HitPredict

Interactor 1: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	24457600, 27634302, 36517590
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 746
+	Hs
		516536 PABP1_HUMAN (1-644): 0: 542: 74.54		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		582312 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		516645 PABP1_HUMAN (1-644): 0: 542: 74.54		NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82
+	Sc
		376833 PABP_YEAST (2-290): 4.28e-66: 228: 30.07		SET2_YEAST (470-733): 1.22e-59: 216: 25.56
+	Hs
		331720 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03
+	Hs
		582478 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		SETD2_HUMAN (190-732): 2.07e-89: 310: 16.64