HitPredict

Interactor 1: CDK6 (Q00534)
Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)
Gene: CDK6

Interactor 2: WDR33 (Q9C0J8)
pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein of 146 kDa)
Gene: WDR33

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23602568
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 1336
+	Hs
		549232 CDK4_HUMAN (9-304): 6.58e-126: 363: 70.23		WDR33_HUMAN (1-1324): 0: 582: 96.35
+	Hs
		1025402 CDK6_HUMAN (1-326): 1.76e-146: 417: 100.00		FBXW7_HUMAN (229-428): 7.65e-42: 167: 21.89
+	Hs
		667968 CDK2_HUMAN (10-311): 3.29e-147: 417: 47.39		FBXW7_HUMAN (229-428): 7.65e-42: 167: 21.89
+	Hs
		667738 CDK2_HUMAN (10-311): 3.29e-147: 417: 47.39		GBB2_HUMAN (218-479): 4.72e-41: 156: 20.97
+	Hs
		443466 CDK1_HUMAN (10-305): 7.44e-130: 373: 45.18		FBXW7_HUMAN (229-428): 7.65e-42: 167: 21.89
+	Hs
		549211 CDK4_HUMAN (9-304): 6.58e-126: 363: 70.23		FBXW7_HUMAN (229-428): 7.65e-42: 167: 21.89
+	Hs
		667616 CDK2_HUMAN (10-311): 3.29e-147: 417: 47.39		LIS1_HUMAN (324-520): 8.27e-26: 113: 13.71
+	Hs
		443249 CDK1_HUMAN (10-305): 7.44e-130: 373: 45.18		LIS1_HUMAN (324-520): 8.27e-26: 113: 13.71