HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: ZN644 (Q9H582)
Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2)
Gene: ZNF644

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	24981860, 27705803, 34079125, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 1327
+	Hs
		64140 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN729_HUMAN (10-757): 0: 596: 14.86
+	Hs
		64135 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		ZN729_HUMAN (10-757): 0: 596: 14.86
+	Hs
		67424 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN850_HUMAN (564-1317): 1.81e-169: 536: 11.18
+	Hs
		728565 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF93_HUMAN (525-1063): 4.43e-90: 307: 13.52
+	Hs
		1027102 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN227_HUMAN (23-346): 4.62e-74: 265: 8.76
+	Hs
		1027294 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN226_HUMAN (888-1317): 3.65e-66: 242: 10.63
+	Hs
		563302 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF16_HUMAN (696-1283): 8.54e-62: 227: 10.14
+	Hs
		1027128 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN565_HUMAN (345-580): 2.37e-56: 207: 17.16
+	Hs
		64158 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		ZN726_HUMAN (274-519): 1.4e-60: 221: 18.81
+	Hs
		1027212 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN382_HUMAN (346-521): 3.23e-35: 144: 19.23
+	Hs
		1027143 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN420_HUMAN (1126-1318): 3.62e-32: 137: 10.88
+	Hs
		983755 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF91_HUMAN (23-160): 2.36e-31: 135: 10.42
+	Hs
		1027123 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN283_HUMAN (456-627): 2.69e-31: 134: 19.55
+	Hs
		1027217 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN184_HUMAN (1081-1310): 2.1e-31: 134: 10.87
+	Hs
		1027274 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN287_HUMAN (297-438): 4.57e-25: 114: 16.27
+	Hs
		321765 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		WIZ_HUMAN (958-1083): 6.06e-23: 108: 41.27
+	Mm
		291345 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		WIZ_MOUSE (958-1083): 2.97e-22: 106: 41.27
+	Hs
		67855 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		ZN724_HUMAN (411-693): 1.63e-34: 143: 16.67
+	Hs
		1027309 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN629_HUMAN (1223-1325): 2.53e-17: 90.1: 9.71
+	Hs
		321723 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		WIZ_HUMAN (958-1083): 6.06e-23: 108: 41.27