Protein: SF3B3
Splicing factor 3B subunit 3

Gene: SF3B3
Organism: Drosophila melanogaster
Interactions: 59
UniProt ID: Q9W0M7

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005686 - U2 snRNP
GO:0030532 - small nuclear ribonucleoprotein complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1476229

SF3B5
Splicing factor 3B subunit 5

3

1

Small-scale

0.849

High

1485210

SF3B6
Splicing factor 3B subunit 6

2

9

High-throughput

0.737

High

1470613

TAF5L
Protein will decrease acetylation

1

12

Small-scale

0.713

High

356696

PLK4
Serine/threonine-protein kinase PLK4

1

6

High-throughput

0.656

High

875392

CDK5
Cyclin-dependent kinase 5 homolog

1

2

High-throughput

0.656

High

1265623

Q7K306
cyclin-dependent kinase

1

3

High-throughput

0.656

High

1303758

AKT1
RAC serine/threonine-protein kinase

1

2

High-throughput

0.656

High

1471348

Q9VD82
Cyclin-dependent kinase 20

1

4

High-throughput

0.656

High

847944

SNRPA
U1 small nuclear ribonucleoprotein A

1

4

Small-scale

0.618

High

1483504

Q9VPR5
Splicing factor 3B subunit 1

2

3

High-throughput

0.571

High

1489412

Q9W592
EG:BACN32G11.3 protein

2

1

High-throughput

0.571

High

1489411

SGF29
SAGA-associated factor 29kDa

1

1

Small-scale

0.552

High

304894

E2F2
Transcription factor E2F2

1

3

High-throughput

0.508

High

837190

MAD
Protein mothers against dpp

1

1

High-throughput

0.508

High

1378207

CYCG
Cyclin G

1

1

High-throughput

0.508

High

1489410

Q9W1J7
SKP1 component POZ domain-containing protein

1

1

High-throughput

0.508

High

895411

RUX
Cell cycle negative regulator roughex

1

0

High-throughput

0.486

High

304014

O76513
Cyclin-H

1

6

High-throughput

0.481

High

1216719

Q5U0V6
Cell division cycle 14, isoform B

1

7

High-throughput

0.481

High

1261223

Q7JNL9
Dacapo

1

1

High-throughput

0.481

High

1269927

Q7KUZ5
Cyclin D, isoform D

1

1

High-throughput

0.481

High

1379285

Q961D1
Cyclin-K

1

4

High-throughput

0.481

High

1439975

SIRT2
NAD-dependent protein deacetylase Sirt2

1

5

High-throughput

0.481

High

1489120

Q9VZP3
Cyclin J, isoform A

1

1

High-throughput

0.481

High

1302207

TAD2B
Transcriptional adapter 2b

1

3

Small-scale

0.479

High

1304478

TAD12
Transcriptional adapter 1-2

1

1

Small-scale

0.479

High

1474606

SPT3
SAGA complex subunit Spt3

1

2

Small-scale

0.479

High

1466846

Q9V9R6
No mechanoreceptor potential B, isoform C

1

4

High-throughput

0.464

High

1488080

SPT7
SAGA complex subunit Spt7

1

0

Small-scale

0.460

High

120019

M9PC25
SAGA factor-like TAF6, isoform B

1

0

Small-scale

0.458

High

1484085

ATX7
Ataxin-7

1

0

Small-scale

0.458

High

195987

O17144
Cyclin-H

1

6

High-throughput

0.457

High

1427810

Q9GTQ8
Cyclin D

1

1

High-throughput

0.457

High

1481304

Q9VLW7
Cell division cycle 14, isoform A

1

7

High-throughput

0.457

High

1266579

NCBP1
Nuclear cap-binding protein subunit 1

1

4

High-throughput

0.445

High

1476699

IF4A3
Eukaryotic initiation factor 4A-III

1

3

High-throughput

0.445

High

1478246

Q9VJ86
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.445

High

1479995

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

6

High-throughput

0.445

High

69227

A8JUS8
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

839958

PLU
DNA replication inhibitor plutonium

1

1

High-throughput

0.439

High

1488440

Q9VXR9
FI03680p

1

1

High-throughput

0.439

High

705032

EXU
Maternal protein exuperantia

1

0

High-throughput

0.426

High

1019377

P91668
Cyclin-dependent kinase inhibitor Dacapo

1

1

High-throughput

0.417

High

1285319

Q868J0
PLU

1

1

High-throughput

0.417

High

1344722

Q8SYZ4
NAD-dependent protein deacetylase

1

5

High-throughput

0.417

High

1379476

Q961V9
GH03273p

1

1

High-throughput

0.417

High

1489413

Q9W5G0
LD08762p

1

1

High-throughput

0.417

High

1468813

Q9VB04
Protein CASC3

1

1

High-throughput

0.407

High

1488804

RENT1
Regulator of nonsense transcripts 1 homolog

1

1

High-throughput

0.407

High

1480959

Q9VLP6
LD46912p

2

0

High-throughput

0.298

High

1481023

MPPE1
Metallophosphoesterase 1 homolog

1

0

High-throughput

0.265

Low

1482637

POLZ2
DNA polymerase zeta subunit 2

1

0

High-throughput

0.265

Low

1483568

CH60B
60 kDa heat shock protein homolog 1, mitochondrial

1

0

High-throughput

0.265

Low

1486255

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.265

Low

52977

A1Z7I1
Uncharacterized protein, isoform C

1

0

High-throughput

0.251

Low

615129

PTC
Protein patched

1

0

High-throughput

0.251

Low

1302754

Q8IGE8
RH36596p

1

0

High-throughput

0.238

Low

726514

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

1480331

Q9VL60
RE01590p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025