HitPredict

Interactor 1: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Interactor 2: MLP3C (Q9BXW4)
Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma)
Gene: MAP1LC3C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.751

Property	Details
Experiments	26451915, 32296183, 33723372, 25771791, 30679426, 23022382, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, pull down, x-ray crystallography, anti tag coimmunoprecipitation, nuclear magnetic resonance, fluorescence polarization spectroscopy, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000421 - autophagosome membrane GO:0005776 - autophagosome GO:0005829 - cytosol GO:0031410 - cytoplasmic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 446 Hs			1 147
+	Hs
		306150 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		GBRAP_HUMAN (13-127): 3.44e-54: 168: 38.26
+	Hs
		891120 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98
+	Hs
		1025553 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17
+	Hs
		1025548 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55
+	Hs
		1025551 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47
+	Hs
		1201898 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		MLP3C_HUMAN (1-147): 4.64e-72: 214: 100.00
+	Hs
		306222 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		GBRAP_HUMAN (13-127): 3.44e-54: 168: 38.26
+	Hs
		891207 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98
+	Hs
		1201902 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55
+	Hs
		1201905 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47
+	Hs
		1315808 CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07		MLP3C_HUMAN (1-147): 4.64e-72: 214: 100.00
+	Hs
		944705 MAP1A_HUMAN (159-425): 1.97e-12: 71.7: 12.64		MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17
+	Hs
		944703 MAP1A_HUMAN (159-425): 1.97e-12: 71.7: 12.64		MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55
+	Hs
		306342 CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07		GBRAP_HUMAN (13-127): 3.44e-54: 168: 38.26
+	Hs
		891347 CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07		GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98
+	Hs
		1051455 DCTN1_HUMAN (104-339): 7.78e-10: 63.2: 10.83		MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55
+	Hs
		1330650 CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07		MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17
+	Hs
		1326188 CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07		MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55
+	Hs
		725011 MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47
+	Hs
		1328053 CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47