HitPredict

Interactor 1: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Interactor 2: SFR19 (Q9H7N4)
Splicing factor, arginine/serine-rich 19 (SR-related C-terminal domain-associated factor 1) (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1)
Gene: SCAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 1312
+	Hs
		992936 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		SFR19_HUMAN (1-1295): 3.65e-102: 356: 100.00
+	Hs
		1314620 RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05		SFR19_HUMAN (1-1295): 3.65e-102: 356: 100.00
+	Hs
		993833 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		SFR19_HUMAN (1-1295): 3.65e-102: 356: 100.00
+	Hs
		1028822 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		SFR19_HUMAN (1-1295): 3.65e-102: 356: 100.00
+	Hs
		992900 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		SCAFB_HUMAN (53-1289): 2.43e-44: 178: 13.25
+	Hs
		1028784 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		SCAFB_HUMAN (53-1289): 2.43e-44: 178: 13.25
+	Hs
		1029053 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		SCAFB_HUMAN (53-1289): 2.43e-44: 178: 13.25
+	Hs
		992772 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		MDC1_HUMAN (32-1063): 5.74e-36: 151: 9.11
+	Hs
		1028547 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		MDC1_HUMAN (32-1063): 5.74e-36: 151: 9.11
+	Hs
		1028609 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		SHAN3_HUMAN (96-695): 1.19e-27: 124: 16.59
+	Hs
		992995 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		SRRM2_HUMAN (450-1311): 6.2e-14: 79.5: 12.17
+	Dm
		644444 SRR55_DROME (3-337): 3.03e-47: 165: 46.86		Q9VLS7_DROME (239-1295): 8.23e-16: 85.6: 8.69
+	Hs
		992756 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		PRP4K_HUMAN (514-804): 6.19e-11: 69.2: 20.82
+	Hs
		993872 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		SRRM2_HUMAN (450-1311): 6.2e-14: 79.5: 12.17
+	Hs
		1028876 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		SRRM2_HUMAN (450-1311): 6.2e-14: 79.5: 12.17
+	Hs
		993706 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		PRP4K_HUMAN (514-804): 6.19e-11: 69.2: 20.82
+	Hs
		1029050 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		MINT_HUMAN (2-1306): 5.68e-13: 76.4: 8.53
+	Hs
		1028642 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		PRP4K_HUMAN (514-804): 6.19e-11: 69.2: 20.82
+	Hs
		1037875 RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23		PRP4K_HUMAN (514-804): 6.19e-11: 69.2: 20.82
+	Hs
		1028893 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		PRP4K_HUMAN (514-804): 6.19e-11: 69.2: 20.82