HitPredict

Interactor 1: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:1990904 - ribonucleoprotein complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 582
+	Hs
		516541 PABP1_HUMAN (1-644): 0: 542: 74.54		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116542 PABP3_HUMAN (1-644): 7.04e-175: 513: 68.98		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116304 PAP1L_HUMAN (1-636): 6.79e-165: 487: 63.89		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		403212 PABP4_HUMAN (1-644): 0: 585: 100.00		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		516495 PABP4_HUMAN (1-644): 0: 585: 100.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		1031407 PABP4_HUMAN (1-644): 0: 585: 100.00		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		474021 PABP4_HUMAN (1-644): 0: 585: 100.00		PAB4L_HUMAN (1-203): 9.24e-35: 136: 11.85
+	Hs
		516689 PABP1_HUMAN (1-644): 0: 542: 74.54		PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11
+	Hs
		516339 PABP1_HUMAN (1-644): 0: 542: 74.54		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		516568 PABP1_HUMAN (1-644): 0: 542: 74.54		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		516616 PABP1_HUMAN (1-644): 0: 542: 74.54		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		516635 PABP1_HUMAN (1-644): 0: 542: 74.54		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		1031367 PABP4_HUMAN (1-644): 0: 585: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1031344 PABP4_HUMAN (1-644): 0: 585: 100.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Mm
		665745 PABP1_MOUSE (1-644): 0: 542: 74.69		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Hs
		516561 PABP1_HUMAN (1-644): 0: 542: 74.54		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1119141 PAP1L_HUMAN (1-636): 6.79e-165: 487: 63.89		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	At
		285476 PABP2_ARATH (2-451): 5.23e-66: 230: 24.09		LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20