HitPredict

Interactor 1: SRSF5 (Q13243)
Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5)
Gene: SRSF5

Interactor 2: SF3A2 (Q15428)
Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62)
Gene: SF3A2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17332742
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~zf-met
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0006397 - mRNA processing GO:0016607 - nuclear speck
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 464
+	Hs
		992787 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Hs
		993724 SRSF4_HUMAN (5-265): 3.78e-51: 176: 53.64		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Hs
		1028554 SRSF9_HUMAN (2-211): 1.47e-52: 172: 33.02		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Hs
		1028927 SRSF6_HUMAN (5-184): 1.35e-48: 165: 61.96		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Hs
		951978 SRSF3_HUMAN (4-78): 1.85e-11: 62.8: 47.56		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Hs
		1028819 SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00		ZN768_HUMAN (277-449): 2.74e-22: 101: 27.32
+	Hs
		993831 SRSF4_HUMAN (5-265): 3.78e-51: 176: 53.64		ZN768_HUMAN (277-449): 2.74e-22: 101: 27.32
+	Hs
		1029092 SRSF6_HUMAN (5-184): 1.35e-48: 165: 61.96		ZN768_HUMAN (277-449): 2.74e-22: 101: 27.32
+	Hs
		516595 PABP1_HUMAN (98-189): 1.16e-15: 78.6: 18.56		KMT2C_HUMAN (73-462): 1.38e-16: 85.1: 12.59
+	Hs
		1031405 PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98		TITIN_HUMAN (290-460): 7.67e-09: 60.4: 18.50
+	Hs
		516609 PABP1_HUMAN (98-189): 1.16e-15: 78.6: 18.56		TITIN_HUMAN (290-460): 7.67e-09: 60.4: 18.50