HitPredict

Interactor 1: REST (Q13127)
RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor)
Gene: REST

Interactor 2: RCOR1 (Q9UKL0)
REST corepressor 1 (Protein CoREST)
Gene: RCOR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.697

The method score is based on:

Property Details
Experiments 25197063, 10449787, 15897453, 17939992
Identification Methods affinity chromatography technology, two hybrid, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0010629 - negative regulation of gene expression
GO:0017053 - transcription repressor complex
and 1 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1097
Hs

1 485
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024