Protein: CDK15
Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)

Gene: CDK15
Organism: Homo sapiens
Interactions: 116
UniProt ID: Q96Q40

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1106047

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

5

9

High-throughput

0.927

High

461834

HS90A
Heat shock protein HSP 90-alpha

5

20

High-throughput

0.922

High

1057647

CDK18
Cyclin-dependent kinase 18

3

15

High-throughput

0.847

High

1400518

CALL5
Calmodulin-like protein 5

2

11

High-throughput

0.811

High

468706

HS90B
Heat shock protein HSP 90-beta

2

20

High-throughput

0.776

High

1158483

CDC37
Hsp90 co-chaperone Cdc37

2

6

High-throughput

0.754

High

945074

RAB25
Ras-related protein Rab-25

2

2

High-throughput

0.726

High

1219535

ANR22
Ankyrin repeat domain-containing protein 22

2

1

High-throughput

0.726

High

1202002

H90B4
Putative heat shock protein HSP 90-beta 4

2

20

High-throughput

0.712

High

1202026

H90B3
Putative heat shock protein HSP 90-beta-3

2

20

High-throughput

0.712

High

1202064

HS905
Putative heat shock protein HSP 90-alpha A5

2

20

High-throughput

0.712

High

322115

CDK14
Cyclin-dependent kinase 14

1

18

High-throughput

0.691

High

692785

CALL3
Calmodulin-like protein 3

1

10

High-throughput

0.691

High

897947

CDK9
Cyclin-dependent kinase 9

1

18

High-throughput

0.691

High

667996

CDK2
Cyclin-dependent kinase 2

1

16

High-throughput

0.665

High

126250

ST2B1
Sulfotransferase 2B1

2

1

High-throughput

0.628

High

227127

SYNC
Asparagine--tRNA ligase, cytoplasmic

2

2

High-throughput

0.628

High

238673

AK1BA
Aldo-keto reductase family 1 member B10

2

1

High-throughput

0.628

High

248760

PEPL
Periplakin

2

17

High-throughput

0.628

High

277784

H2AY
Core histone macro-H2A.1

2

5

High-throughput

0.628

High

289276

SPB7
Serpin B7

2

7

High-throughput

0.628

High

369494

AACT
Alpha-1-antichymotrypsin

2

6

High-throughput

0.628

High

457904

INVO
Involucrin

2

5

High-throughput

0.628

High

587775

DESP
Desmoplakin

2

18

High-throughput

0.628

High

615228

IL1RA
Interleukin-1 receptor antagonist protein

2

2

High-throughput

0.628

High

652393

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

1

High-throughput

0.628

High

711733

RABP2
Cellular retinoic acid-binding protein 2

2

4

High-throughput

0.628

High

713434

SPB3
Serpin B3

2

7

High-throughput

0.628

High

724621

S10A7
Protein S100-A7

2

13

High-throughput

0.628

High

787694

SPB5
Serpin B5

2

8

High-throughput

0.628

High

818760

CAPG
Macrophage-capping protein

2

3

High-throughput

0.628

High

827897

STAT3
Signal transducer and activator of transcription 3

2

1

High-throughput

0.628

High

874847

SPB4
Serpin B4

2

7

High-throughput

0.628

High

895463

SPB8
Serpin B8

2

7

High-throughput

0.628

High

945842

EPIPL
Epiplakin

2

9

High-throughput

0.628

High

1061280

RHG01
Rho GTPase-activating protein 1

2

1

High-throughput

0.628

High

1125194

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

2

6

High-throughput

0.628

High

1187260

PA24E
Cytosolic phospholipase A2 epsilon

2

4

High-throughput

0.628

High

1256977

FBX50
F-box only protein 50

2

1

High-throughput

0.628

High

1286348

S1A7A
Protein S100-A7A

2

13

High-throughput

0.628

High

1292586

FCSD1
F-BAR and double SH3 domains protein 1

2

2

High-throughput

0.628

High

1325561

RDHE2
Epidermal retinol dehydrogenase 2

2

2

High-throughput

0.628

High

1352125

ES8L1
Epidermal growth factor receptor kinase substrate 8-like protein 1

2

13

High-throughput

0.628

High

1365172

NDRG1
Protein NDRG1

2

1

High-throughput

0.628

High

1368998

EVPL
Envoplakin

2

19

High-throughput

0.628

High

1400516

RNAS7
Ribonuclease 7

2

3

High-throughput

0.628

High

1400517

IL36G
Interleukin-36 gamma

2

2

High-throughput

0.628

High

1400520

I36RA
Interleukin-36 receptor antagonist protein

2

2

High-throughput

0.628

High

1400524

PSME2
Proteasome activator complex subunit 2

2

1

High-throughput

0.628

High

1400526

NDRG2
Protein NDRG2

2

1

High-throughput

0.628

High

1400528

PKP3
Plakophilin-3

2

9

High-throughput

0.628

High

1400522

AFF4
AF4/FMR2 family member 4

1

6

High-throughput

0.618

High

1106293

ROCK1
Rho-associated protein kinase 1

1

8

High-throughput

0.618

High

1194300

LARP7
La-related protein 7

1

17

High-throughput

0.618

High

1270503

MARK2
Serine/threonine-protein kinase MARK2

1

1

High-throughput

0.618

High

1399696

RBM14
RNA-binding protein 14

1

9

High-throughput

0.618

High

388002

FIBG
Fibrinogen gamma chain

2

0

High-throughput

0.602

High

391073

TRFL
Lactotransferrin

2

0

High-throughput

0.602

High

483953

HMOX1
Heme oxygenase 1

2

0

High-throughput

0.602

High

582610

PPAP
Prostatic acid phosphatase

2

0

High-throughput

0.602

High

627151

TYPH
Thymidine phosphorylase

2

0

High-throughput

0.602

High

839612

HUTH
Histidine ammonia-lyase

2

0

High-throughput

0.602

High

868100

AL1A3
Retinaldehyde dehydrogenase 3

2

0

High-throughput

0.602

High

1031123

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

2

0

High-throughput

0.602

High

1120594

IL18
Interleukin-18

2

0

High-throughput

0.602

High

1253043

ACP7
Acid phosphatase type 7

2

0

High-throughput

0.602

High

1400513

NIBA2
Protein Niban 2

2

0

High-throughput

0.602

High

1400514

TREX2
Three prime repair exonuclease 2

2

0

High-throughput

0.602

High

1400525

ASC
Apoptosis-associated speck-like protein containing a CARD

2

0

High-throughput

0.602

High

1217677

AXA81
Annexin A8-like protein 1

2

3

High-throughput

0.601

High

369908

CO3
Complement C3

2

2

High-throughput

0.574

High

721521

ILEU
Leukocyte elastase inhibitor

2

7

High-throughput

0.574

High

892132

KLK7
Kallikrein-7

2

1

High-throughput

0.574

High

1120951

TRI29
Tripartite motif-containing protein 29

2

9

High-throughput

0.574

High

1358555

POF1B
Protein POF1B

2

1

High-throughput

0.574

High

1400529

CRBG1
Beta/gamma crystallin domain-containing protein 1

2

3

High-throughput

0.574

High

1400530

SQOR
Sulfide:quinone oxidoreductase, mitochondrial

2

1

High-throughput

0.574

High

1216238

H37
Histone H3-7

2

3

High-throughput

0.552

High

577864

PLAK
Junction plakoglobin

1

10

High-throughput

0.536

High

609779

LEG3
Galectin-3

1

2

High-throughput

0.536

High

717227

KCY
UMP-CMP kinase

1

3

High-throughput

0.536

High

862946

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

7

High-throughput

0.536

High

868759

LEG7
Galectin-7

1

2

High-throughput

0.536

High

1054634

PSME1
Proteasome activator complex subunit 1

1

1

High-throughput

0.536

High

1062286

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.536

High

1214757

ATD3B
ATPase family AAA domain-containing protein 3B

1

8

High-throughput

0.536

High

1400515

SDCB2
Syntenin-2

1

4

High-throughput

0.536

High

1400521

ZO2
Tight junction protein 2

1

5

High-throughput

0.536

High

75710

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

2

2

High-throughput

0.533

High

183361

ZN185
Zinc finger protein 185

1

0

High-throughput

0.513

High

636180

ENDOU
Uridylate-specific endoribonuclease

1

0

High-throughput

0.513

High

728991

ABC3A
DNA dC->dU-editing enzyme APOBEC-3A

1

0

High-throughput

0.513

High

870656

MAOX
NADP-dependent malic enzyme

1

0

High-throughput

0.513

High

1251134

PNCB
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.513

High

1400512

GSDMA
Gasdermin-A

1

0

High-throughput

0.513

High

69534

A2ML1
Alpha-2-macroglobulin-like protein 1

2

2

High-throughput

0.504

High

379130

IGKC
Immunoglobulin kappa constant

2

4

High-throughput

0.504

High

379297

IGHG1
Immunoglobulin heavy constant gamma 1

2

6

High-throughput

0.504

High

379386

IGHG2
Immunoglobulin heavy constant gamma 2

2

5

High-throughput

0.504

High

1400519

DNM3B
DNA

1

0

High-throughput

0.493

High

210775

KLK10
Kallikrein-10

1

1

High-throughput

0.489

High

296734

TUSC2
Tumor suppressor candidate 2

1

1

High-throughput

0.489

High

325057

HEXI1
Protein HEXIM1

1

8

High-throughput

0.479

High

899537

TCPD
T-complex protein 1 subunit delta

1

16

High-throughput

0.479

High

1007213

TCPB
T-complex protein 1 subunit beta

1

19

High-throughput

0.479

High

1103647

PHLP
Phosducin-like protein

1

2

High-throughput

0.479

High

1334797

SERB1
SERPINE1 mRNA-binding protein 1

1

8

High-throughput

0.479

High

1363676

TCPW
T-complex protein 1 subunit zeta-2

1

19

High-throughput

0.479

High

1400527

NOP58
Nucleolar protein 58

1

0

High-throughput

0.458

High

252946

UD19
UDP-glucuronosyltransferase 1A9

2

0

High-throughput

0.328

High

389675

A1AG1
Alpha-1-acid glycoprotein 1

2

0

High-throughput

0.328

High

1248725

SBSN
Suprabasin

2

0

High-throughput

0.328

High

1359105

TMM40
Transmembrane protein 40

2

0

High-throughput

0.328

High

1400523

CBPA4
Carboxypeptidase A4

2

0

High-throughput

0.328

High

137790

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.279

Low

1065890

MB214
Protein mab-21-like 4

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025