HitPredict

Interactor 1: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Interactor 2: IKKE (Q14164)
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)
Gene: IKBKE

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19820708
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016605 - PML body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 446 Hs			1 716
+	Hs
		1025586 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		TBK1_HUMAN (1-714): 4.2e-162: 486: 48.13
+	Hs
		1050233 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		IKKE_HUMAN (1-716): 1.32e-170: 508: 100.00
+	Hs
		1201936 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		TBK1_HUMAN (1-714): 4.2e-162: 486: 48.13
+	Hs
		158459 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		IKKB_HUMAN (9-701): 6.33e-128: 399: 18.97
+	Hs
		254480 ROCK2_HUMAN (113-339): 3.1e-10: 64.8: 17.02		IKKE_HUMAN (1-716): 1.32e-170: 508: 100.00
+	Hs
		1150633 MRCKG_HUMAN (193-428): 1.22e-12: 72.4: 13.53		TBK1_HUMAN (1-714): 4.2e-162: 486: 48.13
+	Hs
		158500 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		IKKB_HUMAN (9-701): 6.33e-128: 399: 18.97
+	Hs
		1201957 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		MRCKB_HUMAN (7-705): 4e-115: 382: 17.25
+	Hs
		167576 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		IKKA_HUMAN (9-700): 5.05e-116: 367: 18.31
+	Mm
		1112810 TAXB1_MOUSE (13-439): 3.84e-36: 143: 21.23		IKKA_MOUSE (9-700): 5.3e-115: 365: 18.72
+	Hs
		647929 DLG5_HUMAN (77-439): 7.24e-18: 88.6: 10.03		MARK3_HUMAN (9-654): 6.73e-126: 393: 15.46
+	Hs
		1137917 MRCKA_HUMAN (213-416): 6.71e-11: 66.7: 10.28		MRCKB_HUMAN (7-705): 4e-115: 382: 17.25
+	Hs
		1268126 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		MRCKB_HUMAN (7-705): 4e-115: 382: 17.25
+	Rn
		222476 MRCKA_RAT (81-439): 8.89e-16: 82.1: 10.80		MRCKB_RAT (7-705): 9.57e-107: 359: 16.69
+	Hs
		167488 MYH11_HUMAN (85-439): 1.1e-09: 62.8: 8.29		IKKA_HUMAN (9-700): 5.05e-116: 367: 18.31
+	Rn
		1186812 MRCKB_RAT (123-433): 1.73e-11: 68.6: 14.62		MRCKB_RAT (7-705): 9.57e-107: 359: 16.69
+	Hs
		1071723 MRCKB_HUMAN (99-376): 1.32e-09: 62.8: 9.94		KS6A2_HUMAN (6-290): 2.47e-89: 297: 21.95
+	Hs
		254459 ROCK2_HUMAN (113-339): 3.1e-10: 64.8: 17.02		KS6A3_HUMAN (6-294): 2.42e-88: 294: 22.34
+	Hs
		1268074 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		MARK4_HUMAN (9-262): 3.68e-86: 289: 28.21
+	Hs
		262262 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		ULK1_HUMAN (2-221): 1.05e-23: 109: 31.72