Interactor 1: SKP2 (Q13309)
S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2)
Gene: SKP2

Interactor 2: FXL18 (Q96ME1)
F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18)
Gene: FBXL18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box-like~F-box-like
Common GO terms GO:0005829 - cytosol
GO:0019005 - SCF ubiquitin ligase complex
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 424
Hs

1 718
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024