Protein: SYFM
Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS)

Gene: SYFM, FARS2
Organism: Homo sapiens
Interactions: 133
UniProt ID: O95363

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0004826 - phenylalanine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

307237

RCBT2
RCC1 and BTB domain-containing protein 2

3

1

High-throughput

0.675

High

311983

TRIM1
Probable E3 ubiquitin-protein ligase MID2

3

5

High-throughput

0.675

High

311985

IKZF3
Zinc finger protein Aiolos

3

1

High-throughput

0.675

High

311919

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

4

0

High-throughput

0.668

High

311984

DP13A
DCC-interacting protein 13-alpha

4

0

High-throughput

0.668

High

311982

ZRAN1
Ubiquitin thioesterase ZRANB1

3

1

High-throughput

0.653

High

311882

ROA1
Heterogeneous nuclear ribonucleoprotein A1

3

0

High-throughput

0.638

High

311923

GAMT
Guanidinoacetate N-methyltransferase

3

0

High-throughput

0.634

High

311903

KR107
Keratin-associated protein 10-7

3

5

High-throughput

0.616

High

311905

KR109
Keratin-associated protein 10-9

3

5

High-throughput

0.616

High

311934

K1C40
Keratin, type I cytoskeletal 40

3

4

High-throughput

0.616

High

311910

YBOX1
Y-box-binding protein 1

2

2

Small-scale

0.611

High

311921

CUL3
Cullin-3

2

2

High-throughput

0.611

High

311913

H11
Histone H1.1

3

5

High-throughput

0.609

High

311917

TRAF2
TNF receptor-associated factor 2

2

2

High-throughput

0.606

High

311920

GRB10
Growth factor receptor-bound protein 10

2

2

High-throughput

0.606

High

311928

TRIP6
Thyroid receptor-interacting protein 6

2

1

High-throughput

0.606

High

311950

KCD17
BTB/POZ domain-containing protein KCTD17

2

1

High-throughput

0.606

High

311951

ZN655
Zinc finger protein 655

2

1

High-throughput

0.606

High

311967

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

2

2

High-throughput

0.606

High

311961

RM38
Large ribosomal subunit protein mL38

2

0

High-throughput

0.602

High

68012

HIG1C
HIG1 domain family member 1C

2

0

High-throughput

0.580

High

311875

BAG4
BAG family molecular chaperone regulator 4

2

0

High-throughput

0.580

High

311931

BEX5
Protein BEX5

2

0

High-throughput

0.580

High

311966

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.580

High

311968

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

311885

H14
Histone H1.4

2

5

High-throughput

0.574

High

311893

H1T
Histone H1t

2

5

High-throughput

0.574

High

311935

HMBX1
Homeobox-containing protein 1

1

2

High-throughput

0.573

High

311974

TRI54
Tripartite motif-containing protein 54

1

5

High-throughput

0.573

High

50887

FSD2
Fibronectin type III and SPRY domain-containing protein 2

2

5

High-throughput

0.553

High

230677

ZN500
Zinc finger protein 500

2

2

High-throughput

0.553

High

280501

KRT34
Keratin, type I cuticular Ha4

2

4

High-throughput

0.553

High

311904

KR108
Keratin-associated protein 10-8

2

5

High-throughput

0.553

High

311914

KRA11
Keratin-associated protein 1-1

2

5

High-throughput

0.553

High

311946

ZN438
Zinc finger protein 438

2

1

High-throughput

0.553

High

311955

IKBD
NF-kappa-B inhibitor delta

2

3

High-throughput

0.553

High

311964

AJUBA
LIM domain-containing protein ajuba

2

1

High-throughput

0.553

High

311975

BACH2
Transcription regulator protein BACH2

2

2

High-throughput

0.553

High

311887

TRI27
Zinc finger protein RFP

1

0

High-throughput

0.549

High

311945

NT2NA
Notch homolog 2 N-terminal-like protein A

1

0

High-throughput

0.549

High

311927

OASL
2'-5'-oligoadenylate synthase-like protein

1

3

High-throughput

0.536

High

311979

LN28A
Protein lin-28 homolog A

1

2

High-throughput

0.536

High

311990

YBOX2
Y-box-binding protein 2

1

2

High-throughput

0.536

High

311918

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

1

1

High-throughput

0.523

High

311926

K1H1
Keratin, type I cuticular Ha1

1

4

High-throughput

0.523

High

311897

TCPZ
T-complex protein 1 subunit zeta

1

2

High-throughput

0.515

High

311942

UBP45
Ubiquitin carboxyl-terminal hydrolase 45

1

3

High-throughput

0.515

High

311989

G3BP2
Ras GTPase-activating protein-binding protein 2

1

2

High-throughput

0.515

High

311981

RIM3A
RIMS-binding protein 3A

1

1

High-throughput

0.515

High

311877

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

0

High-throughput

0.513

High

311888

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

311892

ANFB
Natriuretic peptides B

1

0

High-throughput

0.513

High

311894

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.513

High

311896

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.513

High

311899

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.513

High

311900

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

0

High-throughput

0.513

High

311907

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

311908

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.513

High

311909

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.513

High

311912

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

311922

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.513

High

311936

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

0

High-throughput

0.513

High

311943

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.513

High

311947

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

311959

FGF13
Fibroblast growth factor 13

1

0

High-throughput

0.513

High

311963

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

311976

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.513

High

311986

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

171717

WDR46
WD repeat-containing protein 46

1

1

High-throughput

0.489

High

311884

GLI4
Zinc finger protein GLI4

1

2

High-throughput

0.489

High

311889

H15
Histone H1.5

1

5

High-throughput

0.489

High

311890

H13
Histone H1.3

1

5

High-throughput

0.489

High

311891

H12
Histone H1.2

1

5

High-throughput

0.489

High

311929

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

1

High-throughput

0.489

High

311954

NEDD1
Protein NEDD1

1

1

High-throughput

0.489

High

311987

ZN490
Zinc finger protein 490

1

1

High-throughput

0.489

High

63547

RIM3C
RIMS-binding protein 3C

1

1

High-throughput

0.481

High

226142

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

311879

ISG15
Ubiquitin-like protein ISG15

1

4

High-throughput

0.479

High

311895

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

311941

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

311978

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

49545

A1A4E9
Keratin 13

1

3

High-throughput

0.470

High

311902

KR105
Keratin-associated protein 10-5

1

5

High-throughput

0.470

High

311906

RL26
Large ribosomal subunit protein uL24

1

0

High-throughput

0.458

High

311992

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.458

High

311886

K1C13
Keratin, type I cytoskeletal 13

1

3

High-throughput

0.439

High

311901

KR103
Keratin-associated protein 10-3

1

5

High-throughput

0.439

High

311932

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

0

High-throughput

0.438

High

311938

ATRAP
Type-1 angiotensin II receptor-associated protein

3

0

High-throughput

0.352

High

311962

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

3

0

High-throughput

0.352

High

311956

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

2

0

High-throughput

0.328

High

311952

BANP
Protein BANP

2

0

High-throughput

0.320

High

66932

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

208313

SPY1
Protein sprouty homolog 1

2

0

High-throughput

0.316

High

303871

YIF1A
Protein YIF1A

2

0

High-throughput

0.316

High

311880

TPM2
Tropomyosin beta chain

2

0

High-throughput

0.316

High

311881

SYPH
Synaptophysin

2

0

High-throughput

0.316

High

311915

AP1B1
AP-1 complex subunit beta-1

2

0

High-throughput

0.316

High

311924

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

311930

CC152
Coiled-coil domain-containing protein 152

2

0

High-throughput

0.316

High

311933

FHL5
Four and a half LIM domains protein 5

2

0

High-throughput

0.316

High

311937

MORN3
MORN repeat-containing protein 3

2

0

High-throughput

0.316

High

311940

DG2L6
Diacylglycerol O-acyltransferase 2-like protein 6

2

0

High-throughput

0.316

High

311953

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.316

High

311957

ZN526
Zinc finger protein 526

2

0

High-throughput

0.316

High

311958

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

0

High-throughput

0.316

High

311960

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

0

High-throughput

0.316

High

311969

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

2

0

High-throughput

0.316

High

311972

CDCA4
Cell division cycle-associated protein 4

2

0

High-throughput

0.316

High

311973

KRA33
Keratin-associated protein 3-3

2

0

High-throughput

0.316

High

311977

KCNF1
Potassium voltage-gated channel subfamily F member 1

2

0

High-throughput

0.316

High

311980

MA1C1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC

2

0

High-throughput

0.316

High

311988

ISY1
Pre-mRNA-splicing factor ISY1 homolog

2

0

High-throughput

0.316

High

311991

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

0

High-throughput

0.316

High

266291

TAD2A
Transcriptional adapter 2-alpha

1

0

High-throughput

0.299

High

269381

STX11
Syntaxin-11

1

0

High-throughput

0.299

High

311916

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.299

High

311939

ATL4
ADAMTS-like protein 4

1

0

High-throughput

0.299

High

272956

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.279

Low

311876

CBX6
Chromobox protein homolog 6

1

0

High-throughput

0.279

Low

311883

H2A1
Histone H2A type 1

1

0

High-throughput

0.279

Low

311898

STA5A
Signal transducer and activator of transcription 5A

1

0

High-throughput

0.279

Low

311911

PRR3
Proline-rich protein 3

1

0

High-throughput

0.279

Low

311925

RRS1
Ribosome biogenesis regulatory protein homolog

1

0

High-throughput

0.279

Low

311944

CHSTF
Carbohydrate sulfotransferase 15

1

0

High-throughput

0.279

Low

311965

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

311970

LLPH
Protein LLP homolog

1

0

High-throughput

0.279

Low

311971

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.279

Low

311948

HOMEZ
Homeobox and leucine zipper protein Homez

1

0

High-throughput

0.251

Low

311878

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.249

Low

311949

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024