HitPredict

Interactor 1: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Interactor 2: IF4A2 (Q14240)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: EIF4A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 407
+	Hs
		892791 PABP4_HUMAN (1-644): 0: 585: 100.00		IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88
+	Hs
		516434 PABP1_HUMAN (1-644): 0: 542: 74.54		IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88
+	Hs
		134018 PABP4_HUMAN (1-644): 0: 585: 100.00		DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51
+	Hs
		133858 PABP1_HUMAN (1-644): 0: 542: 74.54		DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51
+	Hs
		516391 PABP1_HUMAN (1-644): 0: 542: 74.54		IF4A3_HUMAN (3-407): 2.28e-130: 382: 67.65
+	Hs
		516515 PABP1_HUMAN (1-644): 0: 542: 74.54		IF4A2_HUMAN (1-407): 2.49e-129: 380: 100.00
+	Sc
		376792 PABP_YEAST (2-290): 4.28e-66: 228: 30.07		DHH1_YEAST (33-403): 1.13e-98: 305: 43.67
+	Mm
		857295 TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12		IF4A1_MOUSE (3-407): 2.35e-159: 456: 89.88
+	Hs
		571302 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		DDX5_HUMAN (10-407): 3.86e-132: 394: 30.30
+	Tc
		1116214 Q4E4I9_TRYCC (2-304): 7.96e-61: 214: 29.19		Q4DIE1_TRYCC (35-400): 4.98e-88: 274: 39.51
+	Hs
		133876 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51
+	Mm
		857323 TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12		DDX17_MOUSE (25-407): 6.02e-132: 395: 31.20
+	Mm
		857351 TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12		Q8BTS0_MOUSE (22-407): 5.62e-132: 393: 30.96