HitPredict

Interactor 1: SKP2 (Q13309)
S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2)
Gene: SKP2

Interactor 2: TTC9C (Q8N5M4)
Tetratricopeptide repeat protein 9C (TPR repeat protein 9C)
Gene: TTC9C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 424 Hs			1 171
+	Hs
		1031298 SKP2_HUMAN (1-424): 3e-94: 291: 100.00		FKBPL_HUMAN (3-171): 1.03e-31: 118: 23.08
+	Hs
		1031262 SKP2_HUMAN (1-424): 3e-94: 291: 100.00		Q9BPW0_HUMAN (2-163): 2.01e-30: 116: 14.20
+	Mm
		1141211 FBX41_MOUSE (33-365): 1.03e-54: 196: 17.92		PPP5_MOUSE (2-163): 1.11e-30: 117: 14.82
+	Hs
		1230759 FXL14_HUMAN (160-393): 1.49e-25: 109: 19.11		TTC9C_HUMAN (1-171): 1e-38: 131: 100.00
+	Hs
		1034926 FXL14_HUMAN (160-393): 1.49e-25: 109: 19.11		FKBP5_HUMAN (2-170): 3.75e-33: 123: 21.30
+	Hs
		1234876 FBXL4_HUMAN (159-424): 6.37e-15: 78.6: 17.73		TTC9C_HUMAN (1-171): 1e-38: 131: 100.00
+	Hs
		1053249 FBXL4_HUMAN (159-424): 6.37e-15: 78.6: 17.73		FKBP8_HUMAN (2-171): 1.63e-30: 115: 26.47