HitPredict

Interactor 1: G3V6T7 (G3V6T7)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 72)
Gene: Pdia4

Interactor 2: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 643 Rn			1 1383
+	Hs
		411285 PDIA4_HUMAN (1-643): 0: 566: 86.82		INSR_HUMAN (27-1383): 0: 1527: 95.43
+	Hs
		435520 PDIA4_HUMAN (1-643): 0: 566: 86.82		IGF1R_HUMAN (13-1381): 0: 1302: 55.77
+	Hs
		411271 PDIA1_HUMAN (38-502): 8.13e-51: 185: 19.32		INSR_HUMAN (27-1383): 0: 1527: 95.43
+	Hs
		411391 PDIA6_HUMAN (519-631): 6.18e-27: 116: 28.32		INSR_HUMAN (27-1383): 0: 1527: 95.43
+	Hs
		423108 PDIA1_HUMAN (38-502): 8.13e-51: 185: 19.32		IGF1R_HUMAN (13-1381): 0: 1302: 55.77
+	Hs
		531732 PDIA4_HUMAN (1-643): 0: 566: 86.82		EPHB2_HUMAN (662-1317): 0: 577: 23.01
+	Hs
		531731 PDIA4_HUMAN (1-643): 0: 566: 86.82		EPHA8_HUMAN (663-1323): 1.14e-174: 548: 22.59
+	Hs
		445818 PDIA4_HUMAN (1-643): 0: 566: 86.82		ROS1_HUMAN (1020-1292): 1.06e-71: 267: 49.46
+	Hs
		532019 PDIA4_HUMAN (1-643): 0: 566: 86.82		ALK_HUMAN (997-1340): 6.12e-71: 264: 41.57
+	Hs
		531733 PDIA4_HUMAN (1-643): 0: 566: 86.82		LTK_HUMAN (1014-1292): 4.56e-70: 255: 43.82
+	Hs
		384191 PDIA4_HUMAN (1-643): 0: 566: 86.82		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		531813 PDIA4_HUMAN (1-643): 0: 566: 86.82		MERTK_HUMAN (810-1302): 3.9e-61: 230: 31.54
+	Hs
		531844 PDIA4_HUMAN (1-643): 0: 566: 86.82		NTRK3_HUMAN (997-1291): 5.26e-62: 230: 38.80
+	Hs
		531718 PDIA4_HUMAN (1-643): 0: 566: 86.82		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70
+	Hs
		383571 PDIA4_HUMAN (1-643): 0: 566: 86.82		ERBB2_HUMAN (32-342): 4.75e-18: 92.8: 19.83
+	Hs
		384104 PDIA1_HUMAN (38-502): 8.13e-51: 185: 19.32		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		384339 PDIA3_HUMAN (36-516): 2.32e-41: 159: 16.60		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		384875 PDIA6_HUMAN (519-631): 6.18e-27: 116: 28.32		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		337778 PDIA1_HUMAN (38-502): 8.13e-51: 185: 19.32		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		337993 PDIA3_HUMAN (36-516): 2.32e-41: 159: 16.60		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50