Protein: FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12 (PPIase Fkbp12) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (Macrolide-binding protein) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)

Gene: FKB12, Fkbp12
Organism: Drosophila melanogaster
Interactions: 188
UniProt ID: P48375

Gene Ontology (top 5):
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0033017 - sarcoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

668103

PPIA
Peptidyl-prolyl cis-trans isomerase

2

6

High-throughput

0.737

High

871650

Q9V3V2
peptidylprolyl isomerase

2

14

High-throughput

0.737

High

871675

Q9VGK3
peptidylprolyl isomerase

2

14

High-throughput

0.737

High

871697

Q9VPN5
Stress-induced-phosphoprotein 1

2

14

High-throughput

0.737

High

871732

Q9W227
Peptidyl-prolyl cis-trans isomerase

2

11

High-throughput

0.737

High

356311

O97102
Small ubiquitin-related modifier

2

6

High-throughput

0.659

High

871747

X2JD70
Troponin C at 25D, isoform B

1

4

High-throughput

0.618

High

234547

VINC
Vinculin

2

4

High-throughput

0.594

High

871672

FLNA
Filamin-A

2

3

High-throughput

0.594

High

262656

LOK
Ovarian-specific serine/threonine-protein kinase Lok

1

5

High-throughput

0.575

High

871604

CALM
Calmodulin

1

4

High-throughput

0.575

High

871688

FKB59
FK506-binding protein 59

1

19

High-throughput

0.575

High

871729

Q9W0H8
Reticulocalbin-3

1

11

High-throughput

0.575

High

195009

O16043
Anon1A4

2

3

High-throughput

0.571

High

357475

INO1
Inositol-3-phosphate synthase

2

3

High-throughput

0.571

High

460005

ALF
Fructose-bisphosphate aldolase

2

3

High-throughput

0.571

High

476914

NDKA
Nucleoside diphosphate kinase

2

5

High-throughput

0.571

High

578048

ENO
Enolase

2

4

High-throughput

0.571

High

609369

PCNA
Proliferating cell nuclear antigen

2

3

High-throughput

0.571

High

649012

ANX10
Annexin B10

2

8

High-throughput

0.571

High

762519

UCHL
Ubiquitin carboxyl-terminal hydrolase

2

7

High-throughput

0.571

High

855973

MOEH
Moesin/ezrin/radixin homolog 1

2

5

High-throughput

0.571

High

871599

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

2

3

High-throughput

0.571

High

871600

PDI
Protein disulfide-isomerase

2

16

High-throughput

0.571

High

871603

SODC
Superoxide dismutase [Cu-Zn]

2

3

High-throughput

0.571

High

871613

NLP
Nucleoplasmin-like protein

2

7

High-throughput

0.571

High

871617

Q7JX87
1-Cys peroxiredoxin

2

7

High-throughput

0.571

High

871628

Q8IRD3
Glutathione peroxidase

2

3

High-throughput

0.571

High

871632

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

2

3

High-throughput

0.571

High

871637

NACA
Nascent polypeptide-associated complex subunit alpha

2

5

High-throughput

0.571

High

871647

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

2

3

High-throughput

0.571

High

871653

THIO2
Thioredoxin-2

2

11

High-throughput

0.571

High

871671

Q9VEB1
Malate dehydrogenase, mitochondrial

2

3

High-throughput

0.571

High

871678

TEBPH
Cytosolic Prostaglandin E synthase

2

8

High-throughput

0.571

High

871698

Q9VPX6
Adenylyl cyclase-associated protein

2

3

High-throughput

0.571

High

871706

Q9VSL2
Glutathione S transferase O3

2

7

High-throughput

0.571

High

871710

Q9VTY2
Uncharacterized protein, isoform A

2

19

High-throughput

0.571

High

197739

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

2

3

High-throughput

0.521

High

304602

RS21
Small ribosomal subunit protein eS21

2

3

High-throughput

0.521

High

712326

CALR
Calreticulin

2

4

High-throughput

0.521

High

871611

ATPB
ATP synthase subunit beta, mitochondrial

2

7

High-throughput

0.521

High

871620

Q7K2K2
FI04612p

2

3

High-throughput

0.521

High

871648

CP2B
Cardio acceleratory peptide 2b

2

2

High-throughput

0.521

High

871686

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

2

5

High-throughput

0.521

High

871699

BACC
Bacchus

2

3

High-throughput

0.521

High

871711

Q9VU35
10 kDa heat shock protein, mitochondrial

2

3

High-throughput

0.521

High

871728

Q9W022
GEO01508p1

2

14

High-throughput

0.521

High

871662

Q9VAY2
Heat shock protein 83

1

18

High-throughput

0.514

High

611470

PSA4
Proteasome subunit alpha type-4

1

9

High-throughput

0.508

High

711010

CSW
Tyrosine-protein phosphatase corkscrew

1

2

High-throughput

0.508

High

871636

ENA
Protein enabled

1

2

High-throughput

0.508

High

871640

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

2

High-throughput

0.508

High

871661

Q9VAU6
LD27564p

1

0

High-throughput

0.486

High

871733

OR9A
Odorant receptor 9a

1

0

High-throughput

0.486

High

871629

Q8IRS7
Ciboulot, isoform C

1

6

High-throughput

0.479

High

871676

Q9VGM2
Fatty acid-binding protein, muscle

1

7

High-throughput

0.479

High

871713

PYRG
CTP synthase

1

1

High-throughput

0.479

High

871634

Q8T0I9
GH27479p

1

1

High-throughput

0.464

High

871646

TITIN
Titin

1

1

High-throughput

0.464

High

871670

Q9VEA1
Eukaryotic translation initiation factor 4C

1

0

High-throughput

0.458

High

871723

BTHD
Selenoprotein BthD

1

0

High-throughput

0.458

High

53980

A1Z892
1-Cys peroxiredoxin

1

7

High-throughput

0.445

High

57530

A1ZB71
Glutathione S transferase E6

1

10

High-throughput

0.445

High

57753

A1ZB77
Uncharacterized protein, isoform J

1

3

High-throughput

0.445

High

121192

ALDR
Aldo-keto reductase 1B

1

19

High-throughput

0.445

High

305639

IPYR
Inorganic pyrophosphatase

1

4

High-throughput

0.445

High

357263

O97428
Ciboulot, isoform A

1

6

High-throughput

0.445

High

458085

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.445

High

556647

PSA1
Proteasome subunit alpha type-1

1

8

High-throughput

0.445

High

648865

ANXB9
Annexin B9

1

8

High-throughput

0.445

High

682715

PROF
Profilin

1

4

High-throughput

0.445

High

709526

1433Z
14-3-3 protein zeta

1

5

High-throughput

0.445

High

821818

PSA2
Proteasome subunit alpha type-2

1

8

High-throughput

0.445

High

835125

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

5

High-throughput

0.445

High

871596

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

3

High-throughput

0.445

High

871601

VATE
V-type proton ATPase subunit E

1

3

High-throughput

0.445

High

871607

TRXR1
Thioredoxin reductase 1, mitochondrial

1

7

High-throughput

0.445

High

871608

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.445

High

871609

PGK
Phosphoglycerate kinase

1

3

High-throughput

0.445

High

871615

Q76NR6
Regucalcin

1

6

High-throughput

0.445

High

871616

Q7JVH6
LD24696p

1

19

High-throughput

0.445

High

871619

Q7K148
Proteasome subunit beta

1

8

High-throughput

0.445

High

871621

TERA
Transitional endoplasmic reticulum ATPase TER94

1

6

High-throughput

0.445

High

871622

Q7KN99
Phosphopantothenoylcysteine synthetase, isoform A

1

3

High-throughput

0.445

High

871623

Q7KTW5
Inositol-1-monophosphatase

1

3

High-throughput

0.445

High

871626

Q8INK3
Fatty acid-binding protein, muscle

1

7

High-throughput

0.445

High

871627

Q8IQZ7
FI19014p1

1

4

High-throughput

0.445

High

871630

Q8MT58
Carnosine dipeptidase 2, isoform A

1

3

High-throughput

0.445

High

871631

Q8MYY7
RE44624p

1

18

High-throughput

0.445

High

871633

OLA1
Obg-like ATPase 1

1

6

High-throughput

0.445

High

871635

Q8T0L3
E1 ubiquitin-activating enzyme

1

4

High-throughput

0.445

High

871639

FAXC
Failed axon connections

1

3

High-throughput

0.445

High

871641

IF5A
Eukaryotic translation initiation factor 5A

1

4

High-throughput

0.445

High

871642

JUPIT
Microtubule-associated protein Jupiter

1

3

High-throughput

0.445

High

871644

Q9I7K7
Arrestin C-terminal-like domain-containing protein

1

2

High-throughput

0.445

High

871645

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

3

High-throughput

0.445

High

871649

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

3

High-throughput

0.445

High

871655

PSA3
Proteasome subunit alpha type-3

1

13

High-throughput

0.445

High

871657

Q9VAC1
GM14349p

1

3

High-throughput

0.445

High

871658

Q9VAC4
GEO09167p1

1

7

High-throughput

0.445

High

871660

Q9VAN7
Phosphoglycerate mutase

1

4

High-throughput

0.445

High

871667

Q9VCK6
LD34157p

1

3

High-throughput

0.445

High

871668

Q9VD02
GH14779p

1

9

High-throughput

0.445

High

871677

TCTP
Translationally-controlled tumor protein homolog

1

3

High-throughput

0.445

High

871679

Q9VHN7
transketolase

1

6

High-throughput

0.445

High

871680

Q9VHX4
LD24679p

1

19

High-throughput

0.445

High

871682

Q9VIE8
Aconitate hydratase, mitochondrial

1

4

High-throughput

0.445

High

871683

Q9VKB0
threonine--tRNA ligase

1

6

High-throughput

0.445

High

871684

Q9VKW5
Prolyl endopeptidase

1

4

High-throughput

0.445

High

871685

EF1D
Probable elongation factor 1-delta

1

4

High-throughput

0.445

High

871689

Q9VLB7
Rab GDP dissociation inhibitor

1

4

High-throughput

0.445

High

871690

AK200
A-kinase anchor protein 200

1

4

High-throughput

0.445

High

871692

Q9VMU6
LD31822p

1

3

High-throughput

0.445

High

871693

GUAD
Guanine deaminase

1

2

High-throughput

0.445

High

871694

PSB4
Proteasome subunit beta type-4

1

20

High-throughput

0.445

High

871701

Q9VRD6
NTF2-related export protein

1

3

High-throughput

0.445

High

871702

Q9VRL1
GEO06356p1

1

4

High-throughput

0.445

High

871705

Q9VSI6
Isocitrate dehydrogenase [NADP]

1

3

High-throughput

0.445

High

871708

Q9VTX2
RE32936p

1

2

High-throughput

0.445

High

871712

Q9VUC1
Hsc70Cb, isoform A

1

12

High-throughput

0.445

High

871714

Y9705
Cold shock domain-containing protein CG9705

1

3

High-throughput

0.445

High

871717

Q9VW59
Rho GDP-dissociation inhibitor 3

1

3

High-throughput

0.445

High

871721

Q9VXQ3
Diphosphomevalonate decarboxylase

1

2

High-throughput

0.445

High

871722

CLIC
Chloride intracellular channel Clic

1

8

High-throughput

0.445

High

871730

SND1
Staphylococcal nuclease domain-containing protein 1

1

4

High-throughput

0.445

High

871735

Q9W3Y3
Calcyclin-binding protein

1

10

High-throughput

0.445

High

871737

WUHO
tRNA

1

7

High-throughput

0.445

High

871738

Q9W457
Serine hydroxymethyltransferase

1

3

High-throughput

0.445

High

871741

PSB3
Proteasome subunit beta type-3

1

14

High-throughput

0.445

High

871742

Q9XYZ9
Glutathione S transferase E12, isoform A

1

10

High-throughput

0.445

High

871743

Q9XZ57
Eb1, isoform E

1

3

High-throughput

0.445

High

871744

PSA6
Proteasome subunit alpha type-6

1

14

High-throughput

0.445

High

871745

PURA
Adenylosuccinate synthetase

1

3

High-throughput

0.445

High

871746

Q9Y112
BcDNA.GH10614

1

19

High-throughput

0.445

High

120753

M9PE30
Transgelin

1

8

High-throughput

0.437

High

871605

UBX
Homeotic protein ultrabithorax

1

2

High-throughput

0.437

High

871625

Q8IMG1
Uncharacterized protein, isoform C

1

4

High-throughput

0.437

High

871674

Q9VG51
Sorting nexin-3

1

2

High-throughput

0.437

High

871707

Q9VSZ3
LD31045p

1

3

High-throughput

0.437

High

871709

Q9VTY1
LD40136p

1

2

High-throughput

0.437

High

871725

Q9VYR1
Regucalcin

1

6

High-throughput

0.437

High

53837

A1Z864
FI01421p

1

2

High-throughput

0.407

High

86462

B9EQV3
Endoplasmic reticulum transmembrane protein

1

3

High-throughput

0.407

High

305178

TRMB
tRNA

1

3

High-throughput

0.407

High

871597

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.407

High

871606

CYC2
Cytochrome c-2

1

2

High-throughput

0.407

High

871610

HMGD
High mobility group protein D

1

4

High-throughput

0.407

High

871612

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

3

High-throughput

0.407

High

871614

Q3YMU0
Protein disulfide-isomerase

1

13

High-throughput

0.407

High

871618

Q7JXC4
CG6459 protein

1

3

High-throughput

0.407

High

871624

QPCT2
Glutaminyl-peptide cyclotransferase

1

2

High-throughput

0.407

High

871638

ACPM
Acyl carrier protein, mitochondrial

1

3

High-throughput

0.407

High

871643

NASP
Nuclear autoantigenic sperm protein homolog

1

3

High-throughput

0.407

High

871651

SPC25
Kinetochore protein Spc25

1

2

High-throughput

0.407

High

871652

Q9V3V9
Endonuclease G inhibitor, isoform A

1

3

High-throughput

0.407

High

871654

PDIA6
Protein disulfide-isomerase A6 homolog

1

12

High-throughput

0.407

High

871656

Q9V9U3
LD45254p

1

4

High-throughput

0.407

High

871659

Q9VAG3
trypsin

1

2

High-throughput

0.407

High

871663

Q9VBR6
RE74917p

1

4

High-throughput

0.407

High

871664

Q9VBT1
CHK kinase-like domain-containing protein

1

2

High-throughput

0.407

High

871666

ORN
Probable oligoribonuclease

1

2

High-throughput

0.407

High

871669

Q9VD29
small monomeric GTPase

1

5

High-throughput

0.407

High

871673

Q9VG33
Sulfurtransferase

1

3

High-throughput

0.407

High

871681

Q9VIC3
carboxylesterase

1

3

High-throughput

0.407

High

871687

Q9VL70
HL08109p

1

3

High-throughput

0.407

High

871695

Q9VNB2
RE42193p

1

3

High-throughput

0.407

High

871696

Q9VP52
GH24315p

1

2

High-throughput

0.407

High

871700

Q9VRD4
Uncharacterized protein, isoform A

1

5

High-throughput

0.407

High

871703

Q9VRP2
Uncharacterized protein, isoform A

1

5

High-throughput

0.407

High

871704

Q9VS98
LD12639p

1

2

High-throughput

0.407

High

871715

Q9VVL7
Dihydrolipoyl dehydrogenase

1

7

High-throughput

0.407

High

871718

Q9VW70
FI21813p1

1

2

High-throughput

0.407

High

871719

RS10B
Small ribosomal subunit protein eS10B

1

5

High-throughput

0.407

High

871720

DHB4
Peroxisomal multifunctional enzyme type 2

1

3

High-throughput

0.407

High

871724

Q9VYB9
LP02557p

1

2

High-throughput

0.407

High

871727

Q9VZI1
Transgelin

1

8

High-throughput

0.407

High

871734

Q9W3X6
fumarate hydratase

1

3

High-throughput

0.407

High

871736

CISY
Probable citrate synthase, mitochondrial

1

6

High-throughput

0.407

High

871739

Q9W478
RE43153p

1

3

High-throughput

0.407

High

871598

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.265

Low

871665

Q9VBU9
40S ribosomal protein S27

1

0

High-throughput

0.265

Low

871716

CP312
Probable cytochrome P450 312a1

1

0

High-throughput

0.265

Low

871602

COLL
Transcription factor collier

1

0

High-throughput

0.251

Low

662171

POXN
Paired box pox-neuro protein

1

0

High-throughput

0.249

Low

871691

TCP4
RNA polymerase II transcriptional coactivator

1

0

High-throughput

0.249

Low

871726

Q9VYT3
FI23714p1

1

0

Small-scale

0.249

Low

871731

Q9W0U6
Sulfatase-modifying factor enzyme-like domain-containing protein

1

0

High-throughput

0.249

Low

871740

Q9W4X1
GH07966p

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025