HitPredict

Interactor 1: DNJC3 (Q13217)
DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)
Gene: DNAJC3

Interactor 2: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31932471
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 552
+	Hs
		636483 DNJB2_HUMAN (394-501): 1.3e-34: 134: 41.88		SMAD4_HUMAN (1-552): 0: 696: 100.00
+	Hs
		171439 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		SMAD9_HUMAN (20-546): 0: 535: 34.28
+	Hs
		1078640 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		SMAD2_HUMAN (19-549): 1.81e-166: 482: 28.65
+	Hs
		279288 DNJB5_HUMAN (392-495): 4.16e-36: 139: 39.13		SMAD3_HUMAN (19-549): 1.96e-176: 506: 31.22
+	Hs
		279301 DNJB5_HUMAN (392-495): 4.16e-36: 139: 39.13		SMAD2_HUMAN (19-549): 1.81e-166: 482: 28.65
+	Hs
		672809 CDC27_HUMAN (130-487): 4.57e-18: 89.8: 11.83		SMAD3_HUMAN (19-549): 1.96e-176: 506: 31.22
+	Hs
		672840 CDC27_HUMAN (130-487): 4.57e-18: 89.8: 11.83		SMAD2_HUMAN (19-549): 1.81e-166: 482: 28.65
+	Hs
		174919 OGT1_HUMAN (13-134): 3.34e-16: 84: 18.03		SMAD2_HUMAN (19-549): 1.81e-166: 482: 28.65