117

S35G3
Solute carrier family 35 member G3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025