Protein: PEP12
Syntaxin PEP12 (Carboxypeptidase Y-deficient protein 12) (Vacuolar protein sorting-associated protein 6) (Vacuolar protein-targeting protein 13)

Gene: PEP12
Organism: Saccharomyces cerevisiae S288C
Interactions: 58
UniProt ID: P32854

Gene Ontology (top 5):
GO:0000011 - vacuole inheritance
GO:0000139 - Golgi membrane
GO:0000149 - SNARE binding
GO:0000329 - fungal-type vacuole membrane
GO:0005484 - SNAP receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

746147

VTI1
t-SNARE VTI1

5

20

Small-scale

0.924

High

746125

YKT6
Synaptobrevin homolog YKT6

4

20

Small-scale

0.899

High

635026

VPS33
Vacuolar protein sorting-associated protein 33

2

20

Small-scale

0.806

High

746133

VPS45
Vacuolar protein sorting-associated protein 45

2

20

Small-scale

0.754

High

724259

SNC1
Synaptobrevin homolog 1

1

20

Small-scale

0.665

High

746145

TLG1
t-SNARE affecting a late Golgi compartment protein 1

3

20

Small-scale

0.650

High

646222

SEC22
Protein transport protein SEC22

1

20

Small-scale

0.647

High

746123

SNC2
Synaptobrevin homolog 2

1

20

Small-scale

0.647

High

746131

GOSR1
Golgi SNAP receptor complex member 1

1

20

Small-scale

0.647

High

746154

NYV1
Vacuolar v-SNARE NYV1

1

20

Small-scale

0.647

High

392463

HSP82
ATP-dependent molecular chaperone HSP82

2

8

Small-scale

0.614

High

746153

GET3
ATPase GET3

1

2

Small-scale

0.604

High

746155

PRP46
Pre-mRNA-splicing factor PRP46

3

1

Small-scale

0.603

High

743445

SEC17
Alpha-soluble NSF attachment protein

1

20

High-throughput

0.590

High

746141

ENT3
Epsin-3

2

4

Small-scale

0.586

High

746136

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

High-throughput

0.586

High

746152

ATG9
Autophagy-related protein 9

2

4

High-throughput

0.584

High

725992

STX8
Syntaxin-8

2

0

Small-scale

0.576

High

745289

TMN1
Transmembrane 9 superfamily member 1

1

1

High-throughput

0.541

High

746127

SFT2
Protein transport protein SFT2

1

3

High-throughput

0.541

High

746134

AKR1
Palmitoyltransferase AKR1

1

7

High-throughput

0.536

High

746132

YPT35
Endosomal/vacuolar adapter protein YPT35

1

0

Small-scale

0.518

High

376281

YPT1
GTP-binding protein YPT1

1

11

High-throughput

0.508

High

746130

YPT31
GTP-binding protein YPT31/YPT8

1

16

High-throughput

0.508

High

746122

VAM7
Vacuolar morphogenesis protein 7

1

20

Small-scale

0.501

High

746151

VPS54
Vacuolar protein sorting-associated protein 54

1

2

Small-scale

0.481

High

746138

SFT1
Protein transport protein SFT1

1

0

Small-scale

0.480

High

582433

SEC23
Protein transport protein SEC23

1

4

High-throughput

0.479

High

616404

SEC18
Vesicular-fusion protein SEC18

1

20

Small-scale

0.479

High

646645

VPS15
Serine/threonine-protein kinase VPS15

1

5

High-throughput

0.479

High

649806

VPS34
Phosphatidylinositol 3-kinase VPS34

1

1

High-throughput

0.479

High

672635

BPH1
Beige protein homolog 1

1

3

High-throughput

0.479

High

743656

PEP7
Vacuolar segregation protein PEP7

1

8

Small-scale

0.479

High

746128

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.479

High

746137

SEC24
Protein transport protein SEC24

1

4

High-throughput

0.479

High

746139

ATG27
Autophagy-related protein 27

1

1

High-throughput

0.479

High

746142

VATG
V-type proton ATPase subunit G

1

2

High-throughput

0.479

High

746146

ENT5
Epsin-5

1

4

Small-scale

0.479

High

746150

ATG23
Autophagy-related protein 23

1

1

High-throughput

0.479

High

550574

SST2
Protein SST2

1

1

Small-scale

0.464

High

746129

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.458

High

746144

BECN1
Vacuolar protein sorting-associated protein 30

1

0

High-throughput

0.458

High

746148

SPO20
Sporulation-specific protein 20

1

0

Small-scale

0.458

High

746156

ATG11
Autophagy-related protein 11

1

0

High-throughput

0.458

High

746135

VPS8
Vacuolar protein sorting-associated protein 8

1

1

Small-scale

0.457

High

420901

PMA1
Plasma membrane ATPase 1

1

3

Small-scale

0.445

High

544273

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

618854

GAP1
General amino-acid permease GAP1

1

9

Small-scale

0.445

High

741243

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

705148

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

706602

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

746124

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.437

High

746149

SEC13
Protein transport protein SEC13

1

2

High-throughput

0.437

High

746143

IPI3
Pre-rRNA-processing protein IPI3

1

2

High-throughput

0.417

High

746126

MID2
Cell wall integrity sensor MID2

1

3

Small-scale

0.407

High

746140

YJY5
Uncharacterized endoplasmic reticulum membrane protein YJR015W

1

0

High-throughput

0.282

High

672387

STE50
Protein STE50

1

0

High-throughput

0.238

Low

700082

PRP45
Pre-mRNA-processing protein 45

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025