HitPredict

Interactor 1: PTK7 (Q13308)
Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7)
Gene: PTK7

Interactor 2: PPM1K (Q8N3J5)
Protein phosphatase Mn(2+)-dependent 1K (EC 3.1.3.16) (Branched-chain alpha-ketoacid dehydrogenase phosphatase) (BCKDH) (BDP) (EC 3.1.3.52) (PP2C domain-containing protein phosphatase 1K) (PP2C-like mitochondrial protein) (PP2C-type mitochondrial phosphoprotein phosphatase) (PTMP) (Protein phosphatase 2C family member) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) ([3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase, mitochondrial)
Gene: PPM1K

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	28065597
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1070 Hs			1 372
+	Hs
		728673 ALK_HUMAN (695-1067): 1.21e-52: 204: 32.90		PPM1A_HUMAN (72-362): 4.23e-103: 310: 27.94
+	Hs
		728604 PTK7_HUMAN (2-329): 4.66e-52: 201: 19.94		PPM1A_HUMAN (72-362): 4.23e-103: 310: 27.94
+	Hs
		273427 PTK7_HUMAN (2-329): 4.66e-52: 201: 19.94		PPM1B_HUMAN (72-362): 1.82e-98: 302: 27.19
+	Hs
		601473 FGFR2_HUMAN (297-603): 8.71e-43: 170: 18.52		PPM1A_HUMAN (72-362): 4.23e-103: 310: 27.94
+	Hs
		273355 FGFR1_HUMAN (2-231): 7.15e-34: 142: 12.41		PPM1B_HUMAN (72-362): 1.82e-98: 302: 27.19
+	Hs
		1031167 PTK7_HUMAN (2-329): 4.66e-52: 201: 19.94		ILKAP_HUMAN (114-347): 8.95e-27: 111: 32.06
+	Hs
		169202 MUSK_HUMAN (130-422): 5.54e-12: 72: 21.93		ILKAP_HUMAN (114-347): 8.95e-27: 111: 32.06