HitPredict

Interactor 1: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Interactor 2: DDX41 (Q9UJV9)
Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) (DEAD box protein abstrakt homolog)
Gene: DDX41

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25920683
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 344 Hs			1 622
+	Hs
		992985 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		DDX41_HUMAN (1-622): 4.69e-171: 502: 100.00
+	Hs
		1028630 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		DDX41_HUMAN (1-622): 4.69e-171: 502: 100.00
+	Hs
		993864 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		DDX41_HUMAN (1-622): 4.69e-171: 502: 100.00
+	Hs
		1028866 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		DDX41_HUMAN (1-622): 4.69e-171: 502: 100.00
+	Hs
		1271643 RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05		DDX17_HUMAN (116-622): 2.31e-144: 437: 33.33
+	Hs
		571581 RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05		DDX5_HUMAN (88-617): 1.42e-145: 437: 30.80
+	Hs
		1347046 RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61		DDX41_HUMAN (1-622): 4.69e-171: 502: 100.00
+	Mm
		857351 TIA1_MOUSE (2-335): 1.54e-33: 129: 15.46		Q8BTS0_MOUSE (88-617): 2.65e-145: 436: 30.80
+	Mm
		857323 TIA1_MOUSE (2-335): 1.54e-33: 129: 15.46		DDX17_MOUSE (116-622): 1.78e-144: 435: 33.33
+	Hs
		952172 SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84		DDX41_HUMAN (1-622): 4.69e-171: 502: 100.00
+	Sc
		624156 NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94		DBP2_YEAST (71-563): 6.45e-141: 422: 35.14
+	Mm
		936480 TIAR_MOUSE (2-120): 5.05e-13: 71.5: 17.89		DDX5_MOUSE (88-617): 4.33e-146: 438: 30.80
+	Hs
		1271680 RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61		DDX17_HUMAN (116-622): 2.31e-144: 437: 33.33
+	Hs
		134018 PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88		DDX3X_HUMAN (19-592): 1.62e-139: 423: 29.70
+	Hs
		133858 PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79		DDX3X_HUMAN (19-592): 1.62e-139: 423: 29.70
+	Sc
		416057 NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94		DED1_YEAST (173-589): 1.72e-89: 291: 38.93
+	Sc
		376580 PABP_YEAST (99-194): 1.33e-11: 67.6: 19.80		DED1_YEAST (173-589): 1.72e-89: 291: 38.93