Protein: PGAM1
Phosphoglycerate mutase 1 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B)

Gene: PGAM1
Organism: Homo sapiens
Interactions: 167
UniProt ID: P18669

Gene Ontology (top 5):
GO:0004082 - bisphosphoglycerate mutase activity
GO:0004619 - phosphoglycerate mutase activity
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

582069

PGAM2
Phosphoglycerate mutase 2

7

14

High-throughput

0.960

High

616201

PGAM4
Probable phosphoglycerate mutase 4

4

14

High-throughput

0.873

High

459831

PMGE
Bisphosphoglycerate mutase

1

14

High-throughput

0.691

High

240706

PRKN
E3 ubiquitin-protein ligase parkin

4

6

High-throughput

0.686

High

529040

TAU
Microtubule-associated protein tau

2

5

High-throughput

0.628

High

421465

A4
Amyloid-beta precursor protein

2

2

Small-scale

0.628

High

563160

CFTR
Cystic fibrosis transmembrane conductance regulator

2

3

High-throughput

0.601

High

616198

UN5CL
UNC5C-like protein

2

0

High-throughput

0.580

High

550829

PCNA
Proliferating cell nuclear antigen

1

1

Small-scale

0.578

High

410604

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

2

High-throughput

0.576

High

557845

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.541

High

616152

ARL4D
ADP-ribosylation factor-like protein 4D

1

1

High-throughput

0.541

High

180698

TIF1A
Transcription intermediary factor 1-alpha

1

7

High-throughput

0.536

High

616145

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

616149

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

5

High-throughput

0.536

High

616215

CHPT1
Cholinephosphotransferase 1

1

1

High-throughput

0.536

High

616248

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.536

High

616216

S14L1
SEC14-like protein 1

1

1

High-throughput

0.515

High

616153

CEBPA
CCAAT/enhancer-binding protein alpha

2

2

Small-scale

0.514

High

135483

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.513

High

213801

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

385443

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.513

High

616172

KDSR
3-ketodihydrosphingosine reductase

1

0

High-throughput

0.513

High

616184

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

616210

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.513

High

616233

TX101
Testis-expressed protein 101

1

0

High-throughput

0.513

High

352945

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.493

High

484372

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

616142

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

2

High-throughput

0.489

High

136824

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

1

High-throughput

0.479

High

208460

PJA2
E3 ubiquitin-protein ligase Praja-2

1

3

Small-scale

0.479

High

315097

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

323164

TRI37
E3 ubiquitin-protein ligase TRIM37

1

10

High-throughput

0.479

High

361108

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.479

High

365292

PGK1
Phosphoglycerate kinase 1

1

3

High-throughput

0.479

High

447669

TPM3
Tropomyosin alpha-3 chain

1

1

High-throughput

0.479

High

476083

ANXA5
Annexin A5

1

2

High-throughput

0.479

High

578373

BRAF
Serine/threonine-protein kinase B-raf

1

1

High-throughput

0.479

High

606193

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

616129

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.479

High

616132

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

4

High-throughput

0.479

High

616133

PSA3
Proteasome subunit alpha type-3

1

4

Small-scale

0.479

High

616135

CALR
Calreticulin

1

1

High-throughput

0.479

High

616136

TKT
Transketolase

1

2

High-throughput

0.479

High

616137

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

616138

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

4

High-throughput

0.479

High

616139

PEBP1
Phosphatidylethanolamine-binding protein 1

1

3

High-throughput

0.479

High

616140

PDIA3
Protein disulfide-isomerase A3

1

6

High-throughput

0.479

High

616141

CDC27
Cell division cycle protein 27 homolog

1

1

Small-scale

0.479

High

616146

PPARG
Peroxisome proliferator-activated receptor gamma

1

2

Small-scale

0.479

High

616148

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

2

High-throughput

0.479

High

616150

YAP1
Transcriptional coactivator YAP1

1

6

High-throughput

0.479

High

616151

TCPE
T-complex protein 1 subunit epsilon

1

7

High-throughput

0.479

High

616155

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

616158

COPA
Coatomer subunit alpha

1

1

High-throughput

0.479

High

616161

RAB25
Ras-related protein Rab-25

1

2

High-throughput

0.479

High

616162

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.479

High

616164

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

1

Small-scale

0.479

High

616166

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

616167

1433Z
14-3-3 protein zeta/delta

1

18

High-throughput

0.479

High

616168

BASP1
Brain acid soluble protein 1

1

1

High-throughput

0.479

High

616170

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

616173

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.479

High

616176

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

616177

CUL3
Cullin-3

1

1

High-throughput

0.479

High

616178

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.479

High

616179

DX39B
Spliceosome RNA helicase DDX39B

1

2

High-throughput

0.479

High

616181

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

5

High-throughput

0.479

High

616189

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.479

High

616191

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.479

High

616192

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

616194

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

616197

ARHGP
Rho guanine nucleotide exchange factor 25

1

4

High-throughput

0.479

High

616204

TXND5
Thioredoxin domain-containing protein 5

1

7

High-throughput

0.479

High

616205

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

616211

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

616217

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

616218

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

2

High-throughput

0.479

High

616220

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

616225

ASB16
Ankyrin repeat and SOCS box protein 16

1

1

High-throughput

0.479

High

616227

KI20B
Kinesin-like protein KIF20B

1

1

High-throughput

0.479

High

616230

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.479

High

616232

NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit

1

2

High-throughput

0.479

High

616236

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

616237

KI13B
Kinesin-like protein KIF13B

1

1

High-throughput

0.479

High

616242

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

616243

ATIF1
ATPase inhibitor, mitochondrial

1

1

High-throughput

0.479

High

616245

TLN1
Talin-1

1

3

High-throughput

0.479

High

616246

NDK7
Nucleoside diphosphate kinase homolog 7

1

1

High-throughput

0.479

High

616247

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.479

High

129988

PGRC1
Membrane-associated progesterone receptor component 1

1

0

Small-scale

0.458

High

321433

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.458

High

345353

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

424351

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.458

High

459450

PROF1
Profilin-1

1

0

High-throughput

0.458

High

570828

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

599532

STMN1
Stathmin

1

0

High-throughput

0.458

High

616131

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

616147

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

616154

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.458

High

616157

STC1
Stanniocalcin-1

1

0

High-throughput

0.458

High

616160

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

616174

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.458

High

616175

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.458

High

616183

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

616186

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

616188

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.458

High

616193

ANR11
Ankyrin repeat domain-containing protein 11

1

0

High-throughput

0.458

High

616196

CASZ1
Zinc finger protein castor homolog 1

1

0

High-throughput

0.458

High

616200

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

616202

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

616206

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

616207

ABCF1
ATP-binding cassette sub-family F member 1

1

0

High-throughput

0.458

High

616208

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

616212

LRC8C
Volume-regulated anion channel subunit LRRC8C

1

0

High-throughput

0.458

High

616214

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

616219

RYR2
Ryanodine receptor 2

1

0

High-throughput

0.458

High

616221

ASB9
Ankyrin repeat and SOCS box protein 9

1

0

High-throughput

0.458

High

616222

MACIR
Macrophage immunometabolism regulator

1

0

High-throughput

0.458

High

616228

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.458

High

616234

AICDA
Single-stranded DNA cytosine deaminase

1

0

Small-scale

0.458

High

616235

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

616238

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

616239

HYPK
Huntingtin-interacting protein K

1

0

Small-scale

0.458

High

616240

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

616241

HDAC6
Protein deacetylase HDAC6

1

0

High-throughput

0.458

High

616244

DS13B
Dual specificity protein phosphatase 13B

1

0

High-throughput

0.458

High

616249

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

0

High-throughput

0.458

High

616180

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.457

High

616229

PKP4
Plakophilin-4

1

1

High-throughput

0.457

High

184576

MK13
Mitogen-activated protein kinase 13

1

2

Small-scale

0.445

High

583444

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

2

High-throughput

0.445

High

616143

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.445

High

616159

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.445

High

616165

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.445

High

107317

F8VWT9
HECT domain E3 ubiquitin protein ligase 4

1

6

High-throughput

0.437

High

259416

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.437

High

286428

WBP4
WW domain-binding protein 4

1

1

High-throughput

0.437

High

411325

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.437

High

566545

PDIA4
Protein disulfide-isomerase A4

1

7

High-throughput

0.437

High

587881

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

616134

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

616144

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

616163

SUMO2
Small ubiquitin-related modifier 2

1

4

High-throughput

0.437

High

616169

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

4

High-throughput

0.437

High

616185

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.437

High

616195

KCTD9
BTB/POZ domain-containing protein KCTD9

1

1

High-throughput

0.437

High

616203

UN13C
Protein unc-13 homolog C

1

4

High-throughput

0.437

High

616223

GRM2B
GRAM domain-containing protein 2B

1

2

High-throughput

0.437

High

616226

CASD1
N-acetylneuraminate

1

2

High-throughput

0.437

High

616231

PCGF1
Polycomb group RING finger protein 1

1

5

High-throughput

0.437

High

419958

B3A2
Anion exchange protein 2

1

0

High-throughput

0.426

High

616213

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

0

High-throughput

0.426

High

429274

JUN
Transcription factor Jun

1

2

High-throughput

0.407

High

616171

P
P protein

1

1

High-throughput

0.407

High

76614

B4DZK1
cDNA FLJ50036, weakly similar to Myosin-11

1

0

High-throughput

0.249

Low

105297

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

571367

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low

616130

PTMS
Parathymosin

1

0

High-throughput

0.249

Low

616182

RBM39
RNA-binding protein 39

1

0

High-throughput

0.249

Low

616187

Z385B
Zinc finger protein 385B

1

0

High-throughput

0.249

Low

616190

MGLYR
Metabotropic glycine receptor

1

0

High-throughput

0.249

Low

616224

THOC3
THO complex subunit 3

1

0

Small-scale

0.249

Low

516817

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.232

Low

616156

GPC3
Glypican-3

1

0

High-throughput

0.232

Low

616199

S41A1
Solute carrier family 41 member 1

1

0

High-throughput

0.232

Low

616209

MFSD8
Major facilitator superfamily domain-containing protein 8

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025