Interactor 1: PAK1 (Q13153)
Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)
Gene: PAK1
Interactor 2: ARHG6 (Q15052)
Rho guanine nucleotide exchange factor 6 (Alpha-Pix) (COOL-2) (PAK-interacting exchange factor alpha) (Rac/Cdc42 guanine nucleotide exchange factor 6)
Gene: ARHGEF6
Species: Homo sapiens
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.973 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 32203420, 33961781, 21900206, 31980649, 35271311, 23455922, unassigned2173, unassigned2213 |
| Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~Pkinase |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005911 - cell-cell junction GO:0006915 - apoptotic process GO:0030027 - lamellipodium |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
