HitPredict

Interactor 1: SKP2 (Q13309)
S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2)
Gene: SKP2

Interactor 2: RN126 (Q9BV68)
E3 ubiquitin-protein ligase RNF126 (EC 2.3.2.27) (RING finger protein 126)
Gene: RNF126

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0070534 - protein K63-linked ubiquitination and 2 others more... GO:0070936 - protein K48-linked ubiquitination GO:1905168 - positive regulation of double-strand break repair via homologous recombination
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	424
Hs

1	311

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024