Protein: TLG2
t-SNARE affecting a late Golgi compartment protein 2 (Syntaxin TLG2)

Gene: TLG2
Organism: Saccharomyces cerevisiae S288C
Interactions: 73
UniProt ID: Q08144

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005802 - trans-Golgi network
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

807878

VPS45
Vacuolar protein sorting-associated protein 45

9

20

Small-scale

0.973

High

1046459

VTI1
t-SNARE VTI1

5

20

Small-scale

0.929

High

743485

SEC17
Alpha-soluble NSF attachment protein

3

20

Small-scale

0.854

High

779517

YKT6
Synaptobrevin homolog YKT6

2

20

Small-scale

0.737

High

1042341

TLG1
t-SNARE affecting a late Golgi compartment protein 1

6

20

Small-scale

0.731

High

1061944

VPS54
Vacuolar protein sorting-associated protein 54

3

1

Small-scale

0.669

High

751606

SNC2
Synaptobrevin homolog 2

1

20

Small-scale

0.665

High

746470

SSO1
Protein SSO1

1

18

Small-scale

0.618

High

1061942

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

16

Small-scale

0.618

High

1061947

GET3
ATPase GET3

2

2

Small-scale

0.603

High

1061946

ATG9
Autophagy-related protein 9

2

4

High-throughput

0.584

High

724275

SNC1
Synaptobrevin homolog 1

1

20

Small-scale

0.575

High

803103

GOSR1
Golgi SNAP receptor complex member 1

1

20

Small-scale

0.575

High

536179

ARF1
ADP-ribosylation factor 1

2

10

Small-scale

0.571

High

863832

ATG27
Autophagy-related protein 27

2

1

Small-scale

0.571

High

393433

HSP82
ATP-dependent molecular chaperone HSP82

2

8

High-throughput

0.562

High

1044010

ENT5
Epsin-5

1

4

Small-scale

0.561

High

805445

BZZ1
Protein BZZ1

1

4

High-throughput

0.541

High

441279

KAPA
cAMP-dependent protein kinase type 1

1

1

Small-scale

0.501

High

794806

SFT2
Protein transport protein SFT2

1

3

Small-scale

0.479

High

795565

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.479

High

864698

VPS53
Vacuolar protein sorting-associated protein 53

1

1

Small-scale

0.479

High

1056389

ATG23
Autophagy-related protein 23

1

1

High-throughput

0.479

High

1056561

IMH1
Golgin IMH1

1

4

Small-scale

0.479

High

550606

SST2
Protein SST2

1

1

Small-scale

0.464

High

818428

DDI1
DNA damage-inducible protein 1

1

0

Small-scale

0.458

High

919336

BTN2
Protein BTN2

1

0

Small-scale

0.458

High

633515

PP11
Serine/threonine-protein phosphatase PP1-1

1

4

Small-scale

0.457

High

376348

YPT1
GTP-binding protein YPT1

1

11

Small-scale

0.445

High

458611

SEC4
Ras-related protein SEC4

1

12

Small-scale

0.445

High

525352

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

527846

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

546522

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

633580

SAR1
Small COPII coat GTPase SAR1

1

20

Small-scale

0.445

High

671185

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

698126

PEP3
Vacuolar membrane protein PEP3

1

16

Small-scale

0.445

High

698158

KRE2
Glycolipid 2-alpha-mannosyltransferase

1

3

Small-scale

0.445

High

698195

KTR1
Alpha-1,2 mannosyltransferase KTR1

1

3

Small-scale

0.445

High

735761

VA0D
V-type proton ATPase subunit d

1

1

Small-scale

0.445

High

746247

PTM1
Membrane protein PTM1

1

2

Small-scale

0.445

High

779672

YPT52
GTP-binding protein YPT52

1

18

Small-scale

0.445

High

790348

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

4

Small-scale

0.445

High

800398

YPT31
GTP-binding protein YPT31/YPT8

1

16

Small-scale

0.445

High

809138

AKR1
Palmitoyltransferase AKR1

1

7

Small-scale

0.445

High

819967

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

909771

YPT32
GTP-binding protein YPT32/YPT11

1

16

Small-scale

0.445

High

705230

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

708365

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

733829

VPS10
Vacuolar protein sorting/targeting protein VPS10

1

0

Small-scale

0.426

High

782629

TVP38
Golgi apparatus membrane protein TVP38

1

0

Small-scale

0.426

High

808342

TVP23
Golgi apparatus membrane protein TVP23

1

0

Small-scale

0.426

High

813614

ERP2
Protein ERP2

1

0

Small-scale

0.426

High

825982

GVP36
Protein GVP36

1

0

Small-scale

0.426

High

922206

PRA1
Prenylated Rab acceptor 1

1

0

Small-scale

0.426

High

1042450

TRS31
Trafficking protein particle complex subunit 31

1

0

Small-scale

0.426

High

1044206

TVP15
Golgi apparatus membrane protein TVP15

1

0

Small-scale

0.426

High

1048343

TVP18
Golgi apparatus membrane protein TVP18

1

0

Small-scale

0.426

High

1061945

GNT1
Glucose N-acetyltransferase 1

1

0

Small-scale

0.426

High

794061

KTR3
Probable mannosyltransferase KTR3

1

3

Small-scale

0.407

High

794069

KTR4
Probable mannosyltransferase KTR4

1

3

Small-scale

0.407

High

780806

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

2

0

High-throughput

0.305

High

830046

PMP2
Plasma membrane ATPase proteolipid 2

1

0

High-throughput

0.282

High

1061943

GAS4
1,3-beta-glucanosyltransferase GAS4

1

0

High-throughput

0.282

High

817097

RPN3
26S proteasome regulatory subunit RPN3

1

0

High-throughput

0.269

Low

827105

GST1
Glutathione S-transferase 1

1

0

High-throughput

0.265

Low

402137

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.249

Low

918276

THG1
tRNA(His) guanylyltransferase

1

0

High-throughput

0.238

Low

569423

DPM1
Dolichol-phosphate mannosyltransferase

1

0

Small-scale

0.232

Low

797566

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

1

0

Small-scale

0.232

Low

863593

MNN5
Alpha-1,2-mannosyltransferase MNN5

1

0

Small-scale

0.232

Low

871574

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low

1059583

SNA4
Protein SNA4

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025