HitPredict

Interactor 1: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Interactor 2: IF2B2 (Q9Y6M1)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: IGF2BP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0010494 - cytoplasmic stress granule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 644 Hs			1 599
+	Hs
		128165 PABP4_HUMAN (1-644): 0: 585: 100.00		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		1031481 PABP4_HUMAN (1-644): 0: 585: 100.00		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		516769 PABP1_HUMAN (1-644): 0: 542: 74.54		IF2B2_HUMAN (1-599): 1.06e-146: 438: 100.00
+	Hs
		128007 PABP1_HUMAN (1-644): 0: 542: 74.54		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		516722 PABP1_HUMAN (1-644): 0: 542: 74.54		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Xl
		251139 EPABA_XENLA (1-640): 5.49e-171: 503: 65.32		IF23A_XENLA (2-599): 4.02e-132: 400: 64.55
+	Hs
		516531 PABP1_HUMAN (1-644): 0: 542: 74.54		PCBP2_HUMAN (422-597): 7.25e-36: 140: 26.92
+	Hs
		1031431 PABP4_HUMAN (1-644): 0: 585: 100.00		FUBP3_HUMAN (196-414): 3.06e-18: 90.2: 15.51
+	Hs
		959392 PABP4_HUMAN (1-644): 0: 585: 100.00		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01
+	Hs
		516642 PABP1_HUMAN (1-644): 0: 542: 74.54		FUBP3_HUMAN (196-414): 3.06e-18: 90.2: 15.51
+	Hs
		516439 PABP1_HUMAN (1-644): 0: 542: 74.54		HNRPK_HUMAN (386-596): 5.84e-18: 88.9: 17.09
+	Mm
		665747 PABP1_MOUSE (1-644): 0: 542: 74.69		HNRPK_MOUSE (386-596): 5.84e-18: 88.9: 17.09
+	Hs
		516468 PABP1_HUMAN (1-644): 0: 542: 74.54		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01
+	Hs
		516530 PABP1_HUMAN (1-644): 0: 542: 74.54		PCBP1_HUMAN (422-530): 8.21e-11: 65.8: 25.69
+	Hs
		1055884 ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		128020 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		582530 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		128270 PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		582308 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		PCBP1_HUMAN (422-530): 8.21e-11: 65.8: 25.69
+	Zm
		8143 A0A1D6ELH4_MAIZE (1-89): 1.11e-15: 82.6: 30.34		A0A1D6ELH4_MAIZE (3-215): 2.04e-15: 81.6: 14.54