HitPredict

Interactor 1: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 783
+	Hs
		1314627 RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1028626 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		993846 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1028839 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1344201 S4R3G0_HUMAN (3-115): 5.16e-23: 94.2: 32.20		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		992907 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1271643 RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		1028788 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1308743 RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		571581 RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		1029059 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Mm
		857323 TIA1_MOUSE (2-335): 1.54e-33: 129: 15.46		DDX17_MOUSE (122-628): 3.34e-135: 417: 24.46
+	Mm
		857351 TIA1_MOUSE (2-335): 1.54e-33: 129: 15.46		Q8BTS0_MOUSE (92-620): 1.47e-135: 416: 24.81
+	Sc
		624156 NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94		DBP2_YEAST (77-561): 8.25e-130: 399: 25.46
+	Hs
		757583 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757593 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757584 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757594 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757595 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Sc
		416057 NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94		DED1_YEAST (196-541): 2.98e-56: 205: 37.98