Protein: YTHD3
YTH domain-containing family protein 3 (DF3)

Gene: YTHD3, YTHDF3
Organism: Homo sapiens
Interactions: 238
UniProt ID: Q7Z739

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1192369

YTHD1
YTH domain-containing family protein 1

4

9

High-throughput

0.892

High

1192420

YTHD2
YTH domain-containing family protein 2

3

8

High-throughput

0.827

High

1192409

FAF1
FAS-associated factor 1

4

3

High-throughput

0.684

High

1192334

TNIP2
TNFAIP3-interacting protein 2

2

2

High-throughput

0.611

High

328884

TOP3B
DNA topoisomerase 3-beta-1

2

2

High-throughput

0.601

High

1127634

PRC2B
Protein PRRC2B

2

12

High-throughput

0.586

High

1174812

LARP4
La-related protein 4

2

11

High-throughput

0.586

High

1192384

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

2

9

High-throughput

0.586

High

603579

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

3

High-throughput

0.584

High

1030326

G3BP1
Ras GTPase-activating protein-binding protein 1

2

8

High-throughput

0.584

High

1192322

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

5

High-throughput

0.584

High

1192380

RC3H2
Roquin-2

2

16

High-throughput

0.584

High

360098

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

1

High-throughput

0.571

High

374455

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

5

High-throughput

0.571

High

592344

RAB5A
Ras-related protein Rab-5A

2

1

High-throughput

0.571

High

1046411

PTK6
Protein-tyrosine kinase 6

2

4

High-throughput

0.571

High

841253

CDK7
Cyclin-dependent kinase 7

2

0

High-throughput

0.547

High

509042

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.536

High

529348

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

539812

IDE
Insulin-degrading enzyme

1

1

High-throughput

0.536

High

649580

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.536

High

801221

KI67
Proliferation marker protein Ki-67

1

7

High-throughput

0.536

High

1192340

PSPC1
Paraspeckle component 1

1

12

High-throughput

0.536

High

1192360

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

5

High-throughput

0.536

High

553068

RFA2
Replication protein A 32 kDa subunit

2

6

High-throughput

0.533

High

651571

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

4

High-throughput

0.533

High

720809

RFA3
Replication protein A 14 kDa subunit

2

5

High-throughput

0.533

High

205598

TGON2
Trans-Golgi network integral membrane protein 2

2

3

High-throughput

0.521

High

155387

NRP1
Neuropilin-1

1

3

High-throughput

0.515

High

316928

KLF8
Krueppel-like factor 8

1

9

High-throughput

0.500

High

972341

TIE2
Angiopoietin-1 receptor

1

13

High-throughput

0.500

High

1018333

MERTK
Tyrosine-protein kinase Mer

1

13

High-throughput

0.500

High

1192321

ZDH17
Palmitoyltransferase ZDHHC17

1

10

High-throughput

0.494

High

364331

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.493

High

198921

RFOX2
RNA binding protein fox-1 homolog 2

1

12

High-throughput

0.481

High

446690

SNRPA
U1 small nuclear ribonucleoprotein A

1

18

High-throughput

0.481

High

929221

RS21
Small ribosomal subunit protein eS21

1

1

High-throughput

0.481

High

1052241

SRC8
Src substrate cortactin

1

4

High-throughput

0.481

High

1075682

SF01
Splicing factor 1

1

9

High-throughput

0.481

High

1192323

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

6

High-throughput

0.481

High

1192326

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

9

High-throughput

0.481

High

1192358

QKI
KH domain-containing RNA-binding protein QKI

1

7

High-throughput

0.481

High

1192392

RBM22
Pre-mRNA-splicing factor RBM22

1

9

High-throughput

0.481

High

47801

RBM47
RNA-binding protein 47

1

14

High-throughput

0.479

High

50023

MEX3A
RNA-binding protein MEX3A

1

17

High-throughput

0.479

High

61401

CNOT1
CCR4-NOT transcription complex subunit 1

1

3

High-throughput

0.479

High

122852

MEN1
Menin

1

2

High-throughput

0.479

High

125551

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.479

High

134102

DDX3X
ATP-dependent RNA helicase DDX3X

1

2

High-throughput

0.479

High

162931

XPO1
Exportin-1

1

8

High-throughput

0.479

High

166269

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.479

High

216942

KIF1C
Kinesin-like protein KIF1C

1

8

High-throughput

0.479

High

235930

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

14

High-throughput

0.479

High

257371

CNOT3
CCR4-NOT transcription complex subunit 3

1

13

High-throughput

0.479

High

257641

ANR17
Ankyrin repeat domain-containing protein 17

1

6

High-throughput

0.479

High

264344

GGYF1
GRB10-interacting GYF protein 1

1

4

High-throughput

0.479

High

269014

CSDE1
Cold shock domain-containing protein E1

1

2

High-throughput

0.479

High

317672

CNOT4
CCR4-NOT transcription complex subunit 4

1

2

High-throughput

0.479

High

322817

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

347190

MYC
Myc proto-oncogene protein

1

10

High-throughput

0.479

High

387009

P53
Cellular tumor antigen p53

1

5

High-throughput

0.479

High

398019

ISG15
Ubiquitin-like protein ISG15

1

4

High-throughput

0.479

High

442277

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

18

High-throughput

0.479

High

516575

PABP1
Polyadenylate-binding protein 1

1

8

High-throughput

0.479

High

569843

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

611461

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

9

Small-scale

0.479

High

640524

DDX6
Probable ATP-dependent RNA helicase DDX6

1

6

High-throughput

0.479

High

644280

TTP
mRNA decay activator protein ZFP36

1

5

High-throughput

0.479

High

668378

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

16

High-throughput

0.479

High

668793

PML
Protein PML

1

8

High-throughput

0.479

High

717974

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.479

High

718958

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

749631

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.479

High

779669

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

820960

PRC2A
Protein PRRC2A

1

15

High-throughput

0.479

High

832558

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

843766

FXR1
RNA-binding protein FXR1

1

11

High-throughput

0.479

High

844124

FXR2
RNA-binding protein FXR2

1

11

High-throughput

0.479

High

892841

IF4A1
Eukaryotic initiation factor 4A-I

1

5

High-throughput

0.479

High

893073

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

941998

IF4G2
Eukaryotic translation initiation factor 4 gamma 2

1

2

High-throughput

0.479

High

959504

VIGLN
Vigilin

1

14

High-throughput

0.479

High

963542

TIAR
Nucleolysin TIAR

1

6

High-throughput

0.479

High

966585

OTUD4
OTU domain-containing protein 4

1

6

High-throughput

0.479

High

969813

KIF23
Kinesin-like protein KIF23

1

6

High-throughput

0.479

High

988977

FMR1
Fragile X messenger ribonucleoprotein 1

1

11

High-throughput

0.479

High

1016208

FOXO1
Forkhead box protein O1

1

3

High-throughput

0.479

High

1017943

GRSF1
G-rich sequence factor 1

1

12

High-throughput

0.479

High

1031376

PABP4
Polyadenylate-binding protein 4

1

8

High-throughput

0.479

High

1049830

UBP2L
Ubiquitin-associated protein 2-like

1

10

High-throughput

0.479

High

1053908

CAPR1
Caprin-1

1

5

High-throughput

0.479

High

1056682

PUM1
Pumilio homolog 1

1

5

High-throughput

0.479

High

1058236

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

5

High-throughput

0.479

High

1065000

R3HD1
R3H domain-containing protein 1

1

10

High-throughput

0.479

High

1066325

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.479

High

1073785

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

16

High-throughput

0.479

High

1080701

ZYX
Zyxin

1

1

High-throughput

0.479

High

1089520

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

13

High-throughput

0.479

High

1109597

LSM12
Protein LSM12

1

2

High-throughput

0.479

High

1119439

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

6

High-throughput

0.479

High

1121064

GLE1
mRNA export factor GLE1

1

7

High-throughput

0.479

High

1123119

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

2

High-throughput

0.479

High

1129563

SMAG2
Protein Smaug homolog 2

1

1

High-throughput

0.479

High

1130264

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.479

High

1134102

UBAP2
Ubiquitin-associated protein 2

1

12

High-throughput

0.479

High

1135080

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

2

High-throughput

0.479

High

1135871

TUT4
Terminal uridylyltransferase 4

1

4

High-throughput

0.479

High

1136147

RC3H1
Roquin-1

1

9

High-throughput

0.479

High

1158075

DHX57
Putative ATP-dependent RNA helicase DHX57

1

2

High-throughput

0.479

High

1159049

CEP85
Centrosomal protein of 85 kDa

1

11

High-throughput

0.479

High

1168771

MEX3B
RNA-binding protein MEX3B

1

4

High-throughput

0.479

High

1170604

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

1184185

MEPCE
7SK snRNA methylphosphate capping enzyme

1

2

High-throughput

0.479

High

1187639

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

9

High-throughput

0.479

High

1192316

PATL1
Protein PAT1 homolog 1

1

10

High-throughput

0.479

High

1192317

ZN598
E3 ubiquitin-protein ligase ZNF598

1

4

High-throughput

0.479

High

1192318

EST1A
Telomerase-binding protein EST1A

1

6

High-throughput

0.479

High

1192319

TAXB1
Tax1-binding protein 1

1

6

High-throughput

0.479

High

1192320

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

11

High-throughput

0.479

High

1192324

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

1192325

DCP1B
mRNA-decapping enzyme 1B

1

6

High-throughput

0.479

High

1192327

SERB1
SERPINE1 mRNA-binding protein 1

1

4

High-throughput

0.479

High

1192328

FA98A
Protein FAM98A

1

1

High-throughput

0.479

High

1192329

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

1

High-throughput

0.479

High

1192331

LS14A
Protein LSM14 homolog A

1

8

High-throughput

0.479

High

1192332

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

10

High-throughput

0.479

High

1192333

NUP35
Nucleoporin NUP35

1

2

High-throughput

0.479

High

1192335

PUM2
Pumilio homolog 2

1

5

High-throughput

0.479

High

1192337

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

1192338

SMAP2
Stromal membrane-associated protein 2

1

2

High-throughput

0.479

High

1192343

DDX1
ATP-dependent RNA helicase DDX1

1

4

High-throughput

0.479

High

1192344

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

6

High-throughput

0.479

High

1192345

CNOT9
CCR4-NOT transcription complex subunit 9

1

4

High-throughput

0.479

High

1192346

LAR4B
La-related protein 4B

1

9

High-throughput

0.479

High

1192347

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.479

High

1192348

CELF1
CUGBP Elav-like family member 1

1

9

High-throughput

0.479

High

1192349

RENT1
Regulator of nonsense transcripts 1

1

5

High-throughput

0.479

High

1192350

DAZL
Deleted in azoospermia-like

1

12

High-throughput

0.479

High

1192353

FUBP3
Far upstream element-binding protein 3

1

11

High-throughput

0.479

High

1192354

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

4

High-throughput

0.479

High

1192355

CEP19
Centrosomal protein of 19 kDa

1

2

High-throughput

0.479

High

1192359

SMG1
Serine/threonine-protein kinase SMG1

1

1

High-throughput

0.479

High

1192361

SEBP2
Selenocysteine insertion sequence-binding protein 2

1

2

High-throughput

0.479

High

1192362

ATX2
Ataxin-2

1

8

High-throughput

0.479

High

1192363

B9D2
B9 domain-containing protein 2

1

3

High-throughput

0.479

High

1192364

TRI56
E3 ubiquitin-protein ligase TRIM56

1

9

High-throughput

0.479

High

1192365

LS14B
Protein LSM14 homolog B

1

4

High-throughput

0.479

High

1192367

SCAPE
S phase cyclin A-associated protein in the endoplasmic reticulum

1

8

High-throughput

0.479

High

1192370

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

8

High-throughput

0.479

High

1192371

UNK
RING finger protein unkempt homolog

1

10

High-throughput

0.479

High

1192372

ZCHC2
Zinc finger CCHC domain-containing protein 2

1

2

High-throughput

0.479

High

1192373

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

2

High-throughput

0.479

High

1192374

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

2

Small-scale

0.479

High

1192375

BICC1
Protein bicaudal C homolog 1

1

20

High-throughput

0.479

High

1192376

TDRD3
Tudor domain-containing protein 3

1

2

High-throughput

0.479

High

1192377

CNO10
CCR4-NOT transcription complex subunit 10

1

2

High-throughput

0.479

High

1192379

AGO3
Protein argonaute-3

1

9

High-throughput

0.479

High

1192381

MOV10
Helicase MOV-10

1

6

High-throughput

0.479

High

1192383

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

15

High-throughput

0.479

High

1192386

DCP1A
mRNA-decapping enzyme 1A

1

5

High-throughput

0.479

High

1192388

4ET
Eukaryotic translation initiation factor 4E transporter

1

2

High-throughput

0.479

High

1192393

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

6

High-throughput

0.479

High

1192394

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

6

High-throughput

0.479

High

1192395

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

10

High-throughput

0.479

High

1192396

CNOT2
CCR4-NOT transcription complex subunit 2

1

8

High-throughput

0.479

High

1192397

IBTK
Inhibitor of Bruton tyrosine kinase

1

1

High-throughput

0.479

High

1192398

HECW2
E3 ubiquitin-protein ligase HECW2

1

2

High-throughput

0.479

High

1192400

CNOT8
CCR4-NOT transcription complex subunit 8

1

6

High-throughput

0.479

High

1192402

CNOT7
CCR4-NOT transcription complex subunit 7

1

6

High-throughput

0.479

High

1192403

AGO2
Protein argonaute-2

1

9

High-throughput

0.479

High

1192404

CNO11
CCR4-NOT transcription complex subunit 11

1

2

High-throughput

0.479

High

1192405

AGO1
Protein argonaute-1

1

9

High-throughput

0.479

High

1192407

FZR1
Fizzy-related protein homolog

1

7

High-throughput

0.479

High

1192408

G3BP2
Ras GTPase-activating protein-binding protein 2

1

8

High-throughput

0.479

High

1192410

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

9

High-throughput

0.479

High

1192411

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

6

High-throughput

0.479

High

1192413

RTRAF
RNA transcription, translation and transport factor protein

1

1

High-throughput

0.479

High

1192414

FBW1A
F-box/WD repeat-containing protein 1A

1

6

High-throughput

0.479

High

1192416

R3HD2
R3H domain-containing protein 2

1

10

High-throughput

0.479

High

1192417

RTCB
RNA-splicing ligase RtcB homolog

1

1

High-throughput

0.479

High

1192418

MARF1
Meiosis regulator and mRNA stability factor 1

1

2

High-throughput

0.479

High

1192419

PRC2C
Protein PRRC2C

1

12

High-throughput

0.479

High

1192421

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

15

High-throughput

0.479

High

177925

TMPS2
Transmembrane protease serine 2

1

6

High-throughput

0.470

High

456893

FURIN
Furin

1

3

High-throughput

0.470

High

525976

IFM1
Interferon-induced transmembrane protein 1

1

6

High-throughput

0.470

High

726288

BASI
Basigin

1

2

High-throughput

0.470

High

965734

IFM3
Interferon-induced transmembrane protein 3

1

6

High-throughput

0.470

High

1192315

TM11B
Transmembrane protease serine 11B

1

6

High-throughput

0.470

High

1192341

CLC4D
C-type lectin domain family 4 member D

1

5

High-throughput

0.470

High

1192389

TMPS4
Transmembrane protease serine 4

1

6

High-throughput

0.470

High

1192406

CLC4E
C-type lectin domain family 4 member E

1

5

High-throughput

0.470

High

1192351

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.460

High

1192387

EXOS5
Exosome complex component RRP46

1

0

High-throughput

0.460

High

128880

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

0

High-throughput

0.458

High

409140

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

504319

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

654486

CALX
Calnexin

1

0

High-throughput

0.458

High

914174

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

1064446

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1074354

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1192352

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.458

High

1192382

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.458

High

1192385

NGB
Neuroglobin

1

0

High-throughput

0.458

High

1192390

ZCHC3
Zinc finger CCHC domain-containing protein 3

1

0

High-throughput

0.458

High

1192399

HDC
Headcase protein homolog

1

0

High-throughput

0.458

High

427005

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

11

High-throughput

0.457

High

665491

EPHA8
Ephrin type-A receptor 8

1

8

High-throughput

0.457

High

1046705

KLF5
Krueppel-like factor 5

1

8

High-throughput

0.457

High

1192366

KLF16
Krueppel-like factor 16

1

9

High-throughput

0.457

High

1192401

KLF15
Krueppel-like factor 15

1

9

High-throughput

0.457

High

1192412

DICER
Endoribonuclease Dicer

1

3

Small-scale

0.445

High

1192415

ST38L
Serine/threonine-protein kinase 38-like

1

1

High-throughput

0.445

High

1192356

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

1

High-throughput

0.439

High

379558

MYCN
N-myc proto-oncogene protein

1

12

High-throughput

0.437

High

385089

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.437

High

429911

CATL1
Procathepsin L

1

3

High-throughput

0.437

High

431245

CATB
Cathepsin B

1

4

High-throughput

0.437

High

600604

EPHA1
Ephrin type-A receptor 1

1

7

High-throughput

0.437

High

637269

CATS
Cathepsin S

1

3

High-throughput

0.437

High

795769

MAGA3
Melanoma-associated antigen 3

1

3

Small-scale

0.437

High

877784

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.437

High

1192330

RN214
RING finger protein 214

1

4

High-throughput

0.437

High

1192339

DCAF4
DDB1- and CUL4-associated factor 4

1

4

High-throughput

0.437

High

1192342

ZCH14
Zinc finger CCHC domain-containing protein 14

1

7

High-throughput

0.437

High

1192368

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.437

High

1192391

POTE1
Protection of telomeres protein 1

1

2

High-throughput

0.437

High

1085418

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.426

High

473138

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

763028

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.279

Low

1087954

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

0

High-throughput

0.279

Low

648810

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

940640

F193A
Protein FAM193A

1

0

High-throughput

0.249

Low

1159385

FBX42
F-box only protein 42

1

0

High-throughput

0.249

Low

1192336

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1192357

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

1192378

SFXN1
Sideroflexin-1

1

0

High-throughput

0.249

Low

1017158

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024